Emmanuelle Waubant, MD, PhD

Professor
Neurology
+1 415 514-2468

Dr Waubant trained as a neurologist in Toulouse, France. She continued her training as a neuroimmunology fellow in Dr Stephen Hauser’s UCSF laboratory, focusing on matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP), and their role in migration of lymphocytes through equivalents of the blood-brain barrier. In 1994, Dr Waubant returned to Toulouse to complete her 2-year junior faculty/chief residency in neurology. Dr Waubant later returned as a clinical research fellow at the UCSF MS Center with Dr Donald Goodkin. During that 3-year period, she furthered her in vitro MMP work to the study in the human disease that helped to understand the role of MMP-9 and TIMP-1 in patients with MS and their relationship to disease activity. After completing her clinical research training at the UCSF MS center, Dr Waubant returned to France to lead a clinical research center at Salpetriere Hospital in Paris for 2 years. She returned to the UCSF MS center in September 2001 as a faculty. She is also the Race to Erase MS Medical Director and coordinates clinical research collaborations between 6 American MS Centers of Excellence. With the support of the National MS Society, she has started a regional pediatric MS clinic at UCSF in January 2006 that she directs and has since seen over 350 patients with pediatric MS or related disorders. She is the editor of the first text book on Pediatric MS and related disorders. Dr Waubant is At-large Board Director and on the program committee of the the American Committee on Treatment and Research in MS and the Chair of the U.S. Pediatric MS Steering Committee. She is also chairing the international Clinical Trial Task Force for pediatric MS.
Dr Waubant’s specific interests include the translation of promising agents from the bench to the bedside, understanding factors that predict the response to MS therapies, and risk factors for pediatric MS susceptibility and disease modification. Currently, she is the co-lead investigator for a trial of vitamin D in relapsing-remitting MS sponsored by the NMSS and is the recipient of a large multicenter NIH grant to study risk factors in pediatric MS and their interactions. Dr. Waubant is also a very active mentor for junior investigators.

Publications: 

Epidemiology and Impact of Social Hardships in Children With Multiple Sclerosis in the United States.

Neurology

Wilson E, Meeks HD, Barney BJ, Waltz M, Canenguez K, Casper TC, Rose JW, Rodriguez M, Tillema JM, Chitnis T, Gorman MP, Rensel M, Abrams AW, Krupp LB, Lotze TE, Fisher KS, Shukla NM, Schreiner TL, Mar SS, Waubant E, Virupakshaiah A, Wheeler YS, Ness JM, Benson LA, as the United States Network of Pediatric Multiple Sclerosis Centers

Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation.

bioRxiv : the preprint server for biology

Jank L, Singh SS, Lee J, Dhukhwa A, Siavoshi F, Joshi D, Minney V, Gupta K, Ghimire S, Deme P, Schoeps VA, Soman K, Ladakis D, Smith M, Borkowski K, Newman J, Baranzini SE, Waubant EL, Fitzgerald KC, Mangalam A, Haughey N, Kornberg M, Chamling X, Calabresi PA, Bhargava P

Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations: A Review.

JAMA neurology

Hua LH, Solomon AJ, Tenembaum S, Scalfari A, Rovira À, Rostasy K, Newsome SD, Marrie RA, Magyari M, Kantarci O, Hemmer B, Hemingway C, Harnegie MP, Graves JS, Cohen JA, Bove R, Banwell B, Corboy JR, Waubant E

Distinct plasma lipids predict axonal injury and multiple sclerosis activity.

Journal of neurology, neurosurgery, and psychiatry

Schoeps VA, Bhargava P, Virupakshaiah A, Ladakis DC, Moseley C, Chong J, Aaen G, Graves JS, Benson L, Gorman MP, Rensel M, Abrams A, Mar S, Lotze TE, Chitnis T, Waldman A, Krupp L, Rodriguez M, Tillema JM, Rose J, Schreiner T, Qureshi F, Peterson S, Barcellos LF, Casper TC, Newman J, Borkowski K, Waubant E, US Network of Pediatric MS Centers

Early Adversity and Socioeconomic Factors in Pediatric Multiple Sclerosis: A Case-Control Study.

Neurology(R) neuroimmunology & neuroinflammation

Jensen SKG, Camposano S, Berens A, Waltz M, Krupp LB, Charvet L, Belman AL, Aaen GS, Benson LA, Candee M, Casper TC, Chitnis T, Graves J, Wheeler YS, Kahn I, Lotze TE, Mar SS, Rensel M, Rodriguez M, Rose JW, Rubin JP, Tillema JM, Waldman AT, Weinstock-Guttman B, Barcellos LF, Waubant E, Gorman MP, US Network of Pediatric Multiple Sclerosis Centers

Mediterranean diet and associations with the gut microbiota and pediatric-onset multiple sclerosis using trivariate analysis.

Communications medicine

Mirza AI, Zhu F, Knox N, Black LJ, Daly A, Bonner C, Van Domselaar G, Bernstein CN, Marrie RA, Hart J, Yeh EA, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H

Central vein sign and trigeminal lesions of multiple sclerosis visualised by 7T MRI.

Journal of neurology, neurosurgery, and psychiatry

Jing J, Zhang Z, Su L, Gao C, Guo A, Liu X, Wang H, Zhang X, Liu Y, Comi G, Waubant E, Shi FD, Tian DC

Increased intraindividual variability (IIV) in reaction time is the earliest indicator of cognitive change in MS: A two-year observational study.

International journal of clinical and health psychology : IJCHP

Pilloni G, Casper TC, Mar S, Ness J, Schreiner T, Waltz M, Waubant E, Weinstock-Guttman B, Wheeler Y, Krupp L, Charvet L

MOG CNS Autoimmunity and MOGAD.

Neurology(R) neuroimmunology & neuroinflammation

Moseley CE, Virupakshaiah A, Forsthuber TG, Steinman L, Waubant E, Zamvil SS

Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease.

Journal of neurology, neurosurgery, and psychiatry

Virupakshaiah A, Schoeps VA, Race J, Waltz M, Sharayah S, Nasr Z, Moseley CE, Zamvil SS, Gaudioso C, Schuette A, Casper TC, Rose J, Flanagan EP, Rodriguez M, Tillema JM, Chitnis T, Gorman MP, Graves JS, Benson LA, Rensel M, Abrams A, Krupp L, Lotze TE, Aaen G, Wheeler Y, Schreiner T, Waldman A, Chong J, Mar S, Waubant E

Association of nutritional intake with clinical and imaging activity in pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Mohan SD, Peterson S, Brenton JN, Carmichael SL, Virupakshaiah A, Rodriguez M, Tillema JM, Mar S, Rensel MR, Abrams A, Chitnis T, Benson L, Gorman M, Lotze T, Shukla N, Graves J, Aaen G, Casper TC, Waubant E

Unveiling the Performance of Proposed MOGAD Diagnostic Criteria.

Neurology

Schoeps VA, Virupakshaiah A, Waubant E

Clinical and magnetic resonance imaging outcomes in pediatric-onset MS patients on fingolimod and ocrelizumab.

Multiple sclerosis and related disorders

Nasr Z, Casper TC, Waltz M, Virupakshaiah A, Lotze T, Shukla N, Chitnis T, Gorman M, Benson LA, Rodriguez M, Tillema JM, Krupp L, Schreiner T, Mar S, Rensel M, Rose J, Liu C, Guye S, Manlius C, Waubant E, U.S. Network of Pediatric Multiple Sclerosis Centers

Life-Threatening MOG Antibody-Associated Hemorrhagic ADEM With Elevated CSF IL-6.

Neurology(R) neuroimmunology & neuroinflammation

Virupakshaiah A, Moseley CE, Elicegui S, Gerwitz LM, Spencer CM, George E, Shah M, Cree BAC, Waubant E, Zamvil SS

Assessment of dietary intake and its inflammatory potential in persons with pediatric-onset multiple sclerosis.

Multiple sclerosis and related disorders

Bitarafan S, Zhu F, Mirza A, Bernstein CN, Van Domselaar G, Marrie RA, Yeh EA, Zhao Y, Banwell B, Waubant E, Tremlett H

Gene-environment interactions: Epstein-Barr virus infection and risk of pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Ziaei A, Solomon O, Casper TC, Waltz M, Weinstock-Guttman B, Aaen G, Wheeler Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Waldman AT, Krupp L, James JA, Hart J, Barcellos LF, Waubant E

Clinical and Imaging Findings in Children with Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease (MOGAD): From Presentation to Relapse.

AJNR. American journal of neuroradiology

George E, Russ JB, Validrighi A, Early H, Mamlouk MD, Glenn OA, Francisco CM, Waubant E, Lindan C, Li Y

Design recommendations for studies that evaluate multiple sclerosis fatigue interventions.

Frontiers in psychiatry

Ghajarzadeh M, Waubant E, Nourbakhsh B

A cross-sectional study of MRI features and the gut microbiome in pediatric-onset multiple sclerosis.

