Jennifer Lai, MD, MBA

Associate Professor
Medicine
+1 415 476-6422

Dr. Lai is a practicing general/transplant hepatologist and board-certified Physician Nutrition Specialist who specializes in caring for patients across the entire spectrum of liver disease, from diagnosis to liver transplant.

Dr. Lai is also a clinical investigator with a robust research program dedicated to improving the lives of patients living with chronic liver disease and to help more of them survive to transplant and thrive after. Her research program has been continuously supported by numerous organizations including the National Institutes of Health, American Association for the Study of Liver Diseases (AASLD), American Gastroenterological Association (AGA), American College of Gastroenterology (ACG), American Society of Transplantation (AST), and American Federation for Aging Research (AFAR), in addition to the generous support of grateful patients. She serves as director of the UCSF Health Advancing Research in Clinical Hepatology (ARCH), the research arm of the UCSF Division of GI/Hepatology, as well as director of Patient-Facing Research Core of the NIH-funded UCSF Liver Center.

Dr. Lai earned her B.S. from Stanford University and combined MD/MBA degrees from Tufts University School of Medicine, then completed her clinical training in Internal Medicine at Columbia University, and gastroenterology and advanced/transplant hepatology fellowships at UCSF. Dr. Lai has received many honors for her work including the SF Business Times Top 40 under 40 Leader award, AGA Young Investigator Award in Clinical Science, AST Clinical Science Career Development Award, Young Investigator Award from the International Liver Transplantation Society, and the UCSF Department of Medicine Resident Research Award. Currently, Dr. Lai serves as an Associate Editor for the Hepatology Journal (the premier hepatology journal) and a standing member of the U.S. FDA Gastrointestinal Drug Advisory Committee.

If you are interested in contributing to Dr. Lai's research program, please consider making a tax-deductible contribution: https://makeagift.ucsf.edu/LaiResearchFund

Publications: 

Development of a liver disease-Specific large language model chat Interface using retrieval augmented generation.

Hepatology (Baltimore, Md.)

Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K

Applying human-centered design to the construction of a cirrhosis management clinical decision support system.

Hepatology communications

Ge J, Buenaventura A, Berrean B, Purvis J, Fontil V, Lai JC, Pletcher MJ

Outcomes of high-grade immune checkpoint inhibitor hepatitis in hospitalized and non-hospitalized patients.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Li M, Wong D, Sack JS, Vogel AS, Hodi FS, Fong L, Lai JC, Zucker SD, Grover S

A modified hospital frailty risk score for patients with cirrhosis undergoing abdominal operations.

Hepatology (Baltimore, Md.)

Calthorpe L, Chiou SH, Rubin J, Huang CY, Feng S, Lai J

Financial burden following adult liver transplantation is common and associated with adverse recipient outcomes.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ufere NN, Serper M, Kaplan A, Horick N, Indriolo T, Li L, Satapathy N, Donlan J, Castano Jimenez JC, Lago-Hernandez C, Lieber S, Gonzalez C, Keegan E, Schoener K, Bethea E, Dageforde LA, Yeh H, El-Jawahri A, Park ER, Vodkin I, Schonfeld E, Nipp R, Desai A, Lai JC

Prevalence and Appropriateness of Polypharmacy in Older Adults with Inflammatory Bowel Diseases.

Digestive diseases and sciences

Kochar B, Rusher A, Araka E, Glasser R, Lai J, Ritchie C, Ananthakrishnan AN

Association of biological aging with frailty and post-transplant outcomes among adults with cirrhosis.

GeroScience

LaHue SC, Fuentealba M, Roa Diaz S, Seetharaman S, Garcia T, Furman D, Lai JC, Newman JC

A pragmatic tool to screen for pre-transplant cognitive impairment among potential candidates for liver transplant.

Clinical transplantation

Teles MS, Ruck JM, Jefferis A, Helmy S, Oh ES, Murriel EC, Lai JC, King EA

Caregivers' and providers' perspectives of social and medical care after pediatric liver transplant: Results from the multi-center SOCIAL-Tx study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Wadhwani SI, Alvarado A, Shifman HP, Bautista B, Yalung J, Squires JE, Campbell K, Ebel NH, Hsu E, Vittorio J, Zielsdorf S, Desai DM, Bucuvalas JC, Gottlieb L, Kotagal U, Lyles CR, Ackerman SL, Lai JC

Prevalence of cognitive impairment in liver transplant recipients.

Clinical transplantation

Berry K, Ruck JM, Barry F, Shui AM, Cortella A, Kent D, Seetharaman S, Wong R, VandeVrede L, Lai JC

Barriers and Facilitators to Exercise in Older Adults Awaiting Kidney Transplantation and Their Care Partners.

Kidney medicine

Sheshadri A, Elia JR, Garcia G, Abrams G, Adey DB, Lai JC, Sudore RL

The liver frailty index is a predictor of healthcare utilization after liver transplantation in older adults.

Clinical transplantation

Wang M, Shui AM, Ruck J, King E, Rahimi R, Kappus M, Volk ML, Ganger DR, Ladner DP, Duarte-Rojo A, Huang CY, Verna EC, Lai JC

Association of body mass index with post-liver transplant outcomes.

Clinical transplantation

Ruck JM, Shui AM, Jefferis AA, Duarte Rojo A, Rahimi RS, Ganger DR, Verna EC, Kappus M, Ladner DP, Segev DL, Volk M, Tevar A, King EA, Lai JC

Development of a Liver Disease-Specific Large Language Model Chat Interface using Retrieval Augmented Generation.

medRxiv : the preprint server for health sciences

Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K

Neighborhood Income is Associated with Healthcare Utilization in Pediatric Short Bowel Syndrome.

The Journal of pediatrics

Gutierrez SA, Pathak S, Raghu V, Shui A, Huang CY, Rhee S, McKenzie-Sampson S, Lai JC, Wadhwani SI

A chair-stand time of greater than 15 seconds is associated with an increased risk of death and hospitalization in cirrhosis.

Canadian liver journal

Nguyen VV, Wang S, Whitlock R, Xu C, Taneja S, Singh S, Abraldes JG, Burak K, Bailey RJ, Grab JD, Lai JC, Tandon P

Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Yalung JE, Shifman HP, Rasnick Manning E, Beck A, Bucuvalas J, Lai JC, Wadhwani SI

Caregiver Perceptions of Social Risk Screening in Pediatric Liver Transplantation: From the Multicenter SOCIAL-Tx Study.

