Linda Giudice, MD, PhD

Professor
Ob/Gyn, Reproductive Sciences
+1 415 502-4742

Linda C. Giudice, MD, PhD is Distinguished Professor, Chair Emerita, and the Robert B. Jaffe MD Endowed Professor in the Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco (UCSF). She is a biochemist and reproductive endocrinologist specializing in endometriosis and infertility. Her research focuses on human endometrial function and regeneration, genetics and epigenetics of endometriosis, placental-uterine interactions relevant to pregnancy outcomes, and evaluating the evidence of environmental impacts on reproductive health and human development. She has mentored over 250 students, fellows and faculty, authored > 300 peer-reviewed publications, and is co-editor of 6 textbooks on women’s health, reproductive environmental health, endocrinology, endometrium and endometriosis. She is Past-President of the American Society for Reproductive Medicine, the Society for Gynecologic Investigation, President of the World Endometriosis Society, President-elect of the International Federation of Fertility Societies, and Chair of the FIGO (International Federation of Gynecology and Obstetrics) Reproductive and Developmental Environmental Health Working Group. Dr. Giudice is on the UCSF Steering Committee on Women’s Precision Medicine, the March of Dimes Scientific Advisory Council, and is an elected member of the U.S. National Academy of Medicine and the U.S. National Academy of Inventors.

Publications: 

Identifying therapeutic candidates for endometriosis through a transcriptomics-based drug repositioning approach.

iScience

Oskotsky TT, Bhoja A, Bunis D, Le BL, Tang AS, Kosti I, Li C, Houshdaran S, Sen S, Vallvé-Juanico J, Wang W, Arthurs E, Govil A, Mahoney L, Lang L, Gaudilliere B, Stevenson DK, Irwin JC, Giudice LC, McAllister SL, Sirota M

Two-year efficacy and safety of relugolix combination therapy in women with endometriosis-associated pain: SPIRIT open-label extension study.

Human reproduction (Oxford, England)

Becker CM, Johnson NP, As-Sanie S, Arjona Ferreira JC, Abrao MS, Wilk K, Imm SJ, Mathur V, Perry JS, Wagman RB, Giudice LC

Time for global health policy and research leaders to prioritize endometriosis.

Nature communications

Giudice LC, Horne AW, Missmer SA

A Plain Language Summary to learn about relugolix combination therapy for the treatment of pain associated with endometriosis.

Pain management

Giudice LC, As-Sanie S, Arjona Ferreira JC, Becker CM, Abrao MS, Lessey BA, Dynowski K, Wilk K, Li Y, Mathur V, Wagman RB, Johnson NP

Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Giudice LC, Oskotsky TT, Falako S, Opoku-Anane J, Sirota M

Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function.

Communications biology

Mortlock S, Houshdaran S, Kosti I, Rahmioglu N, Nezhat C, Vitonis AF, Andrews SV, Grosjean P, Paranjpe M, Horne AW, Jacoby A, Lager J, Opoku-Anane J, Vo KC, Manvelyan E, Sen S, Ghukasyan Z, Collins F, Santamaria X, Saunders P, Kober K, McRae AF, Terry KL, Vallvé-Juanico J, Becker C, Rogers PAW, Irwin JC, Zondervan K, Montgomery GW, Missmer S, Sirota M, Giudice L

B-cell lymphoma 6 (BCL6) expression significantly differs by uterine preparation method used for frozen embryo transfer.

Fertility and sterility

Huang D, Chan M, Solomon M, Cedars MI, Giudice LC, Cakmak H

Leveraging electronic health records to identify risk factors for recurrent pregnancy loss across two medical centers: a case-control study.

Research square

Roger J, Xie F, Costello J, Tang A, Liu J, Oskotsky T, Woldemariam S, Kosti I, Le B, Snyder M, Giudice L, Torgerson D, Shaw G, Stevenson D, Rajkovic A, Aghaeepour N, Glymour M, Cakmak H, Lathi R, Sirota M

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions.

Nature genetics

Rahmioglu N, Mortlock S, Ghiasi M, M?ller PL, Stefansdottir L, Galarneau G, Turman C, Danning R, Law MH, Sapkota Y, Christofidou P, Skarp S, Giri A, Banasik K, Krassowski M, Lepamets M, Marciniak B, N?ukas M, Perro D, Sliz E, Sobalska-Kwapis M, Thorleifsson G, Topbas-Selcuki NF, Vitonis A, Westergaard D, Arnadottir R, Burgdorf KS, Campbell A, Cheuk CSK, Clementi C, Cook J, De Vivo I, DiVasta A, Dorien O, Donoghue JF, Edwards T, Fontanillas P, Fung JN, Geirsson RT, Girling JE, Harkki P, Harris HR, Healey M, Heikinheimo O, Holdsworth-Carson S, Hostettler IC, Houlden H, Houshdaran S, Irwin JC, Jarvelin MR, Kamatani Y, Kennedy SH, Kepka E, Kettunen J, Kubo M, Kulig B, Kurra V, Laivuori H, Laufer MR, Lindgren CM, MacGregor S, Mangino M, Martin NG, Matalliotaki C, Matalliotakis M, Murray AD, Ndungu A, Nezhat C, Olsen CM, Opoku-Anane J, Padmanabhan S, Paranjpe M, Peters M, Polak G, Porteous DJ, Rabban J, Rexrode KM, Romanowicz H, Saare M, Saavalainen L, Schork AJ, Sen S, Shafrir AL, Siewierska-G?rska A, Slomka M, Smith BH, Smolarz B, Szaflik T, Szyllo K, Takahashi A, Terry KL, Tomassetti C, Treloar SA, Vanhie A, Vincent K, Vo KC, Werring DJ, Zeggini E, Zervou MI, DBDS Genomic Consortium, FinnGen Study, FinnGen Endometriosis Taskforce, Celmatix Research Team, 23andMe Research Team, Adachi S, Buring JE, Ridker PM, D'Hooghe T, Goulielmos GN, Hapangama DK, Hayward C, Horne AW, Low SK, Martikainen H, Chasman DI, Rogers PAW, Saunders PT, Sirota M, Spector T, Strapagiel D, Tung JY, Whiteman DC, Giudice LC, Velez-Edwards DR, Uimari O, Kraft P, Salumets A, Nyholt DR, M?gi R, Stefansson K, Becker CM, Yurttas-Beim P, Steinthorsdottir V, Nyegaard M, Missmer SA, Montgomery GW, Morris AP, Zondervan KT

Systematic review of climate change effects on reproductive health.

Fertility and sterility

Segal TR, Giudice LC

Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2).

Lancet (London, England)

Giudice LC, As-Sanie S, Arjona Ferreira JC, Becker CM, Abrao MS, Lessey BA, Brown E, Dynowski K, Wilk K, Li Y, Mathur V, Warsi QA, Wagman RB, Johnson NP

Response to Boulicault et al. (2021) from women in the field.

Human fertility (Cambridge, England)

Gore AC, Giudice LC, Flaws JA, Hunt PA

Commentary on the climate crisis and Women's health: Time for action.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Giudice LC

Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.