Annals of clinical and translational neurology

Zhu F, Zhao Y, Arnold DL, Bar-Or A, Bernstein CN, Bonner C, Graham M, Hart J, Knox N, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Banwell B, Waubant E, Tremlett H, US Network of Pediatric MS Centers, the Canadian Pediatric Demyelinating Disease Network

Gene-environment interactions and risk of pediatric-onset multiple sclerosis associated with time spent outdoors.

Multiple sclerosis and related disorders

Nasr Z, Virupakshaiah A, Schoeps VA, Cherbuin N, Casper TC, Waltz M, Hart J, Rodriguez M, Gorman MP, Benson LA, Chitnis T, Rensel M, Abrams A, Krupp L, Waldman AT, Lotze T, Aaen GS, Mar S, Schreiner T, Wheeler Y, Rose J, Shukla NM, Barcellos LF, Lucas R, Waubant E

Short-chain fatty acid producers in the gut are associated with pediatric multiple sclerosis onset.

Annals of clinical and translational neurology

Schoeps VA, Zhou X, Horton MK, Zhu F, McCauley KE, Nasr Z, Virupakshaiah A, Gorman MP, Benson LA, Weinstock-Guttman B, Waldman A, Banwell BL, Bar-Or A, Marrie RA, van Domselaar G, O'Mahony J, Mirza AI, Bernstein CN, Yeh EA, Casper TC, Lynch SV, Tremlett H, Baranzini S, Waubant E, US Network of Pediatric MS Centers

Susceptibility-based imaging aids accurate distinction of pediatric-onset MS from myelin oligodendrocyte glycoprotein antibody-associated disease.

Multiple sclerosis (Houndmills, Basingstoke, England)

Sacco S, Virupakshaiah A, Papinutto N, Schoeps VA, Akula A, Zhao H, Arona J, Stern WA, Chong J, Hart J, Zamvil SS, Sati P, Henry RG, Waubant E

Characteristics and predictors of disease course in children initially presenting with ADEM.

Multiple sclerosis and related disorders

Rutatangwa A, Aaen G, Krysko KM, Belman A, Benson LA, Chitnis T, Gorman M, Goyal M, Graves JS, Wheeler Y, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Rodriguez M, Rose J, Schreiner T, Tillema JM, Weinstock-Guttman B, Waltz M, Casper TC, Waubant E, U.S. Network of Pediatric MS Centers

Differential diagnosis of suspected multiple sclerosis: an updated consensus approach.

The Lancet. Neurology

Solomon AJ, Arrambide G, Brownlee WJ, Flanagan EP, Amato MP, Amezcua L, Banwell BL, Barkhof F, Corboy JR, Correale J, Fujihara K, Graves J, Harnegie MP, Hemmer B, Lechner-Scott J, Marrie RA, Newsome SD, Rocca MA, Royal W, Waubant EL, Yamout B, Cohen JA

Serum neurofilament light chain reference database for individual application in paediatric care: a retrospective modelling and validation study.

The Lancet. Neurology

Abdelhak A, Petermeier F, Benkert P, Schädelin S, Oechtering J, Maleska Maceski A, Kabesch M, Geis T, Laub O, Leipold G, Gobbi C, Zecca C, Green A, Tumani H, Willemse E, Wiendl H, Granziera C, Kappos L, Leppert D, Waubant E, Wellmann S, Kuhle J

Several serum lipid metabolites are associated with relapse risk in pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Virupakshaiah A, Ladakis DC, Nourbakhsh B, Bhargava P, Dilwali S, Schoeps V, Borkowski K, Newman JW, Waubant E

Demographic Features and Clinical Course of Patients With Pediatric-Onset Multiple Sclerosis on Newer Disease-Modifying Treatments.

Pediatric neurology

Malani Shukla N, Casper TC, Ness J, Wheeler Y, Chitnis T, Lotze T, Gorman M, Benson L, Weinstock-Guttmann B, Aaen G, Rodriguez M, Tillema JM, Krupp L, Schreiner T, Mar S, Goyal M, Rensel M, Abrams A, Rose J, Waltz M, Liu T, Manlius C, Waubant E, U.S. Network of Pediatric Multiple Sclerosis Centers

High-dose vitamin D3 supplementation in relapsing-remitting multiple sclerosis: a randomised clinical trial.

EClinicalMedicine

Cassard SD, Fitzgerald KC, Qian P, Emrich SA, Azevedo CJ, Goodman AD, Sugar EA, Pelletier D, Waubant E, Mowry EM

High serum neurofilament levels are observed close to disease activity events in pediatric-onset MS and MOG antibody-associated diseases.

Multiple sclerosis and related disorders

Ziaei A, Nasr Z, Hart J, Francisco C, Rutatangwa A, Leppert D, Kuhle J, Flanagan E, Waubant E

A Phase 1 Study of Oral Vitamin D3 in Boys and Young Men With X-Linked Adrenoleukodystrophy.

Neurology. Genetics

Van Haren KP, Cunanan K, Awani A, Gu M, Pe?a D, Chromik LC, Pova?an M, Rossi NC, Goodman J, Sundaram V, Winterbottom J, Raymond GV, Cowan T, Enns GM, Waubant E, Steinman L, Barker PB, Spielman D, Fatemi A

Characteristics of pediatric patients with multiple sclerosis and related disorders infected with SARS-CoV-2.

Multiple sclerosis (Houndmills, Basingstoke, England)

Schreiner T, Wilson-Murphy M, Mendelt-Tillema J, Waltz M, Codden R, Benson L, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Roalstad S, Rodriguez M, Rose J, Shukla N, Waubant E, Wheeler Y, Casper TC, Chitnis T

Silent findings: Examination of asymptomatic demyelination in a pediatric US cohort.

Multiple sclerosis and related disorders

Bhise V, Waltz M, Casper TC, Aaen G, Benson L, Chitnis T, Gorman M, Goyal MS, Wheeler Y, Lotze T, Mar S, Rensel M, Abrams A, Rodriguez M, Rose J, Schreiner T, Shukla N, Waubant E, Weinstock-Guttman B, Ness J, Krupp L, Mendelt-Tillema J, U.S. Network of Pediatric Multiple Sclerosis Centers

Rare and low-frequency coding genetic variants contribute to pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Horton MK, Shim JE, Wallace A, Graves JS, Aaen G, Greenberg B, Mar S, Wheeler Y, Weinstock-Guttman B, Waldman A, Schreiner T, Rodriguez M, Tillema JM, Chitnis T, Krupp L, Casper TC, Rensel M, Hart J, Quach HL, Quach DL, Schaefer C, Waubant E, Barcellos LF

Gene-environment interactions increase the risk of paediatric-onset multiple sclerosis associated with household chemical exposures.

Journal of neurology, neurosurgery, and psychiatry

Nasr Z, Schoeps VA, Ziaei A, Virupakshaiah A, Adams C, Casper TC, Waltz M, Rose J, Rodriguez M, Tillema JM, Chitnis T, Graves JS, Benson L, Rensel M, Krupp L, Waldman AT, Weinstock-Guttman B, Lotze T, Greenberg B, Aaen G, Mar S, Schreiner T, Hart J, Simpson-Yap S, Mesaros C, Barcellos LF, Waubant E

A Cross-Trait, Mendelian Randomization Study to Investigate Whether Migraine Is a Risk Factor for Multiple Sclerosis.

Neurology

Horton MK, Robinson SC, Shao X, Quach H, Quach D, Choudhary V, Bellesis KH, Dorin P, Mei J, Chinn T, Meyers TJ, Bakshi N, Marcus JF, Waubant E, Schaefer CA, Barcellos LF

Stroke Outcomes and Hyperacute Treatment Utilization in Multiple Sclerosis.

Multiple sclerosis and related disorders

Schoeps VA, Waubant E, Singh N

Therapeutic Response in Pediatric Neuromyelitis Optica Spectrum Disorder.

Neurology

Umeton RP, Waltz M, Aaen GS, Benson L, Gorman M, Goyal M, Graves JS, Harris Y, Krupp L, Lotze TE, Shukla NM, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, Roalstad S, Rodriguez M, Rose J, Waubant E, Weinstock-Guttman B, Casper C, Chitnis T, and the U.S. Network of Pediatric MS Centers

Using an animal model to predict the effective human dose for oral multiple sclerosis drugs.

Clinical and translational science

Liu W, Yu Z, Wang Z, Waubant EL, Zhai S, Benet LZ

MRI lesions can often precede trigeminal neuralgia symptoms by years in multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Dilwali S, Mark I, Waubant E

MOG and AQP4 Antibodies among Children with Multiple Sclerosis and Controls.

