
Associate Professor
Dermatology
Custom People Group
Lab website: https://scharschmidtlab.ucsf.edu/
Publications
0652 The emerging fungal pathogen Candida auris induces IFN? to colonize mammalian hair follicles.
Journal of Investigative Dermatology
Paving the physician-scientist career path: from grassroots gathering to national forum.
JCI insight
Skin microbiome and dermatologic disorders.
The Journal of clinical investigation
The emerging fungal pathogen Candida auris induces IFNγ to colonize mammalian hair follicles.
bioRxiv : the preprint server for biology
Epidermal Penetration Increases with Age and May Contribute to Systemic Inflammation.
The Journal of investigative dermatology
Staphylococcus aureus-specific skin resident memory T cells protect against bacteria colonization but exacerbate atopic dermatitis-like flares in mice.
The Journal of allergy and clinical immunology
Preclinical Atopic Dermatitis Skin in Infants: An Emerging Research Area.
The Journal of investigative dermatology
218 Staphylococcus aureus-specific skin resident memory T cells protect against bacteria colonization but exacerbate atopic dermatitis-like flares in mice.
Journal of Investigative Dermatology
Commensal myeloid crosstalk in neonatal skin regulates long-term cutaneous type 17 inflammation.
bioRxiv : the preprint server for biology
LB1714 Increased epidermal penetration in aged skin modulates systemic inflammation.
Journal of Investigative Dermatology
FLG Deficiency in Mice Alters the Early-Life CD4+ T-Cell Response to Skin Commensal Bacteria.
The Journal of investigative dermatology
544 Commensal induced accumulation of monocyte-derived cells in neonatal skin regulates long-term cutaneous type 17 inflammation.
Journal of Investigative Dermatology
561 Filaggrin deficiency confers an altered early life T cell response to commensal skin bacteria.
Journal of Investigative Dermatology
Intestinal inflammation alters the antigen-specific immune response to a skin commensal.
Cell reports
Early life host-microbe interactions in skin.
Cell host & microbe
Skin immunity: dissecting the complex biology of our body's outer barrier.
Mucosal immunology
Baby's skin bacteria: first impressions are long-lasting.
Trends in immunology
Layilin Anchors Regulatory T Cells in Skin.
Journal of immunology (Baltimore, Md. : 1950)
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-ß activation.
Science immunology
Elucidating the Role of the Skin Barrier Protein Filaggrin in the Adaptive Immune Response to Commensals.
The FASEB Journal
Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet.
Cell host & microbe
002 Colitis alters the antigen-specific response to skin commensal bacteria and predisposes to neutrophilic skin inflammation.
Journal of Investigative Dermatology
Colitis alters the antigen-specific response to skin commensal bacteria and predisposes to neutrophilic skin inflammation.
The Journal of Immunology
Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.
Cell reports. Medicine
MAIT cells are imprinted by the microbiota in early life and promote tissue repair.
The Journal of Immunology
Atlas of atopic dermatitis.
The Journal of allergy and clinical immunology
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
MAIT cells are imprinted by the microbiota in early life and promote tissue repair.
Science (New York, N.Y.)
The TNFRSF members CD27 and OX40 coordinately limit TH17 differentiation in regulatory T cells.
Science immunology
The microbiome in patients with atopic dermatitis.
The Journal of allergy and clinical immunology
Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization.
Microbiome
Skin Commensal Antigens: Taking the Road Less Traveled.
Trends in immunology
Fighting staph: Not child’s play.
Science translational medicine
Successful treatment of mucous membrane pemphigoid with bortezomib.
JAAD case reports
S. aureus
induces IL-36 to start the itch.
Science translational medicine
Growing good bugs with mom’s milk.
Science translational medicine
ILC
regs
: The new kid in class.
Science translational medicine
Interferon with antitumor immunity.
Science translational medicine
Skin Dysbiosis Goes "Off-Leish".
Cell host & microbe
A vitamin to D-crease sunburn.
Science translational medicine
Measuring inflammation in IBD with an OSM-ostat.
Science translational medicine
Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.
Cell host & microbe
When TLRs fail, IgG has your back.
Science translational medicine
Establishing Tolerance to Commensal Skin Bacteria: Timing Is Everything.
Dermatologic clinics
014 Commensal microbes augment expression of the hair follicle chemokine Ccl20 to facilitate accumulation of Tregs in neonatal skin.
Journal of Investigative Dermatology
Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing.
Journal of immunology (Baltimore, Md. : 1950)
Paradoxical benefits of psychological stress in inflammatory dermatoses models are glucocorticoid mediated.
The Journal of investigative dermatology
What Lives On Our Skin: Ecology, Genomics and Therapeutic Opportunities Of the Skin Microbiome.
Drug discovery today. Disease mechanisms
Immune reconstitution reactions in human immunodeficiency virus-negative patients: report of a case and review of the literature.
JAMA dermatology
Neurogenic rosacea: a distinct clinical subtype requiring a modified approach to treatment.
Archives of dermatology
Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis.
The Journal of investigative dermatology
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
The Journal of allergy and clinical immunology
Matriptase-deficient mice exhibit ichthyotic skin with a selective shift in skin microbiota.
The Journal of investigative dermatology
Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
The Journal of investigative dermatology
Modeling atopic dermatitis with increasingly complex mouse models.
The Journal of investigative dermatology
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.
The Journal of biological chemistry
Clinical trial design issues raised during recombinant DNA advisory committee review of gene transfer protocols.
Human gene therapy
Clinical Trial Design Issues Raised During Recombinant DNA Advisory Committee Review of Gene Transfer Protocols.
Human gene therapy
Estrogen receptor beta-selective transcriptional activity and recruitment of coregulators by phytoestrogens.
The Journal of biological chemistry