Transplantation

Wadhwani SI, Kruse G, Squires J, Ebel N, Gupta N, Campbell K, Hsu E, Zielsdorf S, Vittorio J, Desai DM, Bucuvalas JC, Gottlieb LM, Lai JC

Association of State Medicaid Expansion Policies with Pediatric Liver Transplant Outcomes.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Shifman HP, Huang CY, Beck AF, Bucuvalas J, Perito ER, Hsu EK, Ebel NH, Lai JC, Wadhwani SI

Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity.

JGH open : an open access journal of gastroenterology and hepatology

Ha NB, Fan B, Seetharaman S, Kent DS, Yao F, Shui AM, Huang CY, Wadhwani SI, Lai JC

Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.

Kidney medicine

Sheshadri A, Lai M, Hsu FC, Bauer SR, Chen SH, Tse W, Jotwani V, Tranah GJ, Lai JC, Hallan S, Fielding RA, Liu C, Ix JH, Coca SG, Shlipak MG

Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations.

Journal of Alzheimer's disease reports

Yu RC, Lai JC, Hui EK, Mukadam N, Kapur N, Stott J, Livingston G

Predicting Post-Liver Transplant Outcomes in Patients with Acute-on-Chronic Liver Failure using Expert-Augmented Machine Learning.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Ge J, Digitale JC, Fenton C, McCulloch CE, Lai JC, Pletcher MJ, Gennatas ED

Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States.

Journal of clinical gastroenterology

Wang M, Wadhwani SI, Cullaro G, Lai JC, Rubin JB

Brief PROMIS Assessment Screens for Frailty and Predicts Hospitalizations in Liver Transplant Candidates.

Transplantation

Thuluvath AJ, Duarte-Rojo A, Lai JC, Peipert J, Dietch ZC, Siddiqui O, Morrissey S, Belfanti K, Zhao L, Guo K, Nizamuddin M, Polineni P, Levitsky J, Flores AM, Ladner DP

Reply: What is the actual role of decompensated cirrhosis in the breakthrough SARS-CoV-2 infection?

Hepatology (Baltimore, Md.)

Ge J, Digitale JC, Pletcher MJ, Lai JC, N3C Consortium

Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.

medRxiv : the preprint server for health sciences

Klepper A, Kung A, Vazquez SE, Mitchell A, Mann S, Zorn K, Avila-Vargas I, Kari S, Tekeste M, Castro J, Lee B, Duarte M, Khalili M, Yang M, Wolters P, Price J, Perito E, Feng S, Maher JJ, Lai J, Weiler-Normann C, Lohse AW, DeRisi J, Tana M

Caregiver Burden in Adult Solid Organ Transplantation.

Transplantation

Deng LX, Sharma A, Gedallovich SM, Tandon P, Hansen L, Lai JC

Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation.

Journal of clinical gastroenterology

Wang M, Ge J, Ha N, Shui AM, Huang CY, Cullaro G, Lai JC

Early Liver Specialist Consultation is Associated With Faster Biochemical Resolution of Severe Immune Checkpoint Inhibitor-Induced Hepatitis.

Journal of the National Comprehensive Cancer Network : JNCCN

Li M, Wong D, Sack JS, Vogel AS, Hodi FS, Fong L, Lai JC, Grover S, Zucker SD

Targets and study design for symptom-focused trials aimed at patients with cirrhosis: An expert consensus.

Hepatology communications

Patel AA, Tapper EB, Kanwal F, Woodrell CD, Hansen L, Lai JC, Rogal S, McDermott C, Rakoski M, Ufere NN

Change in Platelet Count After Transjugular Intrahepatic Portosystemic Shunt Creation: An Advancing Liver Therapeutic Approaches (ALTA) Group Study.

Journal of vascular and interventional radiology : JVIR

Wong RJ, Ge J, Boike J, German M, Morelli G, Spengler E, Said A, Desai A, Couri T, Paul S, Frenette C, Verna EC, Goel A, Fallon M, Thornburg B, VanWagner L, Lai JC, Kolli KP

Actionable Solutions to Achieve Health Equity in Chronic Liver Disease.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Jones PD, Lai JC, Bajaj JS, Kanwal F

The TeLeFI (Tele-Liver Frailty Index): Development of a novel frailty tool in patients with cirrhosis via telemedicine.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Wang M, Shui AM, Barry F, Verna E, Kent D, Yao F, Seetharaman S, Berry K, Grubbs RK, George G, Huang CY, Duarte-Rojo A, Lai JC

Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ha NB, Seetharaman S, Kent DS, Yao F, Shui AM, Huang CY, Walston J, Lai JC

Women with cirrhosis have lower self-rated health than men.

Hepatology communications

Wang M, Huang CY, Cullaro G, Covinsky K, Lai JC

Association of Frailty With Health-Related Quality of Life in Liver Transplant Recipients.

JAMA surgery

Lai JC, Shui AM, Duarte-Rojo A, Rahimi RS, Ganger DR, Verna EC, Volk ML, Kappus M, Ladner DP, Boyarsky B, Segev DL, Gao Y, Huang CY, Singer JP

Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Ufere NN, El-Jawahri A, Ritchie C, Lai JC, Schwarze ML

The impact of right atrial pressure on outcomes in patients undergoing TIPS, An ALTA group study.

Hepatology (Baltimore, Md.)

Bommena S, Mahmud N, Boike JR, Thornburg BG, Kolli KP, Lai JC, German M, Morelli G, Spengler E, Said A, Desai AP, Junna S, Paul S, Frenette C, Verna EC, Goel A, Gregory D, Padilla C, VanWagner LB, Fallon MB, Advancing Liver Therapeutic Approaches (ALTA) Study Group

Introducing Norah Terrault, MD, MPH, Our 2023 AASLD President.

Hepatology (Baltimore, Md.)

Peters MG, Lai JC

Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Sawinski D, Lai JC, Pinney S, Gray AL, Jackson AM, Stewart D, Levine DJ, Locke JE, Pomposelli JJ, Hartwig MG, Hall SA, Dadhania DM, Cogswell R, Perez RV, Schold JD, Turgeon NA, Kobashigawa J, Kukreja J, Magee JC, Friedewald J, Gill JS, Loor G, Heimbach JK, Verna EC, Walsh MN, Terrault N, Testa G, Diamond JM, Reese PP, Brown K, Orloff S, Farr MA, Olthoff KM, Siegler M, Ascher N, Feng S, Kaplan B, Pomfret E

CT-quantified sarcopenic visceral obesity is associated with poor transplant waitlist mortality in patients with cirrhosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ha NB, Fan B, Shui AM, Huang CY, Brandman D, Lai JC

Cirrhosis Inpatients Receive More Opioids and Fewer Nonopioid Analgesics Than Patients Without Cirrhosis.

