Stephen Hauser, MD

Professor
Neurology
[email protected]
+1 415 476-9211

Stephen L. Hauser, M.D. is the Robert A. Fishman Distinguished Professor of Neurology at the University of California, San Francisco (UCSF). He is Director of the UCSF Weill Institute for Neurosciences, an umbrella organization that links the clinical and basic neurosciences at UCSF to accelerate research against neurologic diseases. A neuroimmunologist, Dr. Hauser’s research has advanced our understanding of the genetic basis, immune mechanisms, and treatment of multiple sclerosis (MS). His work led to the development of B cell therapies for MS patients, representing a powerful new approach for treating all forms of the disease and the first therapy of proven value for progressive MS.

Dr. Hauser is a member of the National Academy of Medicine and a fellow of the American Academy of Arts and Sciences and the American Academy of Physicians. He is an editor of the medical textbook Harrison’s Principles of Internal Medicine. Previously chairman of the Department of Neurology at UCSF for 25 years, he has also served as President of the American Neurological Association, President of the Medical Staff at UCSF, Chair of the Research Advisory Committee for the U.S. Department of Veterans Affairs, and editor-in-chief of Annals of Neurology. He also served the Obama administration as a member of the Presidential Commission for the Study of Bioethical Issues charged with advising the President on issues that may emerge from advances in biomedicine and related areas of science and technology.

Dr. Hauser has received numerous awards and honors for his work, including the Jacob Javits Neuroscience Investigator Award, the John Dystel Prize for Multiple Sclerosis Research (2008), the Charcot Award (2013), the Taubman Prize for Excellence in Translational Medical Research (2017), and the Scientific Breakthrough Award from the American Brain Foundation (2022).

Dr. Hauser is a graduate of the Massachusetts Institute of Technology (Phi Beta Kappa) and Harvard Medical School (Magna Cum Laude). He trained in internal medicine at the New York Hospital–Cornell Medical Center, in neurology at the Massachusetts General Hospital, and in immunology at Harvard Medical School and the Institute Pasteur in Paris, France. He was a faculty member at Harvard Medical School before moving to UCSF.

Publications: 

Programming tissue-sensing T cells that deliver therapies to the brain.

Science (New York, N.Y.)

Simic MS, Watchmaker PB, Gupta S, Wang Y, Sagan SA, Duecker J, Shepherd C, Diebold D, Pineo-Cavanaugh P, Haegelin J, Zhu R, Ng B, Yu W, Tonai Y, Cardarelli L, Reddy NR, Sidhu SS, Troyanskaya O, Hauser SL, Wilson MR, Zamvil SS, Okada H, Lim WA

Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials.

Therapeutic advances in neurological disorders

Derfuss T, Bermel R, Lin CJ, Hauser SL, Kappos L, Vollmer T, Comi G, Giovannoni G, Hartung HP, Weber MS, Wang J, Jessop N, Chognot C, Craveiro L, Bar-Or A

Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis.

bioRxiv : the preprint server for biology

Mittl K, Hayashi F, Dandekar R, Schubert RD, Gerdts J, Oshiro L, Loudermilk R, Greenfield A, Augusto DG, Ramesh A, Tran E, Koshal K, Kizer K, Dreux J, Cagalingan A, Schustek F, Flood L, Moore T, Kirkemo LL, Cooper T, Harms M, Gomez R, University of California, San Francisco MS-EPIC Team, Sibener L, Cree BAC, Hauser SL, Hollenbach JA, Gee M, Wilson MR, Zamvil SS, Sabatino JJ

Author Correction: Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

Nature medicine

Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJM, Green A, Hauser SL, Chan JR

Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency.