Reproductive biomedicine online

Zhai J, Li S, Sen S, Vallvé-Juanico J, Irwin JC, Vo KC, Wan J, Du Y, Chen ZJ, Giudice LC

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.

Science (New York, N.Y.)

Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Pisco AO, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Crasta S, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kolluru S, Kong W, Kumar ME, Kuo AH, Leylek R, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Morri M, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Phansalkar R, Pisco AO, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Travaglini KJ, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Tan SY, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Detweiler AM, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, de Morree A, Olivieri JE, Park M, Pisco AO, Ravikumar N, Salzman J, Stanley G, Swift M, Tan M, Tan W, Tarashansky AJ, Vanheusden R, Vorperian SK, Wang P, Wang S, Xing G, Xu C, Yosef N, Alcántara-Hernández M, Antony J, Chan CKF, Chang CA, Colville A, Crasta S, Culver R, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Kershner AM, Kong W, Kumar ME, Kuo AH, Leylek R, Liu S, Loeb GB, Lu WJ, Maltzman JS, Metzger RJ, de Morree A, Neuhöfer P, Perez K, Phansalkar R, Qi Z, Rao P, Raquer-McKay H, Sasagawa K, Scott B, Sinha R, Song H, Spencer SP, Swarup A, Swift M, Travaglini KJ, Trimm E, Veizades S, Vijayakumar S, Wang B, Wang W, Winkler J, Xie J, Yung AR, Artandi SE, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Krasnow M, Kuo CS, Nguyen P, Quake SR, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wang B, Wu A, Wu SM, Wyss-Coray T

Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood.

BMC medicine

Vallvé-Juanico J, George AF, Sen S, Thomas R, Shin MG, Kushnoor D, Vásquez JJ, Vo KC, Irwin JC, Roan NR, Combes AJ, Giudice LC

Nutritional interventions to ameliorate the effect of endocrine disruptors on human reproductive health: A semi-structured review from FIGO.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Corbett GA, Lee S, Woodruff TJ, Hanson M, Hod M, Charlesworth AM, Giudice L, Conry J, McAuliffe FM, International Federation of Gynecology, Obstetrics (FIGO) Committee on Impact of Pregnancy on Long-t

Whole-Tissue Deconvolution and scRNAseq Analysis Identify Altered Endometrial Cellular Compositions and Functionality Associated With Endometriosis.

Frontiers in immunology

Bunis DG, Wang W, Vallvé-Juanico J, Houshdaran S, Sen S, Ben Soltane I, Kosti I, Vo KC, Irwin JC, Giudice LC, Sirota M

Climate change, women's health, and the role of obstetricians and gynecologists in leadership.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Giudice LC, Llamas-Clark EF, DeNicola N, Pandipati S, Zlatnik MG, Decena DCD, Woodruff TJ, Conry JA, FIGO Committee on Climate Change and Toxic Environmental Exposures

Environmental impact on reproductive health and risk mitigating strategies.

Current opinion in obstetrics & gynecology

Giudice LC

Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area.

Chemosphere

Velarde MC, Chan AFO, Sajo MEJV, Zakharevich I, Melamed J, Uy GLB, Teves JMY, Corachea AJM, Valparaiso AP, Macalindong SS, Cabaluna ND, Dofitas RB, Giudice LC, Gerona RR

In silico, in vitro and in vivo analysis identifies endometrial circadian clock genes in recurrent implantation failure.

The Journal of clinical endocrinology and metabolism

Zhai J, Li S, Hu J, Gao M, Sun Y, Chen ZJ, Giudice LC, Du Y

Endometrial function in women with polycystic ovary syndrome: a comprehensive review.

Human reproduction update

Palomba S, Piltonen TT, Giudice LC

Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection.

The New England journal of medicine

Page K, Melia MT, Veenhuis RT, Winter M, Rousseau KE, Massaccesi G, Osburn WO, Forman M, Thomas E, Thornton K, Wagner K, Vassilev V, Lin L, Lum PJ, Giudice LC, Stein E, Asher A, Chang S, Gorman R, Ghany MG, Liang TJ, Wierzbicki MR, Scarselli E, Nicosia A, Folgori A, Capone S, Cox AL

Could children born to mothers with COVID-19 be more prone to non-communicable diseases?

Acta paediatrica (Oslo, Norway : 1992)

Malamitsi-Puchner A, Briana DD, Giudice L, Di Renzo GC

Genetic risk factors for endometriosis near estrogen receptor 1 and co-expression of genes in this region in endometrium.

Molecular human reproduction

Marla S, Mortlock S, Houshdaran S, Fung J, McKinnon B, Holdsworth-Carson SJ, Girling JE, Rogers PAW, Giudice LC, Montgomery GW

Patterns of sex hormone receptor expression in stimulated endometrium from oocyte donors.

Human fertility (Cambridge, England)

Manvelyan E, Houshdaran S, Irwin JC, Giudice LC, Aghajanova L

Eye to the Future in Adenomyosis Research.

Seminars in reproductive medicine

Halvorson LM, Giudice LC, Stewart EA

Developing a core outcome set for future infertility research: an international consensus development study†  ‡.

Human reproduction (Oxford, England)

Duffy JMN, AlAhwany H, Bhattacharya S, Collura B, Curtis C, Evers JLH, Farquharson RG, Franik S, Giudice LC, Khalaf Y, Knijnenburg JML, Leeners B, Legro RS, Lensen S, Vazquez-Niebla JC, Mavrelos D, Mol BWJ, Niederberger C, Ng EHY, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Repping S, Sarris I, Simpson JL, Strandell A, Strawbridge C, Torrance HL, Vail A, van Wely M, Vercoe MA, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM

Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study†  ‡.

Human reproduction (Oxford, England)

Duffy JMN, Bhattacharya S, Bhattacharya S, Bofill M, Collura B, Curtis C, Evers JLH, Giudice LC, Farquharson RG, Franik S, Hickey M, Hull ML, Jordan V, Khalaf Y, Legro RS, Lensen S, Mavrelos D, Mol BW, Niederberger C, Ng EHY, Puscasiu L, Repping S, Sarris I, Showell M, Strandell A, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM

Top 10 priorities for future infertility research: an international consensus development study†  ‡.

Human reproduction (Oxford, England)

Duffy JMN, Adamson GD, Benson E, Bhattacharya S, Bhattacharya S, Bofill M, Brian K, Collura B, Curtis C, Evers JLH, Farquharson RG, Fincham A, Franik S, Giudice LC, Glanville E, Hickey M, Horne AW, Hull ML, Johnson NP, Jordan V, Khalaf Y, Knijnenburg JML, Legro RS, Lensen S, MacKenzie J, Mavrelos D, Mol BW, Morbeck DE, Nagels H, Ng EHY, Niederberger C, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Sadler L, Sarris I, Showell M, Stewart J, Strandell A, Strawbridge C, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Wong K, Wong TY, Farquhar CM

Developing a core outcome set for future infertility research: an international consensus development study.

