1. Programmatic implementation of population-based colorectal cancer screening and follow-up of abnormal screening results. We embrace clinical informatics, AI, and implementation science methods to design, develop, and deliver economic and effective services for patients and health systems.

2. Translational program in GI mucosal biology. The gastrointestinal compartment is a window to studies of viral reservoirs and their impact on persistence, immune activation, and chronic disease (e.g., HIV, COVID-19). Approaches employed: organoid models, isolation of epithelial cells and lymphocytes, single-cell, spatial transcriptomic analysis, microbial profiling, and blood-based profiling.