Science translational medicine

Pluvinage JV, Ngo T, Fouassier C, McDonagh M, Holmes BB, Bartley CM, Kondapavulur S, Hurabielle C, Bodansky A, Pai V, Hinman S, Aslanpour A, Alvarenga BD, Zorn KC, Zamecnik C, McCann A, Asencor AI, Huynh T, Browne W, Tubati A, Haney MS, Douglas VC, Louine M, Cree BAC, Hauser SL, Seeley W, Baranzini SE, Wells JA, Spudich S, Farhadian S, Ramachandran PS, Gillum L, Hales CM, Zikherman J, Anderson MS, Yazdany J, Smith B, Nath A, Suh G, Flanagan EP, Green AJ, Green R, Gelfand JM, DeRisi JL, Pleasure SJ, Wilson MR

Inflammatory and neurodegenerative serum protein biomarkers increase sensitivity to detect clinical and radiographic disease activity in multiple sclerosis.

Nature communications

Chitnis T, Qureshi F, Gehman VM, Becich M, Bove R, Cree BAC, Gomez R, Hauser SL, Henry RG, Katrib A, Lokhande H, Paul A, Caillier SJ, Santaniello A, Sattarnezhad N, Saxena S, Weiner H, Yano H, Baranzini SE

An autoantibody signature predictive for multiple sclerosis.

Nature medicine

Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Kizer K, Augusto DG, Tubati A, Gomez R, Fouassier C, Gerungan C, Caspar CM, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Sabatino JJ, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BAC, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR

Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis.

Cell reports. Medicine

Cordano C, Werneburg S, Abdelhak A, Bennett DJ, Beaudry-Richard A, Duncan GJ, Oertel FC, Boscardin WJ, Yiu HH, Jabassini N, Merritt L, Nocera S, Sin JH, Samana IP, Condor Montes SY, Ananth K, Bischof A, UCSF MS EPIC Team, Nourbakhsh B, Hauser SL, Cree BAC, Emery B, Schafer DP, Chan JR, Green AJ

Silencing Immune Dialogue in Multiple Sclerosis.

The New England journal of medicine

Hauser SL

High-resolution DNA methylation screening of the major histocompatibility complex in multiple sclerosis.

Frontiers in neurology

Ma Q, Augusto DG, Montero-Martin G, Caillier SJ, Osoegawa K, Cree BAC, Hauser SL, Didonna A, Hollenbach JA, Norman PJ, Fernandez-Vina M, Oksenberg JR

Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis.

JAMA neurology

Abdelhak A, Benkert P, Schaedelin S, Boscardin WJ, Cordano C, Oechtering J, Ananth K, Granziera C, Melie-Garcia L, Montes SC, Beaudry-Richard A, Achtnichts L, Oertel FC, Lalive PH, Leppert D, Müller S, Henry RG, Pot C, Matthias A, Salmen A, Oksenberg JR, Disanto G, Zecca C, D'Souza M, Du Pasquier R, Bridel C, Gobbi C, Kappos L, Hauser SL, Cree BAC, Kuhle J, Green AJ, UCSF, MS EPIC, and the SMSC Study Teams

Patient-reported outcome parameters and disability worsening in progressive multiple sclerosis.

Multiple sclerosis and related disorders

Abdelhak A, Antweiler K, Kowarik MC, Senel M, Havla J, Zettl UK, Kleiter I, Hoshi MM, Skripuletz T, Haarmann A, Stahmann A, Huss A, Gingele S, Krumbholz M, Selge C, Friede T, Ludolph AC, Overell J, Koendgen H, Clinch S, Wang Q, Ziemann U, Hauser SL, Kümpfel T, Green AJ, Tumani H

Ocrelizumab exposure in relapsing-remitting multiple sclerosis: 10-year analysis of the phase 2 randomized clinical trial and its extension.

Journal of neurology

Kappos L, Traboulsee A, Li DKB, Bar-Or A, Barkhof F, Montalban X, Leppert D, Baldinotti A, Schneble HM, Koendgen H, Sauter A, Wang Q, Hauser SL

A metagenomics method for the quantitative detection of bacterial pathogens causing hospital-associated and ventilator-associated pneumonia.