Fertility and sterility

Duffy JMN, AlAhwany H, Bhattacharya S, Collura B, Curtis C, Evers JLH, Farquharson RG, Franik S, Giudice LC, Khalaf Y, Knijnenburg JML, Leeners B, Legro RS, Lensen S, Vazquez-Niebla JC, Mavrelos D, Mol BWJ, Niederberger C, Ng EHY, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Repping S, Sarris I, Simpson JL, Strandell A, Strawbridge C, Torrance HL, Vail A, van Wely M, Vercoe MA, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM

Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study.

Fertility and sterility

Duffy JMN, Bhattacharya S, Bhattacharya S, Bofill M, Collura B, Curtis C, Evers JLH, Giudice LC, Farquharson RG, Franik S, Hickey M, Hull ML, Jordan V, Khalaf Y, Legro RS, Lensen S, Mavrelos D, Mol BW, Niederberger C, Ng EHY, Puscasiu L, Repping S, Sarris I, Showell M, Strandell A, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Youssef MA, Farquhar CM

Top 10 priorities for future infertility research: an international consensus development study.

Fertility and sterility

Duffy JMN, Adamson GD, Benson E, Bhattacharya S, Bhattacharya S, Bofill M, Brian K, Collura B, Curtis C, Evers JLH, Farquharson RG, Fincham A, Franik S, Giudice LC, Glanville E, Hickey M, Horne AW, Hull ML, Johnson NP, Jordan V, Khalaf Y, Knijnenburg JML, Legro RS, Lensen S, MacKenzie J, Mavrelos D, Mol BW, Morbeck DE, Nagels H, Ng EHY, Niederberger C, Otter AS, Puscasiu L, Rautakallio-Hokkanen S, Sadler L, Sarris I, Showell M, Stewart J, Strandell A, Strawbridge C, Vail A, van Wely M, Vercoe M, Vuong NL, Wang AY, Wang R, Wilkinson J, Wong K, Wong TY, Farquhar CM

Cellular Origins of Endometriosis: Towards Novel Diagnostics and Therapeutics.

Seminars in reproductive medicine

Filby CE, Rombauts L, Montgomery GW, Giudice LC, Gargett CE

Adenomyosis: Mechanisms and Pathogenesis.

Seminars in reproductive medicine

Zhai J, Vannuccini S, Petraglia F, Giudice LC

Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNF-alpha.

Development (Cambridge, England)

Taylor SK, Houshdaran S, Robinson JF, Gormley MJ, Kwan EY, Kapidzic M, Schilling B, Giudice LC, Fisher SJ

The global impact of COVID-19 on infertility services.

Global reproductive health

Ory SJ, Miller KA, Horton M, Giudice L

m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis.

Frontiers in genetics

Zhai J, Li S, Sen S, Opoku-Anane J, Du Y, Chen ZJ, Giudice LC

HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread.

eLife

Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR

Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosae of HIV-infected women.

American journal of reproductive immunology (New York, N.Y. : 1989)

Shanmugasundaram U, Critchfield JW, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL

Author's Reply.

Journal of minimally invasive gynecology

Montgomery GW, Mortlock S, Giudice LC

Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome.

Scientific reports

Smith-McCune K, Thomas R, Averbach S, Seidman D, Takeda M, Houshdaran S, Giudice LC

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions.

International journal of molecular sciences

Houshdaran S, Chen JC, Vallvé-Juanico J, Balayan S, Vo KC, Smith-McCune K, Greenblatt RM, Irwin JC, Giudice LC

Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.

Human reproduction (Oxford, England)

George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR

A Pilot Cancer-Phenome Biobanking System in a Low-Resource Southeast Asian Setting: The Philippine General Hospital Biobank Experience.

Biopreservation and biobanking

Sajo MEJV, Teves JMY, Corachea AJM, Diaz LA, Chan AFO, Valparaiso AP, Dy Echo AVV, Macalindong SS, Uy GLB, Dofitas RB, Habana MAE, Gerona RR, Irwin JC, Giudice LC, Velarde MC

Should Genetics Now be Considered the Pre-eminent Etiological Factor in Endometriosis?

Journal of minimally invasive gynecology

Montgomery GW, Mortlock S, Giudice LC

25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility.

Fertility and sterility

Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV

Reprint of: Pathogenesis and pathophysiology of endometriosis.

Fertility and sterility

Burney RO, Giudice LC

The endometrial immune environment of women with endometriosis.

Human reproduction update

Vallvé-Juanico J, Houshdaran S, Giudice LC

Assessing research gaps and unmet needs in endometriosis.

American journal of obstetrics and gynecology

As-Sanie S, Black R, Giudice LC, Gray Valbrun T, Gupta J, Jones B, Laufer MR, Milspaw AT, Missmer SA, Norman A, Taylor RN, Wallace K, Williams Z, Yong PJ, Nebel RA

Clinical diagnosis of endometriosis: a call to action.

American journal of obstetrics and gynecology

Agarwal SK, Chapron C, Giudice LC, Laufer MR, Leyland N, Missmer SA, Singh SS, Taylor HS

Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma.

Biology of reproduction

Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR

Forty years of IVF.

Fertility and sterility

Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR

Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies.

Obstetrics and gynecology

Surrey E, Taylor HS, Giudice L, Lessey BA, Abrao MS, Archer DF, Diamond MP, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Singh SS, Rechberger T, Agarwal SK, Duan WR, Schwefel B, Thomas JW, Peloso PM, Ng J, Soliman AM, Chwalisz K

Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation.

Contemporary clinical trials

Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H

In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration.

Journal of assisted reproduction and genetics

Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice LC

Effects of noncavity-distorting fibroids on endometrial gene expression and function.

Biology of reproduction

Aghajanova L, Houshdaran S, Irwin JC, Giudice LC

Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium.

Biology of reproduction

Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice LC

Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers.

Scientific reports

Altmäe S, Koel M, Võsa U, Adler P, Suhorutšenko M, Laisk-Podar T, Kukushkina V, Saare M, Velthut-Meikas A, Krjutškov K, Aghajanova L, Lalitkumar PG, Gemzell-Danielsson K, Giudice L, Simón C, Salumets A

Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist.

The New England journal of medicine

Taylor HS, Giudice LC, Lessey BA, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel B, Thomas JW, Jain RI, Chwalisz K

New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity.

The New England journal of medicine

Montgomery GW, Giudice LC

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.

PLoS pathogens

Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR

Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility.

Mucosal immunology

Smith-McCune KK, Hilton JF, Shanmugasundaram U, Critchfield JW, Greenblatt RM, Seidman D, Averbach S, Giudice LC, Shacklett BL

World Endometriosis Society consensus on the classification of endometriosis.

Human reproduction (Oxford, England)

Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS, Bush D, Kiesel L, Tamimi R, Sharpe-Timms KL, Rombauts L, Giudice LC

Insights from imaging the implanting embryo and the uterine environment in three dimensions.

Development (Cambridge, England)

Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice LC, Laird DJ

Challenging dogma: the endometrium has a microbiome with functional consequences!

American journal of obstetrics and gynecology

Giudice LC

Research Priorities for Endometriosis.

Reproductive sciences (Thousand Oaks, Calif.)

Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, Saunders PT, Vincent K, Zondervan KT

Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis.

Biology of reproduction

Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice LC

Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium.

American journal of reproductive immunology (New York, N.Y. : 1989)

Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K

Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis.