Journal of clinical gastroenterology

Rubin JB, Lai JC, Shui AM, Hohmann SF, Auerbach A

Multicenter Assessment of Hypertension Management of Liver Transplant Recipients.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Chebrolu S, Phipps M, Yao F, Lai J, Verna E, Serper M, Cullaro G, Asrani SK, VanWagner LB

Response to: "Towards optimally replacing the current version of MELD".

Journal of hepatology

Ge J, Kim WR, Lai JC, Kwong AJ

Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium.

Transplantation direct

Barman PM, Patel YA, Xie J, Zhang M, Jo J, Sinha J, Answine A, Schluger A, Walter K, Biggins SW, Cullaro G, Wong R, Lai JC, VanWagner LB, Magee J, Verna EC, Sharma P

Role of Oral Health, Frailty, and Minimal Hepatic Encephalopathy in the Risk of Hospitalization: A Prospective Multi-Center Cohort of Outpatients With Cirrhosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Bajaj JS, Lai JC, Tandon P, O'Leary JG, Wong F, Garcia-Tsao G, Vargas HE, Kamath PS, Biggins SW, Limon-Miro A, Shaw J, Mbachi C, Chew M, Golob Deeb J, Thacker LR, Reddy KR

Factors associated with cardiovascular events after simultaneous liver-kidney transplant from the US Multicenter Simultaneous Liver-Kidney Transplant Consortium.

Hepatology communications

Jo J, Crespo G, Gregory D, Sinha J, Xie J, Zhang M, Magee J, Barman P, Patel YA, Schluger A, Walters K, Biggins S, Filipek N, Cullaro G, Wong R, Lai JC, Perreault GJ, Verna EC, Sharma P, VanWagner LB

Personality Traits in Patients With Cirrhosis Are Different From Those of the General Population and Impact Likelihood of Liver Transplantation.

Transplantation

Thuluvath AJ, Siddiqui O, Lai JC, Peipert J, Levitsky J, Daud A, Mazumder NR, Flores AM, Borja-Cacho D, Caicedo JC, Loftus C, Wong R, Mroczek D, Ladner DP

Leveraging a New ICD-10 Diagnosis Code to Characterize Hospitalized Patients With Primary Sclerosing Cholangitis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Wang M, Auerbach A, Oreper SM, Hohmann SF, Lai JC, Rubin JB

Association of serum metabolites and gut microbiota at hospital admission with nosocomial infection development in patients with cirrhosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Bajaj JS, Reddy KR, Tandon P, Garcia-Tsao G, Kamath PS, O'Leary JG, Wong F, Lai J, Vargas H, Thuluvath PJ, Subramanian RM, Pena-Rodriguez M, Sikaroodi M, Thacker LR, Gillevet PM

Novel approaches are needed to study social determinants of health in liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ge J, Lai JC, Wadhwani SI

Medical Need and Transplant Accessibility-Reply.

JAMA

Wadhwani SI, Lai JC, Gottlieb L

Hepatic and renal function impact concentrations of plasma biomarkers of neuropathology.

Alzheimer's & dementia (Amsterdam, Netherlands)

Berry K, Asken BM, Grab JD, Chan B, Lario Lago A, Wong R, Seetharaman S, LaHue SC, Possin KL, Rojas JC, Kramer JH, Boxer AL, Lai JC, VandeVrede L

Breakthrough SARS-CoV-2 Infection Outcomes in Vaccinated Patients with Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.

medRxiv : the preprint server for health sciences

Ge J, Digitale JC, Pletcher MJ, Lai JC, N3C Consortium

Financial Burden in Adults with Chronic Liver Disease: A Scoping Review.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ufere NN, Satapathy N, Philpotts L, Lai JC, Serper M

Burden of Early Hospitalization after Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter SLKT Consortium.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Sharma P, Xie J, Wang L, Zhang M, Magee J, Answine A, Barman P, Jo J, Sinha J, Schluger A, Perreault GJ, Walters K, Cullaro G, Wong R, Filipek N, Biggins SW, Lai JC, VanWagner LB, Verna EC, Patel YA

The Digital Determinants of Liver Disease.

Hepatology (Baltimore, Md.)

Wadhwani SI, Lai JC

Caregiver perspectives on the everyday medical and social needs of long-term pediatric liver transplant patients.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Wadhwani SI, Barrera AG, Shifman HP, Baker E, Bucuvalas J, Gottlieb LM, Kotagal U, Rhee SJ, Lai JC, Lyles CR

Conceptualizing a Traditional Chinese Medicine and Pathology of Arousal Diagnostic and Pathophysiological Framework for Postacute Sequelae of COVID-19.

Medical acupuncture

Calloway T, Hsiao AF, Brand M, Lai J, Geise C, Caceido B, Alpert R, Hollifield M

Improvement in Long-COVID Symptoms Using Acupuncture: A Case Study.

Medical acupuncture

Hollifield M, Cocozza K, Calloway T, Lai J, Caicedo B, Carrick K, Alpert R, Hsiao AF

Sarcopenic visceral obesity is associated with increased post-liver transplant mortality in acutely ill patients with cirrhosis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Ha NB, Montano-Loza AJ, Carey EJ, Lin S, Shui AM, Huang CY, Dunn MA, Lai JC

Loneliness in adults awaiting liver transplantation at 7 U.S. transplant centers.

Annals of hepatology

Berry KA, Kent D, Seetharaman S, Wong R, Mohamad Y, Yao F, Nunez-Duarte M, Wadhwani SI, Boyarsky BJ, Rahimi RS, Duarte-Rojo A, Kappus MR, Volk ML, Ladner DP, Segev DL, McAdams-DeMarco M, Verna EC, Ganger DR, Lai JC

A review of racial, socioeconomic, and geographic disparities in pediatric liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ebel NH, Lai JC, Bucuvalas JC, Wadhwani SI

Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multi-center Inpatient Cirrhosis Cohort.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Bajaj JS, Tandon P, O'Leary JG, Reddy KR, Garcia-Tsao G, Thuluvath P, Lai JC, Subramanian RM, Vargas HE, Wong F, Fagan A, McGeorge S, Thacker LR, Kamath PS

Improving the model for end-stage liver disease with sodium by incorporating kidney dysfunction types.