Microbiology spectrum

Hauser S, Lazarevic V, Tournoud M, Ruppé E, Santiago Allexant E, Guigon G, Schicklin S, Lanet V, Girard M, Mirande C, Gervasi G, Schrenzel J

Efficacy and safety of four-year ofatumumab treatment in relapsing multiple sclerosis: The ALITHIOS open-label extension.

Multiple sclerosis (Houndmills, Basingstoke, England)

Hauser SL, Zielman R, Das Gupta A, Xi J, Stoneman D, Karlsson G, Robertson D, Cohen JA, Kappos L

Progressive multifocal leukoencephalopathy in a patient with relapsing multiple sclerosis treated with ocrelizumab: A case report.

European journal of neurology

Puig-Casadevall M, Álvarez-Bravo G, Varela AQ, Robles-Cedeño R, Sànchez Cirera L, Miguela A, Laguillo G, Montalban X, Hauser SL, Ramió-Torrentà L

The Development of Ofatumumab, a Fully Human Anti-CD20 Monoclonal Antibody for Practical Use in Relapsing Multiple Sclerosis Treatment.

Neurology and therapy

Hauser SL, Kappos L, Bar-Or A, Wiendl H, Paling D, Williams M, Gold R, Chan A, Milo R, Das Gupta A, Karlsson G, Sullivan R, Graham G, Merschhemke M, Häring DA, Vermersch P

Inflammatory and neurodegenerative serum protein biomarkers increase sensitivity to detect disease activity in multiple sclerosis.

medRxiv : the preprint server for health sciences

Chitnis T, Qureshi F, Gehman VM, Becich M, Bove R, Cree BAC, Gomez R, Hauser SL, Henry RG, Katrib A, Lokhande H, Paul A, Caillier SJ, Santaniello A, Sattarnezhad N, Saxena S, Weiner H, Yano H, Baranzini SE

Blood neurofilament light levels predict non-relapsing progression following anti-CD20 therapy in relapsing and primary progressive multiple sclerosis: findings from the ocrelizumab randomised, double-blind phase 3 clinical trials.

EBioMedicine

Bar-Or A, Thanei GA, Harp C, Bernasconi C, Bonati U, Cross AH, Fischer S, Gaetano L, Hauser SL, Hendricks R, Kappos L, Kuhle J, Leppert D, Model F, Sauter A, Koendgen H, Jia X, Herman AE

A Predictive Autoantibody Signature in Multiple Sclerosis.

medRxiv : the preprint server for health sciences

Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Tubati A, Gomez R, Fouassier C, Gerungan C, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BA, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR

Integration of epigenetic and genetic profiles identifies multiple sclerosis disease-critical cell types and genes.

Communications biology

Ma Q, Shams H, Didonna A, Baranzini SE, Cree BAC, Hauser SL, Henry RG, Oksenberg JR

Association of Higher Ocrelizumab Exposure With Reduced Disability Progression in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Hauser SL, Bar-Or A, Weber MS, Kletzl H, Günther A, Manfrini M, Model F, Mercier F, Petry C, Wing Q, Koendgen H, Smith T, Kappos L

Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans.

Brain : a journal of neurology

Shams H, Shao X, Santaniello A, Kirkish G, Harroud A, Ma Q, Isobe N, University of California San Francisco MS-EPIC Team, Schaefer C, McCauley JL, Cree BAC, Didonna A, Baranzini SE, Patsopoulos NA, Hauser SL, Barcellos LF, Henry RG, Oksenberg JR

CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity.

Neurology(R) neuroimmunology & neuroinflammation

Gupta S, Simic M, Sagan SA, Shepherd C, Duecker J, Sobel RA, Dandekar R, Wu GF, Wu W, Pak JE, Hauser SL, Lim W, Wilson MR, Zamvil SS

Remote Observational Research for Multiple Sclerosis: A Natural Experiment.