Annals of neurology

Gaudioso CM, Mar S, Casper TC, Codden R, Nguyen A, Aaen G, Benson L, Chitnis T, Francisco C, Gorman MP, Goyal MS, Graves J, Greenberg BM, Hart J, Krupp L, Lotze T, Narula S, Pittock SJ, Rensel M, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Wheeler Y, Waubant E, Flanagan EP, United States Network of Pediatric Multiple Sclerosis Centers

A new look at cognitive functioning in pediatric MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Krupp LB, Waubant E, Waltz M, Casper TC, Belman A, Wheeler Y, Ness J, Graves J, Gorman M, Benson L, Mar S, Goyal M, Schreiner T, Weinstock-Guttman B, Rodriguez M, Tillema JM, Lotze T, Aaen G, Rensel M, Rose J, Chitinis T, George A, Charvet LE, and the US Network of Pediatric MS Centers

The metabolic potential of the paediatric-onset multiple sclerosis gut microbiome.

Multiple sclerosis and related disorders

Mirza AI, Zhu F, Knox N, Forbes JD, Bonner C, Van Domselaar G, Bernstein CN, Graham M, Marrie RA, Hart J, Yeh EA, Arnold DL, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H

Reply to "Spinal cord atrophy is a preclinical marker of progressive MS".

Annals of neurology

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of CaliforniaSan Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG

Stability of the gut microbiota in persons with paediatric-onset multiple sclerosis and related demyelinating diseases.

Multiple sclerosis (Houndmills, Basingstoke, England)

Liang G, Zhu F, Mirza AI, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E, Tremlett H, Canadian Paediatric Demyelinating Disease Network

Preventing Multiple Sclerosis: The Pediatric Perspective.

Frontiers in neurology

Hardy D, Chitnis T, Waubant E, Banwell B

Effect of fingolimod on health-related quality of life in paediatric patients with multiple sclerosis: results from the phase 3 PARADIGMS Study.

BMJ neurology open

Krupp L, Banwell B, Chitnis T, Deiva K, Gaertner J, Ghezzi A, Huppke P, Waubant E, DeLasHeras V, Azmon A, Karan R

Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution.

Multiple sclerosis (Houndmills, Basingstoke, England)

Ziaei A, Lavery AM, Shao XM, Adams C, Casper TC, Rose J, Candee M, Weinstock-Guttman B, Aaen G, Harris Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Hart J, Waldman AT, Barcellos LF, Waubant E

Spinal cord atrophy predicts progressive disease in relapsing multiple sclerosis.

Annals of neurology

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of California, San Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG

Metagenomic Analysis of the Pediatric-Onset Multiple Sclerosis Gut Microbiome.

Neurology

Mirza AI, Zhu F, Knox N, Forbes JD, Van Domselaar G, Bernstein CN, Graham M, Marrie RA, Hart J, Yeh EA, Arnold D, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H

The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes.

Annals of clinical and translational neurology

Tremlett H, Zhu F, Arnold D, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E, US Network of Pediatric MS Centers, the Canadian Pediatric Demyelinating Disease Network

Association Between Time Spent Outdoors and Risk of Multiple Sclerosis.

Neurology

Sebastian P, Cherbuin N, Barcellos LF, Roalstad S, Casper C, Hart J, Aaen GS, Krupp L, Benson L, Gorman M, Candee M, Chitnis T, Goyal M, Greenberg B, Mar S, Rodriguez M, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Graves J, Waubant E, Lucas R, US Network of Pediatric Multiple Sclerosis Centers

Etiological research in pediatric multiple sclerosis: A tool to assess environmental exposures (PEDiatric Italian Genetic and enviRonment ExposurE Questionnaire).

Multiple sclerosis journal - experimental, translational and clinical

Pilotto S, Gencarelli J, Bova S, Gerosa L, Baroncini D, Olivotto S, Alfei E, Zaffaroni M, Suppiej A, Cocco E, Trojano M, Amato MP, D'Alfonso S, Martinelli-Boneschi F, Waubant E, Ghezzi A, Bergamaschi R, Pugliatti M

Interocular Difference in Retinal Nerve Fiber Layer Thickness Predicts Optic Neuritis in Pediatric-Onset Multiple Sclerosis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Waldman AT, Benson L, Sollee JR, Lavery AM, Liu GW, Green AJ, Waubant E, Heidary G, Conger D, Graves J, Greenberg B

Paediatric multiple sclerosis: a lesson from TERIKIDS.

The Lancet. Neurology

Sormani MP, Waubant E

Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism.

Cell reports. Medicine

Fitzgerald KC, Smith MD, Kim S, Sotirchos ES, Kornberg MD, Douglas M, Nourbakhsh B, Graves J, Rattan R, Poisson L, Cerghet M, Mowry EM, Waubant E, Giri S, Calabresi PA, Bhargava P

Family Perspectives on Clinical Research for Pediatric Multiple Sclerosis: Enhancing Equity.

Journal of patient experience

Mandel LA, O'Donnell E, Canenguez K, Castro-Mendoza PB, Lotze T, Waubant E, Weinstock-Guttmann B, Chitnis T

High titers of myelin oligodendrocyte glycoprotein antibody are only observed close to clinical events in pediatrics.

Multiple sclerosis and related disorders

Lui A, Chong J, Flanagan E, Abrams AW, Krysko KM, Arikan B, Francisco C, Rutatangwa A, Waubant E, Ziaei A

Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome.

Neurology(R) neuroimmunology & neuroinflammation

Santoro JD, Kerr LM, Codden R, Casper TC, Greenberg BM, Waubant E, Kong SW, Mandl KD, Gorman MP

Myelin-oligodendrocyte glycoprotein antibody-associated disease.

The Lancet. Neurology

Marignier R, Hacohen Y, Cobo-Calvo A, Pröbstel AK, Aktas O, Alexopoulos H, Amato MP, Asgari N, Banwell B, Bennett J, Brilot F, Capobianco M, Chitnis T, Ciccarelli O, Deiva K, De Sèze J, Fujihara K, Jacob A, Kim HJ, Kleiter I, Lassmann H, Leite MI, Linington C, Meinl E, Palace J, Paul F, Petzold A, Pittock S, Reindl M, Sato DK, Selmaj K, Siva A, Stankoff B, Tintore M, Traboulsee A, Waters P, Waubant E, Weinshenker B, Derfuss T, Vukusic S, Hemmer B

Gut microbiome is associated with multiple sclerosis activity in children.

Annals of clinical and translational neurology

Horton MK, McCauley K, Fadrosh D, Fujimura K, Graves J, Ness J, Wheeler Y, Gorman MP, Benson LA, Weinstock-Guttman B, Waldman A, Rodriguez M, Tillema JM, Krupp L, Belman A, Mar S, Rensel M, Chitnis T, Casper TC, Rose J, Hart J, Shao X, Tremlett H, Lynch SV, Barcellos LF, Waubant E, U.S. Network of Pediatric MS Centers

Familial History of Autoimmune Disorders Among Patients With Pediatric Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Greenberg BM, Casper TC, Mar SS, Ness JM, Plumb P, Liang S, Goyal M, Weinstock-Guttman B, Rodriguez M, Aaen GS, Belman A, Barcellos LF, Rose JW, Gorman MP, Benson LA, Candee M, Chitnis T, Harris YC, Kahn IL, Roalstad S, Hart J, Lotze TE, Rensel M, Rubin JP, Schreiner TL, Tillema JM, Waldman AT, Krupp L, Graves J, Drake K, Waubant E

Ethical considerations in the treatment of multiple sclerosis fatigue.

Multiple sclerosis and related disorders

Nourbakhsh B, Waubant E, Evers AWM, Solomon AJ

A pilot study of oxidative pathways in MS fatigue: randomized trial of N-acetyl cysteine.

Annals of clinical and translational neurology

Krysko KM, Bischof A, Nourbakhsh B, Henry RG, Revirajan N, Manguinao M, Nguyen K, Akula A, Li Y, Waubant E

Safety evaluation of shorter infusion for ocrelizumab in a substudy of the Phase IIIb CHORDS trial.

Annals of clinical and translational neurology

Bermel RA, Waubant E, Pardo G, Bass A, Repovic P, Newsome S, Lindsey JW, Kile D, Pradhan A, Musch B, Zabeti A

Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial.

The Lancet. Neurology

Nourbakhsh B, Revirajan N, Morris B, Cordano C, Creasman J, Manguinao M, Krysko K, Rutatangwa A, Auvray C, Aljarallah S, Jin C, Mowry E, McCulloch C, Waubant E

Biosensor vital sign detects multiple sclerosis progression.

Annals of clinical and translational neurology

Krysko KM, Akhbardeh A, Arjona J, Nourbakhsh B, Waubant E, Antoine Gourraud P, Graves JS

Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS.

AJNR. American journal of neuroradiology

Sacco S, Caverzasi E, Papinutto N, Cordano C, Bischof A, Gundel T, Cheng S, Asteggiano C, Kirkish G, Mallot J, Stern WA, Bastianello S, Bove RM, Gelfand JM, Goodin DS, Green AJ, Waubant E, Wilson MR, Zamvil SS, Cree BA, Hauser SL, Henry RG

Improved relapse recovery in paediatric compared to adult multiple sclerosis.