Fertility and sterility

Aghajanova L, Altmäe S, Kasvandik S, Salumets A, Stavreus-Evers A, Giudice LC

Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis.

Reproductive sciences (Thousand Oaks, Calif.)

Herndon CN, Aghajanova L, Balayan S, Erikson D, Barragan F, Goldfien G, Vo KC, Hawkins S, Giudice LC

Moving from awareness to action on preventing patient exposure to toxic environmental chemicals.

American journal of obstetrics and gynecology

Sutton PM, Giudice LC, Woodruff TJ

Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis.

Biology of reproduction

Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice LC

Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity.

Fertility and sterility

Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC

International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Di Renzo GC, Conry JA, Blake J, DeFrancesco MS, DeNicola N, Martin JN, McCue KA, Richmond D, Shah A, Sutton P, Woodruff TJ, van der Poel SZ, Giudice LC

Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome.

Human reproduction update

Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice LC, Petraglia F

Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012".

Regulatory toxicology and pharmacology : RTP

Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT

Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study.

PloS one

Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC

Update on Biomarkers for the Detection of Endometriosis.

BioMed research international

Fassbender A, Burney RO, O DF, D'Hooghe T, Giudice L

Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal.

Human reproduction (Oxford, England)

Vercellini P, Giudice LC, Evers JL, Abrao MS

Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro.

Human reproduction (Oxford, England)

Piltonen TT, Chen JC, Khatun M, Kangasniemi M, Liakka A, Spitzer T, Tran N, Huddleston H, Irwin JC, Giudice LC

Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix.

Reproductive sciences (Thousand Oaks, Calif.)

Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC

Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals.

Journal of proteomics

Williams KE, Miroshnychenko O, Johansen EB, Niles RK, Sundaram R, Kannan K, Albertolle M, Zhou Y, Prasad N, Drake PM, Giudice LC, Hall SC, Witkowska HE, Buck Louis GM, Fisher SJ

Molecular classification of endometriosis and disease stage using high-dimensional genomic data.

Endocrinology

Tamaresis JS, Irwin JC, Goldfien GA, Rabban JT, Burney RO, Nezhat C, DePaolo LV, Giudice LC

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research.

Fertility and sterility

Fassbender A, Rahmioglu N, Vitonis AF, Viganò P, Giudice LC, D'Hooghe TM, Hummelshoj L, Adamson GD, Becker CM, Missmer SA, Zondervan KT

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research.

Fertility and sterility

Vitonis AF, Vincent K, Rahmioglu N, Fassbender A, Buck Louis GM, Hummelshoj L, Giudice LC, Stratton P, Adamson GD, Becker CM, Zondervan KT, Missmer SA

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research.

Fertility and sterility

Rahmioglu N, Fassbender A, Vitonis AF, Tworoger SS, Hummelshoj L, D'Hooghe TM, Adamson GD, Giudice LC, Becker CM, Zondervan KT, Missmer SA

Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation.

Molecular endocrinology (Baltimore, Md.)

Houshdaran S, Zelenko Z, Irwin JC, Giudice LC

Impact of surgical excision of lesions on pain in a rat model of endometriosis.

European journal of pain (London, England)

Alvarez P, Giudice LC, Levine JD

Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts.

Human reproduction (Oxford, England)

Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR

Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women.

American journal of reproductive immunology (New York, N.Y. : 1989)

Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL

Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium.

Human reproduction update

Altmäe S, Esteban FJ, Stavreus-Evers A, Simón C, Giudice L, Lessey BA, Horcajadas JA, Macklon NS, D'Hooghe T, Campoy C, Fauser BC, Salamonsen LA, Salumets A

Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors.

Environmental health : a global access science source

Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice LC, Iguchi T, Hass U, Jobling S, Juul A, Kidd KA, Kortenkamp A, Lind M, Martin OV, Muir D, Ochieng R, Olea N, Norrgren L, Ropstad E, Ross PS, Rudén C, Scheringer M, Skakkebaek NE, Söder O, Sonnenschein C, Soto A, Swan S, Toppari J, Tyler CR, Vandenberg LN, Vinggaard AM, Wiberg K, Zoeller RT

Elagolix, an Oral GnRH Antagonist for Endometriosis-Associated Pain: A Randomized Controlled Study.

Journal of endometriosis and pelvic pain disorders

Carr B, Giudice L, Dmowski WP, O'Brien C, Jiang P, Burke J, Jimenez R, Hass S, Fuldeore M, Chwalisz K

The human oviduct transcriptome reveals an anti-inflammatory, anti-angiogenic, secretory and matrix-stable environment during embryo transit.

Reproductive biomedicine online

Hess AP, Talbi S, Hamilton AE, Baston-Buest DM, Nyegaard M, Irwin JC, Barragan F, Kruessel JS, Germeyer A, Giudice LC

Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production.

Fertility and sterility

Chen JC, Erikson DW, Piltonen TT, Meyer MR, Barragan F, McIntire RH, Tamaresis JS, Vo KC, Giudice LC, Irwin JC

Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential.

The Journal of clinical endocrinology and metabolism

Piltonen TT, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC

Diversity of the vaginal microbiome correlates with preterm birth.

Reproductive sciences (Thousand Oaks, Calif.)

Hyman RW, Fukushima M, Jiang H, Fung E, Rand L, Johnson B, Vo KC, Caughey AB, Hilton JF, Davis RW, Giudice LC

Retrospective. Robert G. Edwards (1925-2013).

Science (New York, N.Y.)

Fisher SJ, Giudice LC

Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study.

Fertility and sterility

Buck Louis GM, Peterson CM, Chen Z, Croughan M, Sundaram R, Stanford J, Varner MW, Kennedy A, Giudice L, Fujimoto VY, Sun L, Wang L, Guo Y, Kannan K

Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis.

Biology of reproduction

Afshar Y, Hastings J, Roqueiro D, Jeong JW, Giudice LC, Fazleabas AT

Defining future directions for endometriosis research: workshop report from the 2011 World Congress of Endometriosis In Montpellier, France.

Reproductive sciences (Thousand Oaks, Calif.)

Rogers PA, D'Hooghe TM, Fazleabas A, Giudice LC, Montgomery GW, Petraglia F, Taylor RN

Perfluorochemicals and endometriosis: the ENDO study.

Epidemiology (Cambridge, Mass.)

Louis GM, Peterson CM, Chen Z, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Fujimoto VY, Varner MW, Giudice LC, Kennedy A, Sun L, Wu Q, Kannan K

Role of decreased androgens in the ovarian response to stimulation in older women.

Fertility and sterility

Meldrum DR, Chang RJ, Giudice LC, Balasch J, Barbieri RL

Ectopic uterine tissue as a chronic pain generator.

Neuroscience

Alvarez P, Chen X, Hendrich J, Irwin JC, Green PG, Giudice LC, Levine JD

Pathogenesis and pathophysiology of endometriosis.

Fertility and sterility

Burney RO, Giudice LC

Persistent lipophilic environmental chemicals and endometriosis: the ENDO Study.

Environmental health perspectives

Buck Louis GM, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice LC, Trumble A, Parsons PJ, Kannan K

Molecular probe technology detects bacteria without culture.