Neurology(R) neuroimmunology & neuroinflammation

Bove R, Poole S, Cuneo R, Gupta S, Sabatino J, Harms M, Cooper T, Rowles W, Miller N, Gomez R, Lincoln R, McPolin K, Powers K, Santaniello A, Renschen A, Bevan CJ, Gelfand JM, Goodin DS, Guo CY, Romeo AR, Hauser SL, Campbell Cree BA, UCSF MS-EPIC Team

Association of daily physical activity with brain volumes and cervical spinal cord areas in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Block VJ, Cheng S, Juwono J, Cuneo R, Kirkish G, Alexander AM, Khan M, Akula A, Caverzasi E, Papinutto N, Stern WA, Pletcher MJ, Marcus GM, Olgin JE, Hauser SL, Gelfand JM, Bove R, Cree BA, Henry RG

Neural correlates of digital measures shown by structural MRI: a post-hoc analysis of a smartphone-based remote assessment feasibility study in multiple sclerosis.

Journal of neurology

Ganzetti M, Graves JS, Holm SP, Dondelinger F, Midaglia L, Gaetano L, Craveiro L, Lipsmeier F, Bernasconi C, Montalban X, Hauser SL, Lindemann M

Differences in Age-related Retinal and Cortical Atrophy Rates in Multiple Sclerosis.

Neurology

Cordano C, Nourbakhsh B, Yiu HH, Papinutto N, Caverzasi E, Abdelhak A, Oertel FC, Beaudry-Richard A, Santaniello A, Sacco S, Bennett DJ, Gomez A, Sigurdson CJ, Hauser SL, Magliozzi R, Cree BAC, Henry RG, Green AJ

KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.

Science (New York, N.Y.)

Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM

Challenges to Longitudinal Characterization of Lower Urinary Tract Dysfunction in Multiple Sclerosis.

Multiple sclerosis and related disorders

Kaplan TB, Gopal A, Block VJ, Suskind AM, Zhao C, Polgar-Turcsanyi M, Saraceno TJ, Gomez R, Santaniello A, Consortium S, Ayoubi NE, Cree BAC, Hauser SL, Weiner H, Chitnis T, Khoury S, Bove R

Prognostic Value of Serum Neurofilament Light Chain for Disease Activity and Worsening in Patients With Relapsing Multiple Sclerosis: Results From the Phase 3 ASCLEPIOS I and II Trials.

Frontiers in immunology

Ziemssen T, Arnold DL, Alvarez E, Cross AH, Willi R, Li B, Kukkaro P, Kropshofer H, Ramanathan K, Merschhemke M, Kieseier B, Su W, Häring DA, Hauser SL, Kappos L, Kuhle J

Reply to "Spinal cord atrophy is a preclinical marker of progressive MS".

Annals of neurology

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of CaliforniaSan Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG

Efficacy and safety of ofatumumab in recently diagnosed, treatment-naive patients with multiple sclerosis: Results from ASCLEPIOS I and II.

Multiple sclerosis (Houndmills, Basingstoke, England)

Gärtner J, Hauser SL, Bar-Or A, Montalban X, Cohen JA, Cross AH, Deiva K, Ganjgahi H, Häring DA, Li B, Pingili R, Ramanathan K, Su W, Willi R, Kieseier B, Kappos L

Simultaneous assessment of regional distributions of atrophy across the neuraxis in MS patients.

NeuroImage. Clinical

Freund P, Papinutto N, Bischof A, Azzarito M, Kirkish G, Ashburner J, Thompson A, Hauser SL, Henry RG

Multiple sclerosis: two decades of progress.

The Lancet. Neurology

Cree BAC, Oksenberg JR, Hauser SL

Safety experience with continued exposure to ofatumumab in patients with relapsing forms of multiple sclerosis for up to 3.5 years.

Multiple sclerosis (Houndmills, Basingstoke, England)

Hauser SL, Cross AH, Winthrop K, Wiendl H, Nicholas J, Meuth SG, Giacomini PS, Saccà F, Mancione L, Zielman R, Bagger M, Das Gupta A, Häring DA, Jehl V, Kieseier BC, Pingili R, Stoneman D, Su W, Willi R, Kappos L

Building a Precision Medicine Delivery Platform for Clinics: The University of California, San Francisco, BRIDGE Experience.