Brain : a journal of neurology

Chitnis T, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Roalstad S, Rose J, Weiner HL, Casper TC, Rodriguez M

Pediatric Multiple Sclerosis Severity Score in a Large U.S. Cohort.

Neurology

Santoro JD, Waltz M, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rensel M, Rodriguez M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Hurtubise BF, Roalstad S, Rose J, Casper TC, Chitnis T

A validation study for remote testing of cognitive function in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Barcellos LF, Horton M, Shao X, Bellesis KH, Chinn T, Waubant E, Bakshi N, Marcus J, Benedict RH, Schaefer C

Ocrelizumab exposure in the second trimester of pregnancy without neonatal B-cell depletion.

Multiple sclerosis and related disorders

Rolfes M, Rutatangwa A, Waubant E, Krysko KM

Two-armed active comparator trials are unethical in paediatric multiple sclerosis - Commentary.

Multiple sclerosis (Houndmills, Basingstoke, England)

Waubant E

Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy in paediatric patients with multiple sclerosis: Results from the PARADIGMS study.

Multiple sclerosis (Houndmills, Basingstoke, England)

Chitnis T, Banwell B, Krupp L, Arnold DL, Bar-Or A, Brück W, Giovannoni G, Greenberg B, Ghezzi A, Waubant E, Rostasy K, Deiva K, Huppke P, Wolinsky JS, Zhang Y, Azmon A, K-Laflamme A, Karan R, Gärtner J

Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation.

The Journal of clinical investigation

Bhargava P, Smith MD, Mische L, Harrington EP, Fitzgerald KC, Martin KA, Kim S, Reyes AAA, Gonzalez-Cardona J, Volsko C, Tripathi A, Singh S, Varanasi K, Lord HN, Meyers KR, Taylor M, Gharagozloo M, Sotirchos ES, Nourbakhsh B, Dutta R, Mowry E, Waubant E, Calabresi PA

Dare we mention the C-word?

Multiple sclerosis and related disorders

Giovannoni G, Hawkes CH, Lechner-Scott J, Levy M, Waubant E

Rituximab in patients with pediatric multiple sclerosis and other demyelinating disorders of the CNS: Practical considerations.

Multiple sclerosis (Houndmills, Basingstoke, England)

Ghezzi A, Banwell B, Bar-Or A, Chitnis T, Dale RC, Gorman M, Kornek B, Krupp L, Krysko KM, Nosadini M, Rostasy K, Salzer J, Schreiner T, Tenembaum S, Waubant E

Do you believe in Gad?

Multiple sclerosis and related disorders

Maghzi AH, Sicotte NL, Waubant E

Changes in patient and physician attitudes resulting from COVID-19 in neuromyelitis optica spectrum disorder and multiple sclerosis.

Multiple sclerosis and related disorders

Salama S, Giovannoni G, Hawkes CH, Lechner-Scott J, Waubant E, Levy M

Autoimmune Encephalitis in Children: A Case Series at a Tertiary Care Center.

Journal of child neurology

Rutatangwa A, Mittal N, Francisco C, Nash K, Waubant E

Real-world effectiveness of initial disease-modifying therapies in pediatric MS.

Annals of neurology

Krysko KM, Graves JS, Rensel M, Weinstock-Guttman B, Rutatangwa A, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Goyal MS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waltz M, Casper TC, Waubant E

Is multiple sclerosis a risk factor for infections?

Multiple sclerosis and related disorders

Lechner-Scott J, Waubant E, Levy M, Hawkes C, Giovannoni G

The future of microbiome research in neuroinflammatory disorders.

Multiple sclerosis and related disorders

Waubant E, Pröbstel AK, Levy M, Hawkes CH, Giovannoni G, Lechner-Scott J, Tremlett H

Big pharma and social responsibility.

Multiple sclerosis and related disorders

Hawkes CH, Giovannoni G, Levy M, Lechner-Scott J, Waubant E

The COVID-19 pandemic and the use of MS disease-modifying therapies.

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Lechner-Scott J, Levy M, Waubant E, Gold J

Effect of fingolimod on MRI outcomes in patients with paediatric-onset multiple sclerosis: results from the phase 3 PARADIGMS study.

Journal of neurology, neurosurgery, and psychiatry

Arnold DL, Banwell B, Bar-Or A, Ghezzi A, Greenberg BM, Waubant E, Giovannoni G, Wolinsky JS, Gärtner J, Rostásy K, Krupp L, Tardieu M, Brück W, Stites TE, Pearce GL, Häring DA, Merschhemke M, Chitnis T

Ageing and multiple sclerosis.

Multiple sclerosis and related disorders

Giovannoni G, Hawkes CH, Lechner-Scott J, Levy M, Waubant E

"Is this new medicine going to help me walk again?"

Multiple sclerosis and related disorders

Levy M, Waubant E, Hawkes C, Giovannoni G, Lechner-Scott J

Cognitive processing speed in pediatric-onset multiple sclerosis: Baseline characteristics of impairment and prediction of decline.

Multiple sclerosis (Houndmills, Basingstoke, England)

Wallach AI, Waltz M, Casper TC, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze TE, Mar S, Moodley M, Ness JM, Rensel M, Rodriguez M, Rose JW, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Charvet LE, Krupp LB

Silent symptoms of multiple sclerosis.

Multiple sclerosis and related disorders

Lechner-Scott J, Waubant E, Levy M, Hawkes C

Grassroot efforts towards diversity in MS care and research: Win-win for patients and science.

Multiple sclerosis and related disorders

Waubant E, Levy M, Lechner-Scott J, Giovannoni G, Hawkes C

The multiple sclerosis gut microbiota: A systematic review.

Multiple sclerosis and related disorders

Mirza A, Forbes JD, Zhu F, Bernstein CN, Van Domselaar G, Graham M, Waubant E, Tremlett H

Clinical Features and Outcomes of Pediatric Monophasic and Recurrent Idiopathic Optic Neuritis.

Journal of child neurology

Jonzzon S, Suleiman L, Yousef A, Young B, Hart J, Peschl P, Reindl M, Schaller KL, Bennett JL, Waubant E, Graves JS

Seafood, fatty acid biosynthesis genes, and multiple sclerosis susceptibility.

Multiple sclerosis (Houndmills, Basingstoke, England)

Langer-Gould A, Black LJ, Waubant E, Smith JB, Wu J, Gonzales EG, Shao X, Koebnick C, Lucas RM, Xiang A, Barcellos LF

Consistent control of disease activity with fingolimod versus IFN ß-1a in paediatric-onset multiple sclerosis: further insights from PARADIGMS.

Journal of neurology, neurosurgery, and psychiatry

Deiva K, Huppke P, Banwell B, Chitnis T, Gärtner J, Krupp L, Waubant E, Stites T, Pearce GL, Merschhemke M

Environmental and genetic risk factors for MS: an integrated review.

Annals of clinical and translational neurology

Waubant E, Lucas R, Mowry E, Graves J, Olsson T, Alfredsson L, Langer-Gould A

Implementing the 2017 McDonald criteria for the diagnosis of multiple sclerosis.

Nature reviews. Neurology

Zipp F, Oh J, Fragoso YD, Waubant E

Multiple sclerosis and migration revisited.

Multiple sclerosis and related disorders

Hawkes CH, Giovannoni G, Lechner-Scott J, Levy M, Waubant E

A retrospective cohort study of plasma exchange in central nervous system demyelinating events in children.

Multiple sclerosis and related disorders

Manguinao M, Krysko KM, Maddike S, Rutatangwa A, Francisco C, Hart J, Chong J, Graves JS, Waubant E

Editorial on: Eculizumab in aquaporin-4-positive neuromyelitis optica spectrum disorder.

Multiple sclerosis and related disorders

Pardo S, Giovannoni G, Hawkes C, Lechner-Scott J, Waubant E, Levy M

Introducing the International Women in Multiple Sclerosis network.

The Lancet. Neurology

Jokubaitis VG, Pröbstel AK, Arrambide G, Costello F, Waubant E

miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS.

Annals of clinical and translational neurology

Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee MS, Gorman M, Benson L, Mar S, Kahn I, Rose J, Casper TC, Quach H, Quach D, Schaefer C, Waubant E, Barcellos LF

Vitamin D genes influence MS relapses in children.

Multiple sclerosis (Houndmills, Basingstoke, England)

Graves JS, Barcellos LF, Krupp L, Belman A, Shao X, Quach H, Hart J, Chitnis T, Weinstock-Guttman B, Aaen G, Benson L, Gorman M, Greenberg B, Lotze T, Soe M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Casper TC, Waubant E

Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG.

Neurology

Waubant E, Banwell B, Wassmer E, Sormani MP, Amato MP, Hintzen R, Krupp L, Rostásy K, Tenembaum S, Chitnis T

Three suggestions to decrease the financial burden of MS treatments.