BMC microbiology

Hyman RW, St Onge RP, Kim H, Tamaresis JS, Miranda M, Aparicio AM, Fukushima M, Pourmand N, Giudice LC, Davis RW

Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures.

American journal of obstetrics and gynecology

Sutton P, Woodruff TJ, Perron J, Stotland N, Conry JA, Miller MD, Giudice LC

Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype.

Biology of reproduction

Spitzer TL, Rojas A, Zelenko Z, Aghajanova L, Erikson DW, Barragan F, Meyer M, Tamaresis JS, Hamilton AE, Irwin JC, Giudice LC

Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis.

The Journal of clinical endocrinology and metabolism

Pabona JM, Simmen FA, Nikiforov MA, Zhuang D, Shankar K, Velarde MC, Zelenko Z, Giudice LC, Simmen RC

The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer.

Journal of assisted reproduction and genetics

Hyman RW, Herndon CN, Jiang H, Palm C, Fukushima M, Bernstein D, Vo KC, Zelenko Z, Davis RW, Giudice LC

High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples.

Human reproduction (Oxford, England)

Leach RE, Jessmon P, Coutifaris C, Kruger M, Myers ER, Ali-Fehmi R, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Leppert PC, Giudice L, Diamond MP, Armant DR

SGK1: a fine balancing act for human pregnancy.

Nature medicine

Fisher SJ, Giudice LC

Incidence of endometriosis by study population and diagnostic method: the ENDO study.

Fertility and sterility

Buck Louis GM, Hediger ML, Peterson CM, Croughan M, Sundaram R, Stanford J, Chen Z, Fujimoto VY, Varner MW, Trumble A, Giudice LC

Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.

The Journal of clinical endocrinology and metabolism

Savaris RF, Groll JM, Young SL, DeMayo FJ, Jeong JW, Hamilton AE, Giudice LC, Lessey BA

Transcriptomic signature of trophoblast differentiation in a human embryonic stem cell model.

Biology of reproduction

Marchand M, Horcajadas JA, Esteban FJ, McElroy SL, Fisher SJ, Giudice LC

Effect of bisphenol A on human endometrial stromal fibroblasts in vitro.

Reproductive biomedicine online

Aghajanova L, Giudice LC

Reproductive environmental health.

Current opinion in obstetrics & gynecology

Sutton P, Giudice LC, Woodruff TJ

Molecular evidence for differences in endometrium in severe versus mild endometriosis.

Reproductive sciences (Thousand Oaks, Calif.)

Aghajanova L, Giudice LC

Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.

Biology of reproduction

Aghajanova L, Tatsumi K, Horcajadas JA, Zamah AM, Esteban FJ, Herndon CN, Conti M, Giudice LC

Clinical practice. Endometriosis.

The New England journal of medicine

Giudice LC

Racial and ethnic disparities in benign gynecologic conditions and associated surgeries.

American journal of obstetrics and gynecology

Jacoby VL, Fujimoto VY, Giudice LC, Kuppermann M, Washington AE

Research agenda for environmental reproductive health in the 21st century.

Journal of epidemiology and community health

Woodruff TJ, Schwartz J, Giudice LC

Racial and ethnic disparities in reproductive endocrinology and infertility.

American journal of obstetrics and gynecology

Huddleston HG, Cedars MI, Sohn SH, Giudice LC, Fujimoto VY

Research ethics. NIH guidelines for stem cell research and gamete donors.

Science (New York, N.Y.)

Lo B, Parham L, Cedars M, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Rao R, Roberts C, Wagner R

The bone marrow-derived human mesenchymal stem cell: potential progenitor of the endometrial stromal fibroblast.

Biology of reproduction

Aghajanova L, Horcajadas JA, Esteban FJ, Giudice LC

Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility.

Biology of reproduction

Nyegaard M, Overgaard MT, Su YQ, Hamilton AE, Kwintkiewicz J, Hsieh M, Nayak NR, Conti M, Conover CA, Giudice LC

Altered gene expression profiling in endometrium: evidence for progesterone resistance.

Seminars in reproductive medicine

Aghajanova L, Velarde MC, Giudice LC

Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.

Cell stem cell

Lo B, Parham L, Alvarez-Buylla A, Cedars M, Conklin B, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Wagner R

Gene expression during successful implantation in a natural cycle.

Fertility and sterility

Van Vaerenbergh I, McIntire R, Van Lommel L, Devroey P, Giudice L, Bourgain C

MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis.

Molecular human reproduction

Burney RO, Hamilton AE, Aghajanova L, Vo KC, Nezhat CN, Lessey BA, Giudice LC

Body mass index and intercourse compliance.

Fertility and sterility

Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC

Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial.

Fertility and sterility

Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC

Predictors of pregnancy in women with polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism

Rausch ME, Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER, Coutifaris C

Endocrine-disrupting chemicals: an Endocrine Society scientific statement.

Endocrine reviews

Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, Zoeller RT, Gore AC

Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.

Proceedings of the National Academy of Sciences of the United States of America

Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ

Editorial: Update on stem cell research.

Endocrine reviews

Robertson RP, Giudice LC

Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns.

Cell stem cell

Lo B, Parham L, Broom C, Cedars M, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Oberman M, Roberts C, Wagner R

Priorities for endometriosis research: recommendations from an international consensus workshop.

Reproductive sciences (Thousand Oaks, Calif.)

Rogers PA, D'Hooghe TM, Fazleabas A, Gargett CE, Giudice LC, Montgomery GW, Rombauts L, Salamonsen LA, Zondervan KT

Genomics analysis: endometrium.

Methods in molecular biology (Clifton, N.J.)

Savaris RF, Giudice LC

From stem cells to germ cells and back again.

Nature medicine

Conti M, Giudice L

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.

Fertility and sterility

Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ

Environmental exposures and adverse pregnancy outcomes: a review of the science.

Reproductive sciences (Thousand Oaks, Calif.)

Stillerman KP, Mattison DR, Giudice LC, Woodruff TJ

Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications.

The Journal of clinical endocrinology and metabolism

Horcajadas JA, Mínguez P, Dopazo J, Esteban FJ, Domínguez F, Giudice LC, Pellicer A, Simón C

VEGF blockade inhibits angiogenesis and reepithelialization of endometrium.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Fan X, Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice LC, Nayak NR

Endometrial gene expression in early pregnancy: lessons from human ectopic pregnancy.

Reproductive sciences (Thousand Oaks, Calif.)

Savaris RF, Hamilton AE, Lessey BA, Giudice LC

Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism

Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC

Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer.

Reproductive biomedicine online

McElroy SL, Kee K, Tran N, Menses J, Giudice LC, Reijo Pera RA

The impact of ovarian stimulation with recombinant FSH in combination with GnRH antagonist on the endometrial transcriptome in the window of implantation.

Reproductive sciences (Thousand Oaks, Calif.)

Macklon NS, van der Gaast MH, Hamilton A, Fauser BC, Giudice LC

Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone.

The Journal of endocrinology

Dosiou C, Hamilton AE, Pang Y, Overgaard MT, Tulac S, Dong J, Thomas P, Giudice LC

Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial.

Fertility and sterility

McGovern PG, Carson SA, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC

Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene.

