
Professor
Medicine
+1 415 476-5728
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Publications
Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data.
Frontiers in immunology
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system.
Open biology
A tumor-specific mechanism of Treg enrichment mediated by the integrin αvβ8.
Science immunology
Structural Studies avß8 Integrin by Single Particle Cryo-EM.
Microscopy and Microanalysis
Integrin avß8-expressing tumor cells evade host immunity by regulating TGF-ß activation in immune cells.
JCI insight
Cryo-EM structure of the avß8 integrin reveals a mechanism for stabilizing integrin extension.
Nature structural & molecular biology
An OX40/OX40L interaction directs successful immunity to hepatitis B virus.
Science translational medicine
Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice.
Cellular and molecular gastroenterology and hepatology
Role of IL-17A in murine models of COPD airway disease.
American journal of physiology. Lung cellular and molecular physiology
Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man.
Hepatology (Baltimore, Md.)
TGF-ß-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease.
Journal of immunology (Baltimore, Md. : 1950)
Transforming Growth Factor-ß and Interleukin-1ß Signaling Pathways Converge on the Chemokine CCL20 Promoter.
The Journal of biological chemistry
A critical role for dendritic cells in the evolution of IL-1ß-mediated murine airway disease.
Journal of immunology (Baltimore, Md. : 1950)
Selective targeting of TGF-ß activation to treat fibroinflammatory airway disease.
Science translational medicine
Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B.
The Journal of clinical investigation
Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity.
Nature medicine
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin avß8-mediated activation of TGF-ß.
The Journal of clinical investigation
IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B.
The Journal of clinical investigation
Blockade of NKG2D on NKT cells prevents hepatitis and the acute immune response to hepatitis B virus.
Proceedings of the National Academy of Sciences of the United States of America
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function.
The Journal of experimental medicine
Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo.
Proceedings of the National Academy of Sciences of the United States of America
The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1.
The Journal of cell biology
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo.
Proceedings of the National Academy of Sciences of the United States of America