Multiple sclerosis and related disorders

Waubant E, Giovannoni G, Hawkes C, Lechner-Scott J, Levy M

One size doesn't fit all.

Multiple sclerosis and related disorders

Lechner-Scott J, Giovannoni G, Hawkes C, Levy M, Waubant E

Acute flaccid myelitis in the 21st century: reminiscence of poliomyelitis or a new emergent disease.

Multiple sclerosis and related disorders

Levy M, Giovannoni G, Hawkes C, Lechner-Scott J, Waubant E

Multiple Sclerosis and Vitamin D - Caviar or a Dog's Dinner?

Multiple sclerosis and related disorders

Hawkes C, Giovannoni G, Lechner-Scott J, Levy M, Waubant E

Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry.

PLoS genetics

Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, Krupp L, Gorman M, Benson L, Chitnis T, Mar S, Belman A, Casper TC, Rose J, Moodley M, Rensel M, Rodriguez M, Greenberg B, Kahn L, Rubin J, Schaefer C, Waubant E, Langer-Gould A, Barcellos LF

Should our treatment target in MS include the intrathecal plasma cell response?

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Levy M, Lechner-Scott J, Waubant E

Acquisition of Early Developmental Milestones and Need for Special Education Services in Pediatric Multiple Sclerosis.

Journal of child neurology

Aaen G, Waltz M, Vargas W, Makhani N, Ness J, Harris Y, Casper TC, Benson L, Candee M, Chitnis T, Gorman M, Graves J, Greenberg B, Lotze T, Mar S, Tillema JM, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Belman A, Waubant E, Krupp L

Pediatric glial fibrillary acidic protein meningoencephalomyelitis: A case report and review of the literature.

Multiple sclerosis and related disorders

Francisco C, Meddles K, Waubant E

Subclinical Saccadic Eye Movement Dysfunction in Pediatric Multiple Sclerosis.

Journal of child neurology

Yousef A, Devereux M, Gourraud PA, Jonzzon S, Suleiman L, Waubant E, Green A, Graves JS

Body mass index, but not vitamin D status, is associated with brain volume change in MS.

Neurology

Mowry EM, Azevedo CJ, McCulloch CE, Okuda DT, Lincoln RR, Waubant E, Hauser SL, Pelletier D

Vaccines and disease-modifying treatments.

Multiple sclerosis and related disorders

Waubant E, Giovannoni G, Hawkes C, Levy M

Puberty onset and pediatric multiple sclerosis activity in boys.

Multiple sclerosis and related disorders

Young B, Waubant E, Lulu S, Graves J

Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US.

Neurology

Krysko KM, Graves J, Rensel M, Weinstock-Guttman B, Aaen G, Benson L, Chitnis T, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Rodriguez M, Rose J, Waltz M, Charles Casper T, Waubant E

Several household chemical exposures are associated with pediatric-onset multiple sclerosis.

Annals of clinical and translational neurology

Mar S, Liang S, Waltz M, Casper TC, Goyal M, Greenberg B, Weinstock-Guttman B, Rodriguez M, Aaen G, Belman A, Barcellos LF, Rose J, Gorman M, Benson L, Candee M, Chitnis T, Harris Y, Kahn I, Roalsted S, Hart J, Lotze T, Moodley M, Ness J, Rensel M, Rubin J, Schreiner T, Tillema JM, Waldman A, Krupp L, Graves JS, Waubant E

Detection of HHV-6 and EBV and Cytokine Levels in Saliva From Children With Seizures: Results of a Multi-Center Cross-Sectional Study.

Frontiers in neurology

Bartolini L, Piras E, Sullivan K, Gillen S, Bumbut A, Lin CM, Leibovitch EC, Graves JS, Waubant EL, Chamberlain JM, Gaillard WD, Jacobson S

Refining the Nosology of Antigen-Specific Diseases Within the Spectrum of Neuromyelitis Optica.

Multiple sclerosis and related disorders

Levy M, Giovannoni G, Hawkes C, Waubant E

Altered tryptophan metabolism is associated with pediatric multiple sclerosis risk and course.

Annals of clinical and translational neurology

Nourbakhsh B, Bhargava P, Tremlett H, Hart J, Graves J, Waubant E

Urban air quality and associations with pediatric multiple sclerosis.

Annals of clinical and translational neurology

Lavery AM, Waubant E, Casper TC, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Charvet L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waldman AT

Heterogeneity in association of remote herpesvirus infections and pediatric MS.

Annals of clinical and translational neurology

Nourbakhsh B, Rutatangwa A, Waltz M, Rensel M, Moodley M, Graves J, Casper TC, Waldman A, Belman A, Greenberg B, Goyal M, Harris Y, Kahn I, Lotze T, Mar S, Schreiner T, Aaen G, Hart J, Ness J, Rubin J, Tillema JM, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Candee M, Weinstock-Guttman B, Shao X, Barcellos L, James J, Waubant E

Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis.

The New England journal of medicine

Chitnis T, Arnold DL, Banwell B, Brück W, Ghezzi A, Giovannoni G, Greenberg B, Krupp L, Rostásy K, Tardieu M, Waubant E, Wolinsky JS, Bar-Or A, Stites T, Chen Y, Putzki N, Merschhemke M, Gärtner J

Editors' Welcome.

Multiple sclerosis and related disorders

Hawkes CH, Giovannoni G, Levy M, Waubant E

Is cognitive impairment in multiple sclerosis reversible?

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Levy M, Waubant E

Diagnosing and caring for MS in Haiti.

Multiple sclerosis and related disorders

Waubant E, Berkowitz A, Giovannoni G, Hawkes C, Levy M

Correction to: Impact of an electronic monitoring device and behavioural feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE

Editors' Welcome: Pregnancy and progressive multifocal leukoencephalopathy.

Multiple sclerosis and related disorders

Levy M, Giovannoni G, Hawkes C, Waubant E

Early infectious exposures are not associated with increased risk of pediatric-onset multiple sclerosis.

Multiple sclerosis and related disorders

Suleiman L, Waubant E, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Gorman M, Goyal M, Greenberg B, Harris Y, Hart J, Kahn I, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Nourbakhsh B, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Casper TC, Waltz M, Graves JS

Prevalence of salivary human herpesviruses in pediatric multiple sclerosis cases and controls.

Multiple sclerosis (Houndmills, Basingstoke, England)

Leibovitch EC, Lin CM, Billioux BJ, Graves J, Waubant E, Jacobson S

Multiple sclerosis onset after granulocyte macrophage colony-stimulating factor withdrawal.

Multiple sclerosis and related disorders

Chong J, Cohen M, Waubant E

Are the high-costs of MS disease-modifying therapies justified?

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Levy M, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Hawkes C, Giovannoni G, Levy M, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Levy M, Lublin F, Waubant E

Effect of puberty on multiple sclerosis risk and course.

Multiple sclerosis (Houndmills, Basingstoke, England)

Waubant E

Gut microbiome and pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Tremlett H, Waubant E

The Gut Microbiota and Pediatric Multiple Sclerosis: Recent Findings.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Tremlett H, Waubant E

Ovarian aging is associated with gray matter volume and disability in women with MS.

Neurology

Graves JS, Henry RG, Cree BAC, Lambert-Messerlian G, Greenblatt RM, Waubant E, Cedars MI, Zhu A, Bacchetti P, Hauser SL, Oksenberg JR

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.

The Lancet. Neurology

Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, Correale J, Fazekas F, Filippi M, Freedman MS, Fujihara K, Galetta SL, Hartung HP, Kappos L, Lublin FD, Marrie RA, Miller AE, Miller DH, Montalban X, Mowry EM, Sorensen PS, Tintoré M, Traboulsee AL, Trojano M, Uitdehaag BMJ, Vukusic S, Waubant E, Weinshenker BG, Reingold SC, Cohen JA

Editors' Welcome.

Multiple sclerosis and related disorders

Waubant E, Giovannoni G, Hawkes C, Lublin F

The multiple sclerosis risk allele within the AHI1 gene is associated with relapses in children and adults.

Multiple sclerosis and related disorders

Graves JS, Barcellos LF, Simpson S, Belman A, Lin R, Taylor BV, Ponsonby AL, Dwyer T, Krupp L, Waubant E, van der Mei IAF

Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Azary S, Schreiner T, Graves J, Waldman A, Belman A, Guttman BW, Aaen G, Tillema JM, Mar S, Hart J, Ness J, Harris Y, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos LF, Lotze T, Carmichael SL, Roalstad S, Casper CT, Waubant E

Genetic risk factors for pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Lublin F, Giovannoni G, Hawkes C, Waubant E

Performance of 2010 McDonald criteria and 2016 MAGNIMS guidelines in the diagnosis of primary progressive multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Gajofatto A, Nourbakhsh B, Benedetti MD, Waubant E

Examining the contributions of environmental quality to pediatric multiple sclerosis.