The Journal of clinical endocrinology and metabolism

Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Ewens KG, Spielman RS, Leppert PC, Myers ER

The influence of hydrosalpinx on markers of endometrial receptivity.

Seminars in reproductive medicine

Savaris RF, Giudice LC

Uterine receptivity to human embryonic implantation: histology, biomarkers, and transcriptomics.

Seminars in cell & developmental biology

Aghajanova L, Hamilton AE, Giudice LC

Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis.

Endocrinology

Burney RO, Talbi S, Hamilton AE, Vo KC, Nyegaard M, Nezhat CR, Lessey BA, Giudice LC

Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.

The New England journal of medicine

Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER

Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome.

Fertility and sterility

McGovern PG, Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC

Decidual stromal cell response to paracrine signals from the trophoblast: amplification of immune and angiogenic modulators.

Biology of reproduction

Hess AP, Hamilton AE, Talbi S, Dosiou C, Nyegaard M, Nayak N, Genbecev-Krtolica O, Mavrogianis P, Ferrer K, Kruessel J, Fazleabas AT, Fisher SJ, Giudice LC

Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.

The Journal of clinical investigation

Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ

Infertility and the environment: the medical context.

Seminars in reproductive medicine

Giudice LC

A twenty-first century research agenda for polycystic ovary syndrome.

Best practice & research. Clinical endocrinology & metabolism

Legro RS, Azziz R, Giudice L

Endometrium in PCOS: Implantation and predisposition to endocrine CA.

Best practice & research. Clinical endocrinology & metabolism

Giudice LC

Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells.

The Journal of clinical endocrinology and metabolism

Tulac S, Overgaard MT, Hamilton AE, Jumbe NL, Suchanek E, Giudice LC

The science behind 25 years of ovarian stimulation for in vitro fertilization.

Endocrine reviews

Macklon NS, Stouffer RL, Giudice LC, Fauser BC

Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth.

Molecular human reproduction

Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice LC, Brenner RM

Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation.

Reproduction, fertility, and development

Hess AP, Hirchenhain J, Schanz A, Talbi S, Hamilton AE, Giudice LC, Krüssel JS

Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.

Lymphatic research and biology

Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ

Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles.

Fertility and sterility

Littman E, Giudice L, Lathi R, Berker B, Milki A, Nezhat C

The dilemma of endometriosis: is consensus possible with an enigma?

Fertility and sterility

Nezhat C, Littman ED, Lathi RB, Berker B, Westphal LM, Giudice LC, Milki AA

Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women.

Endocrinology

Talbi S, Hamilton AE, Vo KC, Tulac S, Overgaard MT, Dosiou C, Le Shay N, Nezhat CN, Kempson R, Lessey BA, Nayak NR, Giudice LC

IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch.

Molecular human reproduction

Li T, Vu TH, Ulaner GA, Littman E, Ling JQ, Chen HL, Hu JF, Behr B, Giudice L, Hoffman AR

Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome.

Human reproduction (Oxford, England)

Cataldo NA, Abbasi F, McLaughlin TL, Basina M, Fechner PY, Giudice LC, Reaven GM

Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.

Endocrinology

Tang M, Mikhailik A, Pauli I, Giudice LC, Fazelabas AT, Tulac S, Carson DD, Kaufman DG, Barbier C, Creemers JW, Tabibzadeh S

Microbes on the human vaginal epithelium.

Proceedings of the National Academy of Sciences of the United States of America

Hyman RW, Fukushima M, Diamond L, Kumm J, Giudice LC, Davis RW

Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements.

The Journal of biological chemistry

Glerup S, Boldt HB, Overgaard MT, Sottrup-Jensen L, Giudice LC, Oxvig C

Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic Acid in the human and rhesus macaque endometrium.

The Journal of clinical endocrinology and metabolism

Germeyer A, Hamilton AE, Laughlin LS, Lasley BL, Brenner RM, Giudice LC, Nayak NR

Dose-dependent insulin regulation of insulin-like growth factor binding protein-1 in human endometrial stromal cells is mediated by distinct signaling pathways.

The Journal of clinical endocrinology and metabolism

Lathi RB, Hess AP, Tulac S, Nayak NR, Conti M, Giudice LC

Absence of secretory endometrium after false-positive home urine luteinizing hormone testing.

Fertility and sterility

McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Giudice LC, Leppert PC, Diamond MP

Endometriosis.

Lancet (London, England)

Giudice LC, Kao LC

The immune environment in human endometrium during the window of implantation.

American journal of reproductive immunology (New York, N.Y. : 1989)

Lobo SC, Huang ST, Germeyer A, Dosiou C, Vo KC, Tulac S, Nayak NR, Giudice LC

Developmental response to hypoxia.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Huang ST, Vo KC, Lyell DJ, Faessen GH, Tulac S, Tibshirani R, Giaccia AJ, Giudice LC

The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.

The Journal of biological chemistry

Boldt HB, Kjaer-Sorensen K, Overgaard MT, Weyer K, Poulsen CB, Sottrup-Jensen L, Conover CA, Giudice LC, Oxvig C

Interferon-related and other immune genes are downregulated in peripheral blood leukocytes in the luteal phase of the menstrual cycle.

The Journal of clinical endocrinology and metabolism

Dosiou C, Lathi RB, Tulac S, Huang ST, Giudice LC

Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module.

European journal of biochemistry

Weyer K, Overgaard MT, Laursen LS, Nielsen CG, Schmitz A, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C

Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase.

FEBS letters

Overgaard MT, Glerup S, Boldt HB, Rodacker V, Olsen IM, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C

Microarray expression profiling reveals candidate genes for human uterine receptivity.

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Giudice LC

Comparison of the sex ratio with blastocyst transfer and cleavage stage transfer.

Journal of assisted reproduction and genetics

Milki AA, Jun SH, Hinckley MD, Westphal LW, Giudice LC, Behr B

Identification, characterization, and regulation of the canonical Wnt signaling pathway in human endometrium.

The Journal of clinical endocrinology and metabolism

Tulac S, Nayak NR, Kao LC, Van Waes M, Huang J, Lobo S, Germeyer A, Lessey BA, Taylor RN, Suchanek E, Giudice LC

Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility.

Endocrinology

Kao LC, Germeyer A, Tulac S, Lobo S, Yang JP, Taylor RN, Osteen K, Lessey BA, Giudice LC

Prenatal screening, epidemiology, diagnosis, and management of preeclampsia.

Clinics in laboratory medicine

Lyell DJ, Lambert-Messerlian GM, Giudice LC

Elucidating endometrial function in the post-genomic era.

Human reproduction update

Giudice LC

Genomics' role in understanding the pathogenesis of endometriosis.

Seminars in reproductive medicine

Giudice LC

Incidence of monozygotic twinning with blastocyst transfer compared to cleavage-stage transfer.

Fertility and sterility

Milki AA, Jun SH, Hinckley MD, Behr B, Giudice LC, Westphal LM

Regulation of insulin-like growth factor-I and insulin-like growth factor binding protein-1 concentrations in preterm fetuses.

American journal of obstetrics and gynecology

Verhaeghe J, Van Herck E, Billen J, Moerman P, Van Assche FA, Giudice LC

Maternal-fetal conflict--lessons from a transgene.

