Nature chemical biology

Transcriptional regulation of living materials via extracellular electron transfer.

Nature chemical biology

Graham AJ, Partipilo G, Dundas CM, Miniel Mahfoud IE, Halwachs KN, Holwerda AJ, Simmons TR, FitzSimons TM, Coleman SM, Rinehart R, Chiu D, Tyndall AE, Sajbel KC, Rosales AM, Keitz BK

Profiling the proximal proteome of the activated μ-opioid receptor.

Nature chemical biology

Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R

De novo-designed transmembrane proteins bind and regulate a cytokine receptor.

Nature chemical biology

Mravic M, He L, Kratochvil HT, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF

Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.

Nature chemical biology

Mukherjee IA, Gabel C, Noinaj N, Bondy-Denomy J, Chang L

Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.

Nature chemical biology

Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA

Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases.

Nature chemical biology

Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ, IGI Testing Consortium, Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA

Accelerated RNA detection using tandem CRISPR nucleases.

Nature chemical biology

Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ, IGI Testing Consortium , Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA

Deep mutational scanning reveals the structural basis for α-synuclein activity.

Nature chemical biology

Newberry RW, Leong JT, Chow ED, Kampmann M, DeGrado WF

Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.

Nature chemical biology

Ravalin M, Theofilas P, Basu K, Opoku-Nsiah KA, Assimon VA, Medina-Cleghorn D, Chen YF, Bohn MF, Arkin M, Grinberg LT, Craik CS, Gestwicki JE

FTO controls reversible m6Am RNA methylation during snRNA biogenesis.

Nature chemical biology

Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur JJ, Rentmeister A, Gross SS, Pellizzoni L, Debart F, Goodarzi H, Jaffrey SR

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