Multiple sclerosis and related disorders

Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Hawkes C, Giovannoni G, Lublin F, Waubant E

Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Zhou Y, Graves JS, Simpson S, Charlesworth JC, Mei IV, Waubant E, Barcellos LF, Belman A, Krupp L, Lucas R, Ponsonby AL, Taylor BV

Psychiatric disorders in children with demyelinating diseases of the central nervous system.

Multiple sclerosis (Houndmills, Basingstoke, England)

Pakpoor J, Goldacre R, Schmierer K, Giovannoni G, Waubant E, Goldacre MJ

The 'Field Hypothesis': rebound activity after stopping disease-modifying therapies.

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Waubant E, Lublin F

Dietary factors and pediatric multiple sclerosis: A case-control study.

Multiple sclerosis (Houndmills, Basingstoke, England)

Pakpoor J, Seminatore B, Graves JS, Schreiner T, Waldman AT, Lotze TE, Belman A, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, McDonald JC, Hart J, Ness JM, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Kahn I, Rose J, Carmichael SL, Roalstad S, Waltz M, Casper TC, Waubant E

Clinical Reasoning: A 16-year-old girl with subacute weakness and sensory loss.

Neurology

Quintanilla-Bordás C, Nourbakhsh B, Strober J, Raffel C, Waubant E

Editors' welcome.

Multiple sclerosis and related disorders

Waubant E, Giovannoni G, Hawkes C, Lublin F

Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE

Editors' Welcome.

Multiple sclerosis and related disorders

Lublin F, Giovannoni G, Hawkes C, Waubant E

Maternal and Perinatal Exposures Are Associated With Risk for Pediatric-Onset Multiple Sclerosis.

Pediatrics

Graves JS, Chitnis T, Weinstock-Guttman B, Rubin J, Zelikovitch AS, Nourbakhsh B, Simmons T, Waltz M, Casper TC, Waubant E

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS.

Neurology

Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E

The gut microbiome in human neurological disease: A review.

Annals of neurology

Tremlett H, Bauer KC, Appel-Cresswell S, Finlay BB, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Hawkes C, Giovannoni G, Lublin F, Waubant E

Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Schwartz CE, Grover SA, Powell VE, Noguera A, Mah JK, Mar S, Mednick L, Banwell BL, Alper G, Rensel M, Gorman M, Waldman A, Schreiner T, Waubant E, Yeh EA

Serum neurofilament is associated with progression of brain atrophy and disability in early MS.

Neurology

Kuhle J, Nourbakhsh B, Grant D, Morant S, Barro C, Yaldizli Ö, Pelletier D, Giovannoni G, Waubant E, Gnanapavan S

The multiple sclerosis microbiome?

Annals of translational medicine

Tremlett H, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Giovannoni G, Hawkes C, Lublin F, Waubant E

Distinct effects of obesity and puberty on risk and age at onset of pediatric MS.

Annals of clinical and translational neurology

Chitnis T, Graves J, Weinstock-Guttman B, Belman A, Olsen C, Misra M, Aaen G, Benson L, Candee M, Gorman M, Greenberg B, Krupp L, Lotze T, Mar S, Ness J, Rose J, Rubin J, Schreiner T, Tillema J, Waldman A, Rodriguez M, Casper C, Waubant E

Editors' Welcome.

Multiple sclerosis and related disorders

Hawkes C, Lublin F, Giovannoni G, Waubant E

Rebound Syndrome in Multiple Sclerosis After Fingolimod Cessation-Reply.

JAMA neurology

Hatcher SE, Waubant E, Graves JS

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls.

BMC neurology

Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Spencer CM, Lynch SV, Zamvil SS, Waubant E

Environmental and genetic factors in pediatric inflammatory demyelinating diseases.

Neurology

Waubant E, Ponsonby AL, Pugliatti M, Hanwell H, Mowry EM, Hintzen RQ

International Pediatric MS Study Group Global Members Symposium report.

Neurology

Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ

Biopsy-Supported Tumefactive Demyelination of the Central Nervous System in Children.

Journal of child neurology

Hanumanthe SB, Francisco C, Hart J, Graves J, Waubant E

Clinical trials for pediatric MS should be prioritized to test only one or two of the most promising agents - NO.

Multiple sclerosis (Houndmills, Basingstoke, England)

Francisco C, Graves J, Waubant E

Sex differences and subclinical retinal injury in pediatric-onset MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Graves JS, Chohan H, Cedars B, Arnow S, Yiu H, Waubant E, Green A

Characteristics of Children and Adolescents With Multiple Sclerosis.

Pediatrics

Belman AL, Krupp LB, Olsen CS, Rose JW, Aaen G, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze T, Ness J, Rodriguez M, Tillema JM, Waubant E, Weinstock-Guttman B, Casper TC

Rebound Syndrome in Patients With Multiple Sclerosis After Cessation of Fingolimod Treatment.

JAMA neurology

Hatcher SE, Waubant E, Nourbakhsh B, Crabtree-Hartman E, Graves JS

Dietary salt intake and time to relapse in paediatric multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Nourbakhsh B, Graves J, Casper TC, Lulu S, Waldman A, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Ness J, Rubin J, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos L, Waubant E

Gut microbiota in early pediatric multiple sclerosis: a case-control study.

European journal of neurology

Tremlett H, Fadrosh DW, Faruqi AA, Zhu F, Hart J, Roalstad S, Graves J, Lynch S, Waubant E

Subcortical grey matter volumes predict subsequent walking function in early multiple sclerosis.

Journal of the neurological sciences

Nourbakhsh B, Azevedo C, Maghzi AH, Spain R, Pelletier D, Waubant E

Gut microbiota composition and relapse risk in pediatric MS: A pilot study.

Journal of the neurological sciences

Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Lynch S, Waubant E

The challenge of comorbidity in clinical trials for multiple sclerosis.

Neurology

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA

A case-control study of dietary salt intake in pediatric-onset multiple sclerosis.

Multiple sclerosis and related disorders

McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, Candee M, Krupp LB, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Barcellos LF, Laraia B, Rose J, Roalstad S, Simmons T, Casper TC, Waubant E

Recommendations for observational studies of comorbidity in multiple sclerosis.

Neurology

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA

Genetic predictors of relapse rate in pediatric MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Graves JS, Barcellos LF, Shao X, Noble J, Mowry EM, Quach H, Belman A, Casper TC, Krupp LB, Waubant E

Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report.

Neurology

Chitnis T, Ness J, Krupp L, Waubant E, Hunt T, Olsen CS, Rodriguez M, Lotze T, Gorman M, Benson L, Belman A, Weinstock-Guttman B, Aaen G, Graves J, Patterson M, Rose JW, Casper TC

Acute Flaccid Myelitis of Unknown Etiology in California, 2012-2015.

JAMA

Van Haren K, Ayscue P, Waubant E, Clayton A, Sheriff H, Yagi S, Glenn-Finer R, Padilla T, Strober JB, Aldrovandi G, Wadford DA, Chiu CY, Xia D, Harriman K, Watt JP, Glaser CA

Longitudinal associations between MRI and cognitive changes in very early MS.

Multiple sclerosis and related disorders

Nourbakhsh B, Nunan-Saah J, Maghzi AH, Julian LJ, Spain R, Jin C, Lazar A, Pelletier D, Waubant E

Longitudinal associations between brain structural changes and fatigue in early MS.

Multiple sclerosis and related disorders

Nourbakhsh B, Azevedo C, Nunan-Saah J, Maghzi AH, Spain R, Pelletier D, Waubant E

Relapses in multiple sclerosis: Relationship to disability.

Multiple sclerosis and related disorders

Goodin DS, Reder AT, Bermel RA, Cutter GR, Fox RJ, John GR, Lublin FD, Lucchinetti CF, Miller AE, Pelletier D, Racke MK, Trapp BD, Vartanian T, Waubant E

Multiple sclerosis patients have a diminished serologic response to vitamin D supplementation compared to healthy controls.

Multiple sclerosis (Houndmills, Basingstoke, England)

Bhargava P, Steele SU, Waubant E, Revirajan NR, Marcus J, Dembele M, Cassard SD, Hollis BW, Crainiceanu C, Mowry EM

Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis.

JAMA neurology

Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG

Update on biomarkers in neuromyelitis optica.

Neurology(R) neuroimmunology & neuroinflammation

Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S

Neuropsychological correlates of multiple sclerosis across the lifespan.

Multiple sclerosis (Houndmills, Basingstoke, England)

Nunan-Saah J, Paulraj SR, Waubant E, Krupp LB, Gomez RG

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.

JAMA neurology

Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT, Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K

Gut microbiota in multiple sclerosis: possible influence of immunomodulators.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research

Cantarel BL, Waubant E, Chehoud C, Kuczynski J, DeSantis TZ, Warrington J, Venkatesan A, Fraser CM, Mowry EM

Menarche increases relapse risk in pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Lulu S, Graves J, Waubant E

Retinal axonal loss in very early stages of multiple sclerosis.