The Journal of clinical investigation

Giudice LC

Global gene profiling in human endometrium during the window of implantation.

Endocrinology

Kao LC, Tulac S, Lobo S, Imani B, Yang JP, Germeyer A, Osteen K, Taylor RN, Lessey BA, Giudice LC

Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation.

The Journal of clinical endocrinology and metabolism

Giudice LC, Conover CA, Bale L, Faessen GH, Ilg K, Sun I, Imani B, Suen LF, Irwin JC, Christiansen M, Overgaard MT, Oxvig C

A longitudinal analysis of maternal serum insulin-like growth factor I (IGF-I) and total and nonphosphorylated IGF-binding protein-1 in human pregnancies complicated by intrauterine growth restriction.

The Journal of clinical endocrinology and metabolism

Bhatia S, Faessen GH, Carland G, Balise RL, Gargosky SE, Druzin M, El-Sayed Y, Wilson DM, Giudice LC

Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity.

European journal of biochemistry

Søe R, Overgaard MT, Thomsen AR, Laursen LS, Olsen IM, Sottrup-Jensen L, Haaning J, Giudice LC, Conover CA, Oxvig C

Insulin-like growth factor family in Graafian follicle development and function.

Journal of the Society for Gynecologic Investigation

Giudice LC

Multiple pregnancies: what action should we take?

Fertility and sterility

Paulson RJ, Ory SJ, Giudice LC, Schlaff WD, Santoro NF, Coddington CC

Regulation of insulin-like growth factor-binding protein 1 by hypoxia and 3',5'-cyclic adenosine monophosphate is additive in HepG2 cells.

The Journal of clinical endocrinology and metabolism

Sugawara J, Tazuke SI, Suen LF, Powell DR, Kaper F, Giaccia AJ, Giudice LC

Regulation of insulin-like growth factor-binding protein-1 by nitric oxide under hypoxic conditions.

The Journal of clinical endocrinology and metabolism

Sugawara J, Suh DS, Faessen GH, Suen LF, Shibata T, Kaper F, Giaccia AJ, Giudice LC

Free androgen index and leptin are the most prominent endocrine predictors of ovarian response during clomiphene citrate induction of ovulation in normogonadotropic oligoamenorrheic infertility.

The Journal of clinical endocrinology and metabolism

Imani B, Eijkemans MJ, de Jong FH, Payne NN, Bouchard P, Giudice LC, Fauser BC

Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A.

The Journal of clinical endocrinology and metabolism

Conover CA, Oxvig C, Overgaard MT, Christiansen M, Giudice LC

Potential biochemical markers of uterine receptivity.

Human reproduction (Oxford, England)

Giudice LC

Role of the IGF system in trophoblast invasion and pre-eclampsia.

Human reproduction (Oxford, England)

Irwin JC, Suen LF, Martina NA, Mark SP, Giudice LC

Elevated serum levels of free insulin-like growth factor I in polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism

Thierry van Dessel HJ, Lee PD, Faessen G, Fauser BC, Giudice LC

The insulin-related ovarian regulatory system in health and disease.

Endocrine reviews

Poretsky L, Cataldo NA, Rosenwaks Z, Giudice LC

Growth factor action on ovarian function in polycystic ovary syndrome.

Endocrinology and metabolism clinics of North America

Giudice LC

Dysfunctional uterine bleeding.

The Western journal of medicine

Chen BH, Giudice LC

Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia.

Proceedings of the National Academy of Sciences of the United States of America

Tazuke SI, Mazure NM, Sugawara J, Carland G, Faessen GH, Suen LF, Irwin JC, Powell DR, Giaccia AJ, Giudice LC

Medical management of interstitial ectopic pregnancy: a case report and literature review.

Human reproduction (Oxford, England)

Fisch JD, Ortiz BH, Tazuke SI, Chitkara U, Giudice LC

Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.

The Journal of clinical endocrinology and metabolism

Azhar S, Tsai L, Medicherla S, Chandrasekher Y, Giudice L, Reaven E

Status of current research on endometriosis.

The Journal of reproductive medicine

Giudice LC, Tazuke SI, Swiersz L

Insulin-like growth factor binding protein-1 binds to placental cytotrophoblast alpha5beta1 integrin and inhibits cytotrophoblast invasion into decidualized endometrial stromal cultures.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society

Irwin JC, Giudice LC

Insulin-like growth factor binding protein-1: recent findings and new directions.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

Lee PD, Giudice LC, Conover CA, Powell DR

Programmed cell death in human ovary is a function of follicle and corpus luteum status.

The Journal of clinical endocrinology and metabolism

Yuan W, Giudice LC

Laparoscopic management of a noncommunicating uterine horn in a patient with an acute abdomen.

Surgical laparoscopy & endoscopy

Amara DP, Nezhat F, Giudice L, Nezhat C

Role of growth hormone in ovarian physiology and onset of puberty.

Journal of the Society for Gynecologic Investigation

Sharara FI, Giudice LC

Growth factors and polycystic ovarian syndrome.

Seminars in reproductive endocrinology

Giudice LC, Morales AJ, Yen SS

Growth factors in normal ovarian follicle development.

Seminars in reproductive endocrinology

Giudice LC, Cataldo NA, van Dessel HJ, Yap OW, Chandrasekher YA

Insulin-like growth factor binding proteins in peritoneal fluid of women with minimal and mild endometriosis.

Human reproduction (Oxford, England)

Taskin O, Giudice L, Mangal R, Dunn RC, Dsupin BA, Poindexter AN, Wiehle RD

Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age.

The Journal of clinical endocrinology and metabolism

Klein NA, Battaglia DE, Miller PB, Branigan EF, Giudice LC, Soules MR

Polycystic ovary syndrome.

Human reproduction (Oxford, England)

Homburg R, Giudice LC, Chang RJ

Serum and follicular fluid levels of insulin-like growth factor I (IGF-I), IGF-II, and IGF-binding protein-1 and -3 during the normal menstrual cycle.

The Journal of clinical endocrinology and metabolism

Thierry van Dessel HJ, Chandrasekher Y, Yap OW, Lee PD, Hintz RL, Faessen GH, Braat DD, Fauser BC, Giudice LC

Insulin receptor mediates inhibitory effect of insulin, but not of insulin-like growth factor (IGF)-I, on IGF binding protein 1 (IGFBP-1) production in human granulosa cells.

The Journal of clinical endocrinology and metabolism

Poretsky L, Chandrasekher YA, Bai C, Liu HC, Rosenwaks Z, Giudice L

Estrogen- but not androgen-dominant human ovarian follicular fluid contains an insulin-like growth factor binding protein-4 protease.

The Journal of clinical endocrinology and metabolism

Chandrasekher YA, Van Dessel HJ, Fauser BC, Giudice LC

IGF binding protein-3 protease regulation: how sweet it is!

The Journal of clinical endocrinology and metabolism

Giudice LC

Radiation-induced premature menopause: a misconception.

International journal of radiation oncology, biology, physics

Madsen BL, Giudice L, Donaldson SS

Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth.