Hepatology (Baltimore, Md.)

Cullaro G, Verna EC, McCulloch CE, Lai JC

GUIDELINE TO PRACTICE: ACUTE ON CHRONIC LIVER FAILURE.

The American journal of gastroenterology

Bajaj JS, Wong F, Kamath PS, Lai JC, O'Leary JG

Association of Primary Care Shortage Areas with Adverse Outcomes After Pediatric Liver Transplant.

The Journal of pediatrics

Shifman HP, Rasnick E, Huang CY, Beck AF, Bucuvalas J, Lai JC, Wadhwani SI

Top Ten Tips Palliative Care Clinicians Should Know About Solid Organ Transplantation.

Journal of palliative medicine

Murakami N, Baggett ND, Schwarze ML, Ladin K, Courtwright AM, Goldberg HJ, Nolley EP, Jain N, Landzberg M, Wentlandt K, Lai JC, Shinall MC, Ufere NN, Jones CA, Lakin JR

Implicit bias and the gender inequity in liver transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Pomfret EA, Verna EC

Acute-on-Chronic Liver Failure Clinical Guidelines.

The American journal of gastroenterology

Bajaj JS, O'Leary JG, Lai JC, Wong F, Long MD, Wong RJ, Kamath PS

Prognosis of hospitalized patients with cirrhosis and acute kidney disease.

Liver international : official journal of the International Association for the Study of the Liver

Wong F, Garcia-Tsao G, Reddy KR, O'Leary JG, Kamath PS, Tandon P, Lai JC, Vargas HE, Biggins SW, Fallon MB, Thuluvath PJ, Maliakkal BJ, Subramanian R, Thacker L, Bajaj JS

Response to: Relevance of Population-Based Cut-offs to Define Frailty in Clinical Studies.

Hepatology (Baltimore, Md.)

Wang S, Whitlock R, Lai JC, Taneja S, Tandon P

Long-Term Opioid Use Among Veterans with Cirrhosis: High-Dose Prescriptions in an Exceedingly High-Risk Population.

Journal of general internal medicine

Rubin JB, Lai JC, Leonard S, Seal K, Hoggatt KJ, Keyhani S

Frailty, Mortality, and Healthcare Utilization after Liver Transplantation: From the Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study.

Hepatology (Baltimore, Md.)

Lai JC, Shui AM, Duarte-Rojo A, Ganger DR, Rahimi RS, Huang CY, Yao F, Kappus M, Boyarsky B, McAdams-Demarco M, Volk ML, Dunn MA, Ladner DP, Segev DL, Verna EC, Feng S, Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study

Racial/Ethnic Disparities in Wait List Outcomes Are Only Partly Explained by Socioeconomic Deprivation Among Children Awaiting Liver Transplantation.

Hepatology (Baltimore, Md.)

Wadhwani SI, Ge J, Gottlieb L, Lyles C, Beck AF, Bucuvalas J, Neuhaus J, Kotagal U, Lai JC

Frailty is associated with increased risk of cirrhosis disease progression and death.

Hepatology (Baltimore, Md.)

Wang S, Whitlock R, Xu C, Taneja S, Singh S, Abraldes JG, Burak KW, Bailey RJ, Lai JC, Tandon P

Frailty is strongly associated with self-reported symptom burden among patients with cirrhosis.

European journal of gastroenterology & hepatology

Deng LX, Bischoff KE, Kent DS, O'Riordan DL, Pantilat SZ, Lai JC

The Prediction of in-Hospital Mortality in Decompensated Cirrhosis with Acute-on-Chronic Liver Failure.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Wong F, Reddy KR, Tandon P, Lai JC, Jagarlamudi N, Weir V, Kok B, Kalainy S, Srisengfa YT, Albhaisi S, Reuter B, Acharya C, Shaw J, Thacker LR, Bajaj JS

Sex-Based Disparities in Hepatocellular Carcinoma Recurrence After Liver Transplantation.

Transplantation

Cullaro G, Rubin J, Mehta N, Yao F, Verna EC, Lai JC

Pilot Randomized Controlled Trial of an Advance Care Planning Video Decision Tool for Patients With Advanced Liver Disease.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Ufere NN, Robinson B, Donlan J, Indriolo T, Bloom J, Scherrer A, Mason NM, Patel A, Lai JC, Chung RT, Volandes A, El-Jawahri A

Frailty and the Risk of Acute Kidney Injury Among Patients With Cirrhosis.

Hepatology communications

Cullaro G, Verna EC, Duarte-Rojo A, Kappus MR, Ganger DR, Rahimi RS, Boyarsky B, Segev DL, McAdams-DeMarco M, Ladner DP, Volk ML, Hsu CY, Lai JC

Frailty and Risk of Serious Infections in Biologic-treated Patients With Inflammatory Bowel Diseases.

Inflammatory bowel diseases

Singh S, Heien HC, Sangaralingham L, Shah ND, Lai JC, Sandborn WJ, Moore AA

Addressing Social Adversity to Improve Outcomes for Children After Liver Transplant.

Hepatology (Baltimore, Md.)

Wadhwani SI, Gottlieb L, Bucuvalas JC, Lyles C, Lai JC

Outcomes After TIPS for Ascites and Variceal Bleeding in a Contemporary Era-An ALTA Group Study.

The American journal of gastroenterology

Boike JR, Mazumder NR, Kolli KP, Ge J, German M, Jest N, Morelli G, Spengler E, Said A, Lai JC, Desai AP, Couri T, Paul S, Frenette C, Verna EC, Rahim U, Goel A, Gregory D, Thornburg B, VanWagner LB, Advancing Liver Therapeutic Approaches (ALTA) Study Group

Thinking Ahead: Advance Care Planning for Patients With Cirrhosis.

Clinical liver disease

Deng LX, Tana MM, Lai JC

Correcting the sex disparity in access to liver transplantation: Lest perfect be the enemy of better.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Kwong AJ, Lai JC, Kim WR

Cognitive Impairment and Physical Frailty in Patients With Cirrhosis.