European journal of neurology

Maghzi AH, Graves J, Revirajan N, Spain R, Liu S, McCulloch CE, Pelletier D, Green AJ, Waubant E

Patient preferences for attributes of multiple sclerosis disease-modifying therapies: development and results of a ratings-based conjoint analysis.

International journal of MS care

Wilson LS, Loucks A, Gipson G, Zhong L, Bui C, Miller E, Owen M, Pelletier D, Goodin D, Waubant E, McCulloch CE

Prolonged Remission in Neuromyelitis Optica Following Cessation of Rituximab Treatment.

Journal of child neurology

Weinfurtner K, Graves J, Ness J, Krupp L, Milazzo M, Waubant E

Treatment adherence and transitioning youth in pediatric multiple sclerosis.

Multiple sclerosis and related disorders

Lulu S, Julian L, Shapiro E, Hudson K, Waubant E

Protective environmental factors for neuromyelitis optica.

Neurology

Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E

Precision medicine in chronic disease management: The multiple sclerosis BioScreen.

Annals of neurology

Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL

The vitamin D to ameliorate multiple sclerosis (VIDAMS) trial: study design for a multicenter, randomized, double-blind controlled trial of vitamin D in multiple sclerosis.

Contemporary clinical trials

Bhargava P, Cassard S, Steele SU, Azevedo C, Pelletier D, Sugar EA, Waubant E, Mowry EM

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014.

MMWR. Morbidity and mortality weekly report

Ayscue P, Van Haren K, Sheriff H, Waubant E, Waldron P, Yagi S, Yen C, Clayton A, Padilla T, Pan C, Reichel J, Harriman K, Watt J, Sejvar J, Nix WA, Feikin D, Glaser C

The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps.

Journal of child neurology

Casper TC, Rose JW, Roalstad S, Waubant E, Aaen G, Belman A, Chitnis T, Gorman M, Krupp L, Lotze TE, Ness J, Patterson M, Rodriguez M, Weinstock-Guttman B, Browning B, Graves J, Tillema JM, Benson L, Harris Y

Spinal cord gray matter atrophy correlates with multiple sclerosis disability.

Annals of neurology

Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG

Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis.

Multiple sclerosis and related disorders

Maghzi AH, Revirajan N, Julian LJ, Spain R, Mowry EM, Liu S, Jin C, Green AJ, McCulloch CE, Pelletier D, Waubant E

Patient centered decision making: use of conjoint analysis to determine risk-benefit trade-offs for preference sensitive treatment choices.

Journal of the neurological sciences

Wilson L, Loucks A, Bui C, Gipson G, Zhong L, Schwartzburg A, Crabtree E, Goodin D, Waubant E, McCulloch C

Defining the clinical course of multiple sclerosis: the 2013 revisions.

Neurology

Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH

A randomized controlled phase II trial of riluzole in early multiple sclerosis.

Annals of clinical and translational neurology

Waubant E, Maghzi AH, Revirajan N, Spain R, Julian L, Mowry EM, Marcus J, Liu S, Jin C, Green A, McCulloch CE, Pelletier D

Atypical cases of scleroderma en coup de sabre.

Journal of child neurology

Kraus V, Lawson EF, von Scheven E, Tihan T, Garza J, Nathan RG, Cordoro KM, Waubant E

Longitudinally extensive optic neuritis in pediatric patients.

Journal of child neurology

Graves J, Kraus V, Soares BP, Hess CP, Waubant E

Rituximab use in pediatric central demyelinating disease.

Pediatric neurology

Beres SJ, Graves J, Waubant E

MS and related disorders: groundbreaking news.

The Lancet. Neurology

Waubant E, Cross A

Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study.

BMC neurology

Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R

Effects of rituximab on lymphocytes in multiple sclerosis and neuromyelitis optica.

Multiple sclerosis and related disorders

Graves J, Vinayagasundaram U, Mowry EM, Matthews IR, Marino JA, Cheng J, Waubant E

Association of multiple sclerosis susceptibility variants and early attack location in the CNS.

PloS one

Mowry EM, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E

Multiple sclerosis susceptibility genes: associations with relapse severity and recovery.

PloS one

Mowry EM, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E

Neuroprotection in multiple sclerosis: a therapeutic approach.

CNS drugs

Maghzi AH, Minagar A, Waubant E

Rituximab in relapsing and progressive forms of multiple sclerosis: a systematic review.

PloS one

Castillo-Trivino T, Braithwaite D, Bacchetti P, Waubant E

Therapeutic advances in pediatric multiple sclerosis.

The Journal of pediatrics

Van Haren K, Waubant E

International Pediatric MS Study Group Clinical Trials Summit: meeting report.

Neurology

Chitnis T, Tardieu M, Amato MP, Banwell B, Bar-Or A, Ghezzi A, Kornberg A, Krupp LB, Pohl D, Rostasy K, Tenembaum S, Waubant E, Wassmer E

Humoral-targeted immunotherapies in multiple sclerosis.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Lulu S, Waubant E

Copy number variation in pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

McElroy JP, Krupp LB, Johnson BA, McCauley JL, Qi Z, Caillier SJ, Gourraud PA, Yu J, Nathanson L, Belman AL, Hauser SL, Waubant E, Hedges DJ, Oksenberg JR

Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, James JA

Cognitive impairment occurs in children and adolescents with multiple sclerosis: results from a United States network.

Journal of child neurology

Julian L, Serafin D, Charvet L, Ackerson J, Benedict R, Braaten E, Brown T, O'Donnell E, Parrish J, Preston T, Zaccariello M, Belman A, Chitnis T, Gorman M, Ness J, Patterson M, Rodriguez M, Waubant E, Weinstock-Guttman B, Yeh A, Krupp LB

EDSS variability before randomization may limit treatment discovery in primary progressive MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Zhang J, Waubant E, Cutter G, Wolinsky JS, Glanzman R

Treatment of Neuromyelitis Optica: Review and Recommendations.

Multiple sclerosis and related disorders

Kimbrough DJ, Fujihara K, Jacob A, Lana-Peixoto MA, Leite MI, Levy M, Marignier R, Nakashima I, Palace J, de Seze J, Stuve O, Tenembaum SN, Traboulsee A, Waubant E, Weinshenker BG, Wingerchuk DM

Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis.

Annals of neurology

Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D

Antibodies to potassium channels in multiple sclerosis.

The New England journal of medicine

Cross AH, Waubant E

Overview of treatment options in multiple sclerosis.

The Journal of clinical psychiatry

Waubant E

Early recognition and diagnosis of multiple sclerosis.

The Journal of clinical psychiatry

Waubant E

Randomized controlled trial of atorvastatin in clinically isolated syndrome: the STAyCIS study.

Neurology

Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Iklé D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS

Unilateral thalamic deep brain stimulation for disabling kinetic tremor in multiple sclerosis.

Neurosurgery

Hosseini H, Mandat T, Waubant E, Agid Y, Lubetzki C, Lyon-Caen O, Stankoff B, Jedynak P, Cesaro P, Palfi S, Nguyen JP

Relapse severity and recovery in early pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Fay AJ, Mowry EM, Strober J, Waubant E

Incidence of acquired CNS demyelinating syndromes in a multiethnic cohort of children.

Neurology

Langer-Gould A, Zhang JL, Chung J, Yeung Y, Waubant E, Yao J

Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies.

Multiple sclerosis international

Teunissen CE, Tumani H, Bennett JL, Berven FS, Brundin L, Comabella M, Franciotta D, Federiksen JL, Fleming JO, Furlan R, Hintzen RQ, Hughes SG, Jimenez CR, Johnson MH, Killestein J, Krasulova E, Kuhle J, Magnone MC, Petzold A, Rajda C, Rejdak K, Schmidt HK, van Pesch V, Waubant E, Wolf C, Deisenhammer F, Giovannoni G, Hemmer B

Common viruses associated with lower pediatric multiple sclerosis risk.

Neurology

Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Chabas D, Strober J, McDonald J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, Oksenberg JR, James JA

Pediatric multiple sclerosis.

Neurologic clinics

Chitnis T, Krupp L, Yeh A, Rubin J, Kuntz N, Strober JB, Chabas D, Weinstock-Guttmann B, Ness J, Rodriguez M, Waubant E

Switching multiple sclerosis patients with breakthrough disease to second-line therapy.

PloS one

Castillo-Trivino T, Mowry EM, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E

Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria.

Annals of neurology

Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS

Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome.

Neurology

Okuda DT, Mowry EM, Cree BA, Crabtree EC, Goodin DS, Waubant E, Pelletier D

Vitamin D status and antibody levels to common viruses in pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Mowry EM, James JA, Krupp LB, Waubant E

Multiple sclerosis therapies in pediatric patients with refractory multiple sclerosis.