The Journal of clinical endocrinology and metabolism

Giudice LC, de Zegher F, Gargosky SE, Dsupin BA, de las Fuentes L, Crystal RA, Hintz RL, Rosenfeld RG

Follicular fluid insulin-like growth factor-I and insulin-like growth factor-II concentrations vary as a function of day 3 serum follicle stimulating hormone.

Human reproduction (Oxford, England)

Seifer DB, Giudice LC, Dsupin BA, Haning RV, Frishman GN, Burger HG

Ovulatory function in epilepsy.

Epilepsia

Cummings LN, Giudice L, Morrell MJ

Growth factors in reproduction.

Trends in endocrinology and metabolism: TEM

Giudice LC, Saleh W

Circulating and ovarian IGF binding proteins: potential roles in normo-ovulatory cycles and in polycystic ovarian syndrome.

Progress in growth factor research

Giudice LC, van Dessel HJ, Cataldo NA, Chandrasekher YA, Yap OW, Fauser BC

Insulin-like growth factor system gene expression in human endometrium during the menstrual cycle.

The Journal of clinical endocrinology and metabolism

Zhou J, Dsupin BA, Giudice LC, Bondy CA

The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis.

The Journal of clinical endocrinology and metabolism

Giudice LC, Dsupin BA, Gargosky SE, Rosenfeld RG, Irwin JC

Growth factors and decidualization in vitro.

Annals of the New York Academy of Sciences

Irwin JC, de las Fuentes L, Giudice LC

Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones.

The Journal of clinical investigation

Rodgers WH, Matrisian LM, Giudice LC, Dsupin B, Cannon P, Svitek C, Gorstein F, Osteen KG

Adnexal torsion: color Doppler diagnosis and laparoscopic treatment.

Fertility and sterility

Gordon JD, Hopkins KL, Jeffrey RB, Giudice LC

Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata.

Human reproduction (Oxford, England)

Giudice LC, Irwin JC, Dsupin BA, Pannier EM, Jin IH, Vu TH, Hoffman AR

Ethics of fetal tissue transplantation.

The Western journal of medicine

Sanders LM, Giudice L, Raffin TA

The potential roles of intraovarian peptides in normal and abnormal mechanisms of reproductive physiology.

Current opinion in obstetrics & gynecology

Giudice LC, Chandrasekher YA, Cataldo NA

Differential expression of messenger ribonucleic acids encoding insulin-like growth factors and their receptors in human uterine endometrium and decidua.

The Journal of clinical endocrinology and metabolism

Giudice LC, Dsupin BA, Jin IH, Vu TH, Hoffman AR

Insulin-like growth factor binding proteins in sera of pregnant nonhuman primates.

Endocrinology

Giudice LC, Dsupin BA, De las Fuentes L, Gargosky SE, Rosenfeld RG, Zelinski-Wooten MB, Stouffer RL, Fazleabas AT

Proteolysis of IGFBP-3 may be a common regulatory mechanism of IGF action in vivo.

Growth regulation

Lamson G, Giudice LC, Cohen P, Liu F, Gargosky S, Müller HL, Oh Y, Wilson KF, Hintz RL, Rosenfeld RG

Comparison of functional response of rat, macaque, and human ovarian cells in hormonally defined medium.

Biology of reproduction

Woodruff TK, Battaglia J, Bowdidge A, Molskness TA, Stouffer RL, Cataldo NA, Giudice LC, Orly J, Mather JP

Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle.

American journal of obstetrics and gynecology

Rodgers WH, Osteen KG, Matrisian LM, Navre M, Giudice LC, Gorstein F

Regulation of insulin-like growth factor binding protein production by human luteinizing granulosa cells cultured in defined medium.

The Journal of clinical endocrinology and metabolism

Cataldo NA, Woodruff TK, Giudice LC

Local anesthesia with conscious sedation for laparoscopic intrafallopian transfer.

Fertility and sterility

Milki AA, Hardy RI, el Danasouri I, Giudice LC, Lamb EJ

Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma.

The Journal of clinical endocrinology and metabolism

Cohen P, Graves HC, Peehl DM, Kamarei M, Giudice LC, Rosenfeld RG

Follicular fluid insulin-like growth factor binding protein profiles in polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism

Cataldo NA, Giudice LC

Identification of insulin-like growth factor binding proteins in human oviduct.

Fertility and sterility

Giudice LC, Dsupin BA, Irwin JC, Eckert RL

Maternal insulin-like growth factor-binding protein messenger ribonucleic acid during rat pregnancy.

Endocrinology

Donovan SM, Giudice LC, Murphy LJ, Hintz RL, Rosenfeld RG

A simple assay for proteolysis of IGFBP-3.

The Journal of clinical endocrinology and metabolism

Lamson G, Giudice LC, Rosenfeld RG

Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis.

The Journal of clinical endocrinology and metabolism

Giudice LC, Milkowski DA, Lamson G, Rosenfeld RG, Irwin JC

Clinical aspects of insulin-like growth factor binding proteins.

Acta endocrinologica

Cohen P, Fielder PJ, Hasegawa Y, Frisch H, Giudice LC, Rosenfeld RG

Insulin-like growth factor binding proteins: structural and molecular relationships.

Growth factors (Chur, Switzerland)

Lamson G, Giudice LC, Rosenfeld RG

Insulin-like growth factor-II (IGF-II) and IGF binding proteins in human endometrium.

Annals of the New York Academy of Sciences

Giudice LC, Lamson G, Rosenfeld RG, Irwin JC

Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) and IGFBP-2 in human follicular fluid.

The Journal of clinical endocrinology and metabolism

Giudice LC, Farrell EM, Pham H, Rosenfeld RG

Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma.

The Journal of clinical endocrinology and metabolism

Rosenfeld RG, Pham H, Oh Y, Lamson G, Giudice LC

Insulinlike growth factor-binding proteins.

Recent progress in hormone research

Rosenfeld RG, Lamson G, Pham H, Oh Y, Conover C, De Leon DD, Donovan SM, Ocrant I, Giudice L

Cryopreservation of embryos and ova.

Fertility and sterility

Friedler S, Giudice LC, Lamb EJ

Angiographic arterial embolization to control hemorrhage in abdominal pregnancy: a case report.

Obstetrics and gynecology

Kivikoski AI, Martin C, Weyman P, Picus D, Giudice L

Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman.

Fertility and sterility

Sauer MV, Macaso TM, Ishida EH, Giudice L, Marshall JR, Buster JE

Clinical results of Stanford University's in vitro fertilization and embryo transfer program.

Journal of in vitro fertilization and embryo transfer : IVF

Lamb EJ, Polansky F, Milki A, Giudice LC, Friedler S, Wu T, Shen E, Turner K, Ho L

Serum levels of CA-125 in patients with endometriosis: a preliminary report.

Fertility and sterility

Giudice LC, Jacobs A, Pineda J, Bell CE, Lippmann L

The function of the common subunit of glycoprotein hormones.

Biochemical Society transactions

Pierce JG, Bloomfield GA, Giudice LC

Structure and structure-function relationships in glycoprotein hormones.

Ciba Foundation symposium

Pierce JG, Faith MR, Giudice LC, Reeve JR