Hepatology communications

Berry K, Duarte-Rojo A, Grab JD, Dunn MA, Boyarsky BJ, Verna EC, Kappus MR, Volk ML, McAdams-DeMarco M, Segev DL, Ganger DR, Ladner DP, Shui A, Tincopa MA, Rahimi RS, Lai JC, from the Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study

Temporal Trends and Evolving Outcomes After Simultaneous Liver-Kidney Transplantation (SLKT): Results from the US SLKT Consortium.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Cullaro G, Sharma P, Jo J, Rassiwala J, VanWagner LB, Wong R, Lai JC, Magee J, Schluger A, Barman P, Patel YA, Walter K, Biggins SW, Verna EC

Symptom Burden Is Associated with Increased Emergency Department Utilization among Patients with Cirrhosis.

Journal of palliative medicine

Deng LX, Kent DS, O'Riordan DL, Pantilat SZ, Lai JC, Bischoff KE

Inpatient Frailty Assessment Is Feasible and Predicts Nonhome Discharge and Mortality in Decompensated Cirrhosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Serper M, Tao SY, Kent DS, Garren P, Burdzy AE, Lai JC, Gougol A, Bloomer PM, Reddy KR, Dunn MA, Duarte-Rojo A

Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis.

Digestive diseases and sciences

Cullaro G, Rubin JB, Fortune BE, Crawford CV, Verna EC, Hsu CY, Liu KD, Brown RS, Lai JC, Rosenblatt R

The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.

Liver international : official journal of the International Association for the Study of the Liver

Xu CQ, Mohamad Y, Kappus MR, Boyarsky B, Ganger DR, Volk ML, Rahimi RS, Duarte-Rojo A, McAdams-DeMarco M, Segev DL, Ladner DP, Verna EC, Grab J, Tincopa M, Dunn MA, Lai JC

Admission Urinary and Serum Metabolites Predict Renal Outcomes in Hospitalized Patients With Cirrhosis.

Hepatology (Baltimore, Md.)

Bajaj JS, Garcia-Tsao G, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Subramanian RM, Thuluvath P, Fagan A, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Wong F

Sarcopenia and frailty in decompensated cirrhosis.

Journal of hepatology

Tandon P, Montano-Loza AJ, Lai JC, Dasarathy S, Merli M

Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach.

Hepatology communications

Patel AA, Woodrell C, Ufere NN, Hansen L, Tandon P, Verma M, Lai J, Pinotti R, Rakoski M, Palliative Care Education, Advocacy, and Research in Liver Disease (PEARL) Workgroup and the AASLD P

Visceral Adipose Tissue Inflammation and Radiographic Visceral-to-Subcutaneous Adipose Tissue Ratio in Patients with Cirrhosis.

Digestive diseases and sciences

Ha NB, Cho SJ, Mohamad Y, Kent D, Jun G, Wong R, Swarnakar V, Lin S, Maher JJ, Lai JC

Outcomes of SARS-CoV-2 Infection in Patients with Chronic Liver Disease and Cirrhosis: a N3C Study.

medRxiv : the preprint server for health sciences

Ge J, Pletcher MJ, Lai JC, N3C Consortium

Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention.

American journal of nephrology

Sheshadri A, Kittiskulnam P, Delgado C, Sudore RL, Lai JC, Johansen KL

Renal Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter Simultaneous Liver-Kidney Transplantation Consortium.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Sharma P, Sui Z, Zhang M, Magee JC, Barman P, Patel Y, Schluger A, Walter K, Biggins SW, Cullaro G, Wong R, Lai JC, Jo J, Sinha J, VanWagner L, Verna EC

A Multicenter Pilot Randomized Clinical Trial of a Home-Based Exercise Program for Patients With Cirrhosis: The Strength Training Intervention (STRIVE).

The American journal of gastroenterology

Lai JC, Dodge JL, Kappus MR, Wong R, Mohamad Y, Segev DL, McAdams-DeMarco M

Center variation in long-term outcomes for socioeconomically deprived children.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Wadhwani SI, Huang CY, Gottlieb L, Beck AF, Bucuvalas J, Kotagal U, Lyles C, Lai JC

Renal Recovery and Mortality Risk among Patients with Hepatorenal Syndrome Receiving Chronic Maintenance Dialysis.

Kidney360

McAllister S, Lai JC, Copeland TP, Johansen KL, McCulloch CE, Kwong YD, Seth D, Grimes B, Ku E

Association of Frailty and Sex With Wait List Mortality in Liver Transplant Candidates in the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.

JAMA surgery

Lai JC, Ganger DR, Volk ML, Dodge JL, Dunn MA, Duarte-Rojo A, Kappus MR, Rahimi RS, Ladner DP, Boyarsky B, McAdams-DeMarco M, Segev DL, McCulloch CE, Verna EC

Implementing a Height-Based Rule for the Allocation of Pediatric Donor Livers to Adults: A Liver Simulated Allocation Model Study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ge J, Wood N, Segev D, Lai JC, Gentry S

Low Predictability of Readmissions and Death Using Machine Learning in Cirrhosis.

The American journal of gastroenterology

Hu C, Anjur V, Saboo K, Reddy KR, O'Leary J, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Lai JC, Biggins SW, Fallon MB, Thuluvath P, Subramanian RM, Maliakkal B, Vargas H, Thacker LR, Iyer RK, Bajaj JS

Evaluating the Associations Between the Liver Frailty Index and Karnofsky Performance Status With Waitlist Mortality.

Transplantation direct

Xu CQ, Yao F, Mohamad Y, Wong R, Kent D, Seetharaman S, Srisengfa Y, Lai JC

National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction.

Hepatology communications

Kriss M, Te HS, Verna EC, VanWagner LB, Scott FI, Lai JC

Nonalcoholic Fatty Liver Disease and Diabetes Mellitus Are Associated With Post-Transjugular Intrahepatic Portosystemic Shunt Renal Dysfunction: An Advancing Liver Therapeutic Approaches Group Study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ge J, Lai JC, Boike JR, German M, Jest N, Morelli G, Spengler E, Said A, Lee A, Hristov A, Desai AP, Junna S, Pokhrel B, Couri T, Paul S, Frenette C, Christian-Miller N, Laurito M, Verna EC, Rahim U, Goel A, Das A, Pine S, Gregory D, VanWagner LB, Kolli KP, Advancing Liver Therapeutic Approaches (ALTA) Study Group

Increased Risk of ACLF and Inpatient Mortality in Hospitalized Patients with Cirrhosis and Hepatic Hydrothorax.