Archives of neurology

Yeh EA, Waubant E, Krupp LB, Ness J, Chitnis T, Kuntz N, Ramanathan M, Belman A, Chabas D, Gorman MP, Rodriguez M, Rinker JR, Weinstock-Guttman B

Pediatric multiple sclerosis.

Continuum (Minneapolis, Minn.)

Mowry EM, Waubant E

Health-related quality of life is reduced in pediatric multiple sclerosis.

Pediatric neurology

Mowry EM, Julian LJ, Im-Wang S, Chabas D, Galvin AJ, Strober JB, Waubant E

MS and the B cell controversy.

Biochimica et biophysica acta

Cross AH, Waubant E

Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis.

Annals of neurology

Mowry EM, Krupp LB, Milazzo M, Chabas D, Strober JB, Belman AL, McDonald JC, Oksenberg JR, Bacchetti P, Waubant E

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

Annals of neurology

Bar-Or A, Fawaz L, Fan B, Darlington PJ, Rieger A, Ghorayeb C, Calabresi PA, Waubant E, Hauser SL, Zhang J, Smith CH

Treatment of multiple sclerosis in children and adolescents.

Expert opinion on pharmacotherapy

Kuntz NL, Chabas D, Weinstock-Guttman B, Chitnis T, Yeh EA, Krupp L, Ness J, Rodriguez M, Waubant E

Younger children with MS have a distinct CSF inflammatory profile at disease onset.

Neurology

Chabas D, Ness J, Belman A, Yeh EA, Kuntz N, Gorman MP, Strober JB, De Kouchkovsky I, McCulloch C, Chitnis T, Rodriguez M, Weinstock-Guttman B, Krupp LB, Waubant E

Does race matter for multiple sclerosis?

Neurology

Cree B, Waubant E

Pediatric multiple sclerosis.

Nature reviews. Neurology

Yeh EA, Chitnis T, Krupp L, Ness J, Chabas D, Kuntz N, Waubant E

Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.

Annals of neurology

Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH

Difference in disease burden and activity in pediatric patients on brain magnetic resonance imaging at time of multiple sclerosis onset vs adults.

Archives of neurology

Waubant E, Chabas D, Okuda DT, Glenn O, Mowry E, Henry RG, Strober JB, Soares B, Wintermark M, Pelletier D

Absence of neuromyelitis optica IgG antibody in an active relapsing-remitting multiple sclerosis population.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Smith CH, Waubant E, Langer-Gould A

Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures.

Neurology

Mowry EM, Beheshtian A, Waubant E, Goodin DS, Cree BA, Qualley P, Lincoln R, George MF, Gomez R, Hauser SL, Okuda DT, Pelletier D

Pediatric multiple sclerosis.

Current treatment options in neurology

Waubant E, Chabas D

Clinical predictors of early second event in patients with clinically isolated syndrome.

Journal of neurology

Mowry EM, Pesic M, Grimes B, Deen SR, Bacchetti P, Waubant E

Demyelinating events in early multiple sclerosis have inherent severity and recovery.

Neurology

Mowry EM, Pesic M, Grimes B, Deen S, Bacchetti P, Waubant E

Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome.

Neurology

Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL, Pelletier D

The onset location of multiple sclerosis predicts the location of subsequent relapses.

Journal of neurology, neurosurgery, and psychiatry

Mowry EM, Deen S, Malikova I, Pelletier J, Bacchetti P, Waubant E

Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures.

Brain : a journal of neurology

Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini SE, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

Human molecular genetics

Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR

Switching first-line disease-modifying therapy after failure: impact on the course of relapsing-remitting multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Gajofatto A, Bacchetti P, Grimes B, High A, Waubant E

Vanishing MS T2-bright lesions before puberty: a distinct MRI phenotype?

Neurology

Chabas D, Castillo-Trivino T, Mowry EM, Strober JB, Glenn OA, Waubant E

Pediatric multiple sclerosis.

Current neurology and neuroscience reports

Chabas D, Strober J, Waubant E

Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial.

Annals of neurology

Bar-Or A, Calabresi PA, Arnold D, Arnlod D, Markowitz C, Shafer S, Kasper LH, Waubant E, Gazda S, Fox RJ, Panzara M, Sarkar N, Agarwal S, Smith CH

Spotlight on anti-CD20.

International MS journal

Waubant E

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis.

The New England journal of medicine

Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH

Predictors of the location of multiple sclerosis relapse.

Journal of neurology, neurosurgery, and psychiatry

Deen S, Bacchetti P, High A, Waubant E

Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study.

The Lancet. Neurology

Banwell B, Krupp L, Kennedy J, Tellier R, Tenembaum S, Ness J, Belman A, Boiko A, Bykova O, Waubant E, Mah JK, Stoian C, Kremenchutzky M, Bardini MR, Ruggieri M, Rensel M, Hahn J, Weinstock-Guttman B, Yeh EA, Farrell K, Freedman M, Iivanainen M, Sevon M, Bhan V, Dilenge ME, Stephens D, Bar-Or A

Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling.

Journal of neuroimmunology

Kantor AB, Deng J, Waubant E, Lin H, Becker CH, Lacy JR, Perrone AM, Bennett D, Goelz SE

Emerging therapies for MS.

Revue neurologique

Waubant E

Pediatric multiple sclerosis.

NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics

Chabas D, Green AJ, Waubant E

Acute pathological laughter.

Movement disorders : official journal of the Movement Disorder Society

Okuda DT, Chyung AS, Chin CT, Waubant E

Interferon beta babies.

Neurology

Waubant E, Sadovnick AD

An open label study of the effects of rituximab in neuromyelitis optica.

Neurology

Cree BA, Lamb S, Morgan K, Chen A, Waubant E, Genain C

Multiple sclerosis tremor and the Stewart-Holmes manoeuvre.

Movement disorders : official journal of the Movement Disorder Society

Waubant E, Tezenas du Montcel S, Jedynak C, Obadia M, Hosseini H, Damier P, Lubetzki C, Agid Y, Degos JD

Clinical characteristics of responders to interferon therapy for relapsing MS.

Neurology

Waubant E, Vukusic S, Gignoux L, Dubief FD, Achiti I, Blanc S, Renoux C, Confavreux C

Emerging disease modifying therapies for multiple sclerosis.

Expert opinion on emerging drugs

Waubant E

IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS.

Neurology

Waubant E, Goodkin D, Bostrom A, Bacchetti P, Hietpas J, Lindberg R, Leppert D

Interferon beta-1a in children with multiple sclerosis is well tolerated.

Neuropediatrics

Waubant E, Hietpas J, Stewart T, Dyme Z, Herbert J, Lacy J, Miller C, Rensel M, Schwid S, Goodkin D

IFN-beta1a may increase serum levels of TIMP-1 in patients with relapsing-remitting multiple sclerosis.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

Waubant E, Gee L, Miller K, Stabler G, Goodkin D

Relationship between serum levels of IL-10, MRI activity and interferon beta-1a therapy in patients with relapsing remitting MS.

Journal of neuroimmunology

Waubant E, Gee L, Bacchetti P, Sloan R, Cotleur A, Rudick R, Goodkin D

1H MRSI comparison of white matter and lesions in primary progressive and relapsing-remitting MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Suhy J, Rooney WD, Goodkin DE, Capizzano AA, Soher BJ, Maudsley AA, Waubant E, Andersson PB, Weiner MW

Magnetization transfer ratio in new MS lesions before and during therapy with IFNbeta-1a.

Neurology

Kita M, Goodkin DE, Bacchetti P, Waubant E, Nelson SJ, Majumdar S

A phase I trial of solubilized DR2:MBP84-102 (AG284) in multiple sclerosis.

Neurology

Goodkin DE, Shulman M, Winkelhake J, Waubant E, Andersson P, Stewart T, Nelson S, Fischbein N, Coyle PK, Frohman E, Jacobs L, Holcenberg J, Lee M, Mocci S

Serum MMP-9 and TIMP-1 levels are related to MRI activity in relapsing multiple sclerosis.

Neurology

Waubant E, Goodkin DE, Gee L, Bacchetti P, Sloan R, Stewart T, Andersson PB, Stabler G, Miller K

A pilot study of MRI activity before and during interferon beta-1a therapy.

Neurology

Waubant E, Goodkin DE, Sloan R, Andersson PB

A serial study of new MS lesions and the white matter from which they arise.

Neurology

Goodkin DE, Rooney WD, Sloan R, Bacchetti P, Gee L, Vermathen M, Waubant E, Abundo M, Majumdar S, Nelson S, Weiner MW

Cervical cord glioma in an HIV-positive patient.

European neurology

Waubant E, Delisle MB, Bonafé A, Gray F, Clanet M

How should we proceed with disease-modifying treatments for multiple sclerosis?

Lancet (London, England)

Andersson PB, Waubant E, Goodkin DE

T cell gelatinases mediate basement membrane transmigration in vitro.

Journal of immunology (Baltimore, Md. : 1950)

Leppert D, Waubant E, Galardy R, Bunnett NW, Hauser SL

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