Digestive diseases and sciences

O'Leary JG, Rajender Reddy K, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Bajaj JS

Kefir Peptides Prevent Estrogen Deficiency-Induced Bone Loss and Modulate the Structure of the Gut Microbiota in Ovariectomized Mice.

Nutrients

Tu MY, Han KY, Chang GR, Lai GD, Chang KY, Chen CF, Lai JC, Lai CY, Chen HL, Chen CM

Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates.

Hepatology (Baltimore, Md.)

Kardashian A, Ge J, McCulloch CE, Kappus MR, Dunn MA, Duarte-Rojo A, Volk ML, Rahimi RS, Verna EC, Ganger DR, Ladner D, Dodge JL, Boyarsky B, McAdams-DeMarco M, Segev DL, Lai JC

Outcomes of Liver Transplantation Among Older Recipients With Nonalcoholic Steatohepatitis in a Large Multicenter US Cohort: the Re-Evaluating Age Limits in Transplantation Consortium.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Kwong AJ, Devuni D, Wang C, Boike J, Jo J, VanWagner L, Serper M, Jones L, Sharma R, Verna EC, Shor J, German MN, Hristov A, Lee A, Spengler E, Koteish AA, Sehmbey G, Seetharam A, John N, Patel Y, Kappus MR, Couri T, Paul S, Salgia RJ, Nhu Q, Frenette CT, Lai JC, Goel A, Re-Evaluating Age Limits in Transplantation (REALT) Consortium

Unforeseen consequences of the COVID pandemic.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Bucuvalas J, Lai JC

Progression of Stage 2 and 3 Acute Kidney Injury in Patients With Decompensated Cirrhosis and Ascites.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Wong F, Reddy KR, Tandon P, O'Leary JG, Garcia-Tsao G, Vargas HE, Lai JC, Biggins SW, Maliakkal B, Fallon M, Subramanian R, Thuluvath P, Kamath PS, Thacker L, Bajaj JS

Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Wadhwani SI, Brokamp C, Rasnick E, Bucuvalas JC, Lai JC, Beck AF

Association of motivations and barriers with participation and performance in a pedometer-based intervention.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Sheshadri A, Kittiskulnam P, Delgado C, Sudore R, Lai JC, Johansen KL

Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Wong RJ, Mohamad Y, Srisengfa YT, Kent DS, Seetharaman S, Shah RJ, Lai JC

Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis.

Gastroenterology

Bajaj JS, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Wong F, Subramanian RM, Thuluvath P, Fagan A, White MB, Gavis EA, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Sikaroodi M, Garcia-Tsao G, Gillevet PM

Liver Transplant Survivorship.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Lai JC, Ufere NN, Bucuvalas JC

Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates.

Annals of surgery

Haugen CE, McAdams-DeMarco M, Holscher CM, Ying H, Gurakar AO, Garonzik-Wang J, Cameron AM, Segev DL, Lai JC

Aggressive utilization of liver allografts: Improved outcomes over time.

Clinical transplantation

Rana A, Price MB, Barrett SC, Lai J, Bakhtiyar SS, Kanwal F, Vierling J, Wu M, Galvan NT, Goss J

Women who undergo liver transplant have longer length of stay post-transplant compared with men.

Liver international : official journal of the International Association for the Study of the Liver

Rubin JB, Cullaro G, Ge J, Lai JC

Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Bajaj JS, O'Leary JG, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Lai J, Fallon MB, Thuluvath PJ, Vargas HE, Maliakkal B, Subramanian RM, Thacker LR, Reddy KR

Physical Function, Physical Activity, and Quality of Life After Liver Transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Dunn MA, Rogal SS, Duarte-Rojo A, Lai JC

Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Cullaro G, Verna EC, Lee BP, Lai JC

Changes in frailty are associated with waitlist mortality in patients with cirrhosis.

Journal of hepatology

Lai JC, Dodge JL, Kappus MR, Dunn MA, Volk ML, Duarte-Rojo A, Ganger DR, Rahimi RS, McCulloch CE, Haugen CE, McAdams-DeMarco M, Ladner DP, Segev DL, Verna EC, Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study

Underutilization of Hospice in Inpatients with Cirrhosis: The NACSELD Experience.

Digestive diseases and sciences

O'Leary JG, Tandon P, Reddy KR, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Bajaj JS

Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Wadhwani SI, Beck AF, Bucuvalas J, Gottlieb L, Kotagal U, Lai JC

Frailty Is Associated With Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Fozouni L, Mohamad Y, Lebsack A, Freise C, Stock P, Lai JC

A Comprehensive Review of Outcome Predictors in Low MELD Patients.

Transplantation

Mazumder NR, Atiemo K, Kappus M, Cullaro G, Harinstein ME, Ladner D, Verna E, Lai J, Levitsky J

Response to "Reply to: 'The decreasing predictive power of MELD in an era of changing etiology of liver disease'".

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A

Gender Differences Among Patients Hospitalized With Cirrhosis in the United States.

Journal of clinical gastroenterology

Rubin JB, Sundaram V, Lai JC

Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Ge J, Perito ER, Bucuvalas J, Gilroy R, Hsu EK, Roberts JP, Lai JC

Association Between Liver Transplant Wait-list Mortality and Frailty Based on Body Mass Index.

JAMA surgery

Haugen CE, McAdams-DeMarco M, Verna EC, Rahimi RS, Kappus MR, Dunn MA, Volk ML, Gurakar A, Duarte-Rojo A, Ganger DR, O'Leary JG, Ladner D, Garonzik-Wang J, Segev DL, Lai JC

Sex Differences in the Association Between Frailty and Sarcopenia in Patients With Cirrhosis.

Clinical and translational gastroenterology

Fozouni L, Wang CW, Lai JC

Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Cullaro G, Rubin JB, Mehta N, Lai JC

Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Ge J, Lai JC

Sarcopenia Predicts Post-transplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation.

Transplantation

Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC

Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study.

Hepatology communications

Lai JC, Dodge JL, McCulloch CE, Covinsky KE, Singer JP

Hospitalized Women With Cirrhosis Have More Nonhepatic Comorbidities and Associated Complications Than Men.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Rubin JB, Srisengfa YT, Albhaisi S, Acharya C, Nangia G, Shaikh T, Thacker LR, Reddy KR, Tandon P, Bajaj JS, Lai JC

Review article: impact of exercise on physical frailty in patients with chronic liver disease.

Alimentary pharmacology & therapeutics

Williams FR, Berzigotti A, Lord JM, Lai JC, Armstrong MJ

The decreasing predictive power of MELD in an era of changing etiology of liver disease.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A

A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation.

Hepatology (Baltimore, Md.)

Carey EJ, Lai JC, Sonnenday C, Tapper EB, Tandon P, Duarte-Rojo A, Dunn MA, Tsien C, Kallwitz ER, Ng V, Dasarathy S, Kappus M, Bashir MR, Montano-Loza AJ

Barriers to ideal outcomes after pediatric liver transplantation.

Pediatric transplantation

Ng VL, Mazariegos GV, Kelly B, Horslen S, McDiarmid SV, Magee JC, Loomes KM, Fischer RT, Sundaram SS, Lai JC, Te HS, Bucuvalas JC

Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis.

The American journal of gastroenterology

Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Biggins SW, Lai JC, Vargas HE, Maliakkal B, Fallon MB, Thuluvath PJ, Subramanian RM, Thacker LR, Reddy KR

Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Sonnenday CJ, Tapper EB, Duarte-Rojo A, Dunn MA, Bernal W, Carey EJ, Dasarathy S, Kamath BM, Kappus MR, Montano-Loza AJ, Nagai S, Tandon P

Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Ge J, Lai JC

Targets to improve quality of care for patients with hepatic encephalopathy: data from a multi-centre cohort.

Alimentary pharmacology & therapeutics

Bajaj JS, O'Leary JG, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Lai J, Fallon MB, Thuluvath PJ, Vargas HE, Maliakkal B, Subramanian RM, Thacker LR, Reddy KR

The Range and Reproducibility of the Liver Frailty Index.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Wang CW, Lebsack A, Chau S, Lai JC

Impact of Chronic Kidney Disease on Outcomes in Cirrhosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Wong F, Reddy KR, O'Leary JG, Tandon P, Biggins SW, Garcia-Tsao G, Maliakkal BJ, Lai JC, Fallon MB, Vargas HE, Subramanian R, Thuluvath PJ, Kamath PS, Thacker L, Bajaj JS

Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis.

The American journal of gastroenterology

Bajaj JS, Tandon P, O'Leary JG, Wong F, Biggins SW, Garcia-Tsao G, Kamath PS, Maliakkal B, Fallon MB, Lai JC, Thuluvath PJ, Vargas HE, Subramanian RM, Thacker LR, Reddy KR

Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

O'Leary JG, Bajaj JS, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Reddy KR

Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men.

World journal of gastroenterology

Rubin JB, Sinclair M, Rahimi RS, Tapper EB, Lai JC

Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation.

Hepatology (Baltimore, Md.)

Ge J, Hsu EK, Bucuvalas J, Lai JC

Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Cullaro G, Verna EC, Lai JC

Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study.

Gastroenterology

Lai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL

Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Perito ER, Bucuvalas J, Lai JC

Report from the American Society of Transplantation on frailty in solid organ transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Kobashigawa J, Dadhania D, Bhorade S, Adey D, Berger J, Bhat G, Budev M, Duarte-Rojo A, Dunn M, Hall S, Harhay MN, Johansen KL, Joseph S, Kennedy CC, Kransdorf E, Lentine KL, Lynch RJ, McAdams-DeMarco M, Nagai S, Olymbios M, Patel J, Pinney S, Schaenman J, Segev DL, Shah P, Singer LG, Singer JP, Sonnenday C, Tandon P, Tapper E, Tullius SG, Wilson M, Zamora M, Lai JC

Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection.

Journal of viral hepatitis

Sarkar M, Lai JC, Sawinski D, Zeigler TE, Cedars M, Forde KA

How I Approach It: Improving Nutritional Status in Patients With Cirrhosis.

The American journal of gastroenterology

Lai JC, Tandon P

Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis.

Journal of cachexia, sarcopenia and muscle

Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ, From the Fitness, Life Enhancement, and Exercise in Liver Transplantation (FLEXIT) Consortium

Acute-on-Chronic Liver Failure: Getting Ready for Prime Time?

Hepatology (Baltimore, Md.)

Bajaj JS, Moreau R, Kamath PS, Vargas HE, Arroyo V, Reddy KR, Szabo G, Tandon P, Olson J, Karvellas C, Gustot T, Lai JC, Wong F

Beta-blockers and physical frailty in patients with end-stage liver disease.

World journal of gastroenterology

Kuo SZ, Lizaola B, Hayssen H, Lai JC

Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation.

Digestive diseases and sciences

Chascsa DM, Lai JC, Dunn MA, Montano-Loza AJ, Kappus MR, Dasarathy S, Carey EJ

Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations.

The Journal of clinical endocrinology and metabolism

Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Holick M, Orwoll E, Nielson C, Kaufmann M, Jones G, Bouillon R, Lai J, Verotta D, Bikle D

Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Bajaj JS, Vargas HE, Reddy KR, Lai JC, O'Leary JG, Tandon P, Wong F, Mitrani R, White MB, Kelly M, Fagan A, Patil R, Sait S, Sikaroodi M, Thacker LR, Gillevet PM

People who experience seclusion in adult mental health inpatient services: An examination of health of the nation outcome scales scores.

International journal of mental health nursing

Jury A, Lai J, Tuason C, Koning A, Smith M, Boyd L, Swanson C, Fergusson D, Gruar A

The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.

The American journal of gastroenterology

Bajaj JS, Tandon P, O'Leary JG, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Thuluvath P, Vargas HE, Subramanian RM, Thacker LR, Reddy RK

Assessment of the spectrum of hepatic encephalopathy: A multicenter study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Reuter B, Walter K, Bissonnette J, Leise MD, Lai J, Tandon P, Kamath PS, Biggins SW, Rose CF, Wade JB, Bajaj JS

Reply.

Hepatology (Baltimore, Md.)

Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S

NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.

Hepatology (Baltimore, Md.)

O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS

Physical frailty after liver transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Segev DL, McCulloch CE, Covinsky KE, Dodge JL, Feng S

Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study.

Transplantation

Puchades L, Chau S, Dodson JA, Mohamad Y, Mustain R, Lebsack A, Aguilera V, Prieto M, Lai JC

Sex-based disparities in delisting for being "too sick" for liver transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Cullaro G, Sarkar M, Lai JC

Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.

The American journal of gastroenterology

Bajaj JS, Reddy RK, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, O'Leary JG

The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis.

The American journal of gastroenterology

Lai JC, Covinsky KE, McCulloch CE, Feng S

Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices.

Clinical transplantation

Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS

Liver Transplantation in the Obese Cirrhotic Patient.

Transplantation

Spengler EK, O'Leary JG, Te HS, Rogal S, Pillai AA, Al-Osaimi A, Desai A, Fleming JN, Ganger D, Seetharam A, Tsoulfas G, Montenovo M, Lai JC

Transplant for the very sick: No limitations in donor quality?

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

C Lai J

Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List.

Gastroenterology

Hsu EK, Shaffer ML, Gao L, Sonnenday C, Volk ML, Bucuvalas J, Lai JC

Development of a novel frailty index to predict mortality in patients with end-stage liver disease.

Hepatology (Baltimore, Md.)

Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S

A multicenter study to define sarcopenia in patients with end-stage liver disease.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Carey EJ, Lai JC, Wang CW, Dasarathy S, Lobach I, Montano-Loza AJ, Dunn MA, Fitness, Life Enhancement, and Exercise in Liver Transplantation Consortium

Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Samoylova ML, Covinsky KE, Haftek M, Kuo S, Roberts JP, Lai JC

Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist.

World journal of gastroenterology

Sinclair M, Poltavskiy E, Dodge JL, Lai JC

Clinical Liver Disease

A framework to determine when liver transplantation is futile.

Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis.

BMC medicine

Pavasini R, Guralnik J, Brown JC, di Bari M, Cesari M, Landi F, Vaes B, Legrand D, Verghese J, Wang C, Stenholm S, Ferrucci L, Lai JC, Bartes AA, Espaulella J, Ferrer M, Lim JY, Ensrud KE, Cawthon P, Turusheva A, Frolova E, Rolland Y, Lauwers V, Corsonello A, Kirk GD, Ferrari R, Volpato S, Campo G

Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy.

ACG case reports journal

Giard JM, Decker KA, Lai JC, Gill RM, Logan AC, Fix OK

Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Maliakkal B, Biggins SW, Thuluvath PJ, Fallon MB, Subramanian RM, Vargas HE, Lai J, Thacker LR, Reddy KR

Underutilization of palliative care services in the liver transplant population.

World journal of transplantation

Kathpalia P, Smith A, Lai JC

ABO-Nonidentical Liver Transplantation in the United States.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Roberts JP

Defining the threshold for too sick for transplant.

Current opinion in organ transplantation

Lai JC

Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation.

Liver international : official journal of the International Association for the Study of the Liver

Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge J, Roberts JP, Terrault NA, Feng S

Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Wang CW, Covinsky KE, Feng S, Hayssen H, Segev DL, Lai JC

Outcomes for liver transplant candidates listed with low model for end-stage liver disease score.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Kwong AJ, Lai JC, Dodge JL, Roberts JP

Decision support for organ offers in liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Volk ML, Goodrich N, Lai JC, Sonnenday C, Shedden K

Hepatitis C genotype influences post-liver transplant outcomes.

Transplantation

Campos-Varela I, Lai JC, Verna EC, O'Leary JG, Todd Stravitz R, Forman LM, Trotter JF, Brown RS, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)

Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction.

Liver international : official journal of the International Association for the Study of the Liver

Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB

Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation.

Liver international : official journal of the International Association for the Study of the Liver

Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge JL, Roberts JP, Terrault NA, Feng S

Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C.

Digestive diseases and sciences

Lai JC, Shoback DM, Zipperstein J, Lizaola B, Tseng S, Terrault NA

Role of delta-aminolevulinic acid in the symptoms of acute porphyria.

The American journal of medicine

Bissell DM, Lai JC, Meister RK, Blanc PD

The octogenarian donor: can the liver be "younger than stated age"?

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Covinsky K, Feng S

Expanded criteria donors.

Clinics in liver disease

Feng S, Lai JC

Frailty predicts waitlist mortality in liver transplant candidates.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Feng S, Terrault NA, Lizaola B, Hayssen H, Covinsky K

A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations.

The Journal of clinical endocrinology and metabolism

Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, Terrault NA, Stotland N, Bikle D

Variability in free 25(OH) vitamin D levels in clinical populations.

The Journal of steroid biochemistry and molecular biology

Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D

Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Kahn JG, Tavakol M, Peters MG, Roberts JP

Offer patterns of nationally placed livers by donation service area.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Lai JC, Feng S, Vittinghoff E, Roberts JP

Center competition and outcomes following liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Halldorson JB, Paarsch HJ, Dodge JL, Segre AM, Lai J, Roberts JP

Sudden onset vision loss in an 8-year-old female with McCune-Albright syndrome.

Pediatric dermatology

Kim D, Wysong A, Lai J, Alcorn DM, Benjamin LT

Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Saxena V, Lai JC, O'Leary JG, Verna EC, Brown RS, Stravitz RT, Trotter JF, Krishnan K, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients

Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Lai JC, O'Leary JG, Trotter JF, Verna EC, Brown RS, Stravitz RT, Duman JD, Forman LM, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)

Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Verna EC, Valadao R, Farrand E, Pichardo EM, Lai JC, Terrault NA, Brown RS

Patient, center and geographic characteristics of nationally placed livers.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Roberts JP, Vittinghoff E, Terrault NA, Feng S

Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Brandman D, Pingitore A, Lai JC, Roberts JP, Ferrell L, Bass NM, Terrault NA

Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men.

Hepatology (Baltimore, Md.)

Lai JC, Verna EC, Brown RS, O'Leary JG, Trotter JF, Forman LM, Duman JD, Foster RG, Stravitz RT, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)

Gender differences in liver donor quality are predictive of graft loss.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Feng S, Roberts JP, Terrault NA

Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Terrault NA, Vittinghoff E, Biggins SW

Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop.

The American journal of gastroenterology

Monto A, Schooley RT, Lai JC, Sulkowski MS, Chung RT, Pawlotsky JM, McHutchison JG, Jacobson IM

A novel housestaff educational model for quaternary-care patients at an academic health center.

Academic medicine : journal of the Association of American Medical Colleges

Lai JC, Montero A, Lebwohl B, Brown RS

Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lai JC, Pichardo EM, Emond JC, Brown RS

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