Journal of medical Internet research

Bove R, Schleimer E, Sukhanov P, Gilson M, Law SM, Barnecut A, Miller BL, Hauser SL, Sanders SJ, Rankin KP

Search for Relativistic Magnetic Monopoles with Eight Years of IceCube Data.

Physical review letters

Abbasi R, Ackermann M, Adams J, Aguilar JA, Ahlers M, Ahrens M, Alispach C, Alves AA, Amin NM, An R, Andeen K, Anderson T, Anton G, Argüelles C, Ashida Y, Axani S, Bai X, Balagopal V A, Barbano A, Barwick SW, Bastian B, Basu V, Baur S, Bay R, Beatty JJ, Becker KH, Becker Tjus J, Bellenghi C, BenZvi S, Berley D, Bernardini E, Besson DZ, Binder G, Bindig D, Blaufuss E, Blot S, Boddenberg M, Bontempo F, Borowka J, Böser S, Botner O, Böttcher J, Bourbeau E, Bradascio F, Braun J, Bron S, Brostean-Kaiser J, Browne S, Burgman A, Burley RT, Busse RS, Campana MA, Carnie-Bronca EG, Chen C, Chen Z, Chirkin D, Choi K, Clark BA, Clark K, Classen L, Coleman A, Collin GH, Conrad JM, Coppin P, Correa P, Cowen DF, Cross R, Dappen C, Dave P, De Clercq C, DeLaunay JJ, Dembinski H, Deoskar K, Desai A, Desiati P, de Vries KD, de Wasseige G, de With M, DeYoung T, Dharani S, Diaz A, Díaz-Vélez JC, Dittmer M, Dujmovic H, Dunkman M, DuVernois MA, Dvorak E, Ehrhardt T, Eller P, Engel R, Erpenbeck H, Evans J, Evenson PA, Fan KL, Fazely AR, Feigl N, Fiedlschuster S, Fienberg AT, Filimonov K, Finley C, Fischer L, Fox D, Franckowiak A, Friedman E, Fritz A, Fürst P, Gaisser TK, Gallagher J, Ganster E, Garcia A, Garrappa S, Gerhardt L, Ghadimi A, Glaser C, Glauch T, Glüsenkamp T, Gonzalez JG, Goswami S, Grant D, Grégoire T, Griswold S, Gündüz M, Günther C, Haack C, Hallgren A, Halliday R, Halve L, Halzen F, Ha Minh M, Hanson K, Hardin J, Harnisch AA, Haungs A, Hauser S, Hebecker D, Helbing K, Henningsen F, Hettinger EC, Hickford S, Hignight J, Hill C, Hill GC, Hoffman KD, Hoffmann R, Hoinka T, Hokanson-Fasig B, Hoshina K, Huang F, Huber M, Huber T, Hultqvist K, Hünnefeld M, Hussain R, In S, Iovine N, Ishihara A, Jansson M, Japaridze GS, Jeong M, Jones BJP, Kang D, Kang W, Kang X, Kappes A, Kappesser D, Karg T, Karl M, Karle A, Katz U, Kauer M, Kellermann M, Kelley JL, Kheirandish A, Kin K, Kintscher T, Kiryluk J, Klein SR, Koirala R, Kolanoski H, Kontrimas T, Köpke L, Kopper C, Kopper S, Koskinen DJ, Koundal P, Kovacevich M, Kowalski M, Kozynets T, Kun E, Kurahashi N, Lad N, Lagunas Gualda C, Lanfranchi JL, Larson MJ, Lauber F, Lazar JP, Lee JW, Leonard K, Leszczynska A, Li Y, Lincetto M, Liu QR, Liubarska M, Lohfink E, Lozano Mariscal CJ, Lu L, Lucarelli F, Ludwig A, Luszczak W, Lyu Y, Ma WY, Madsen J, Mahn KBM, Makino Y, Mancina S, Maris IC, Maruyama R, Mase K, McElroy T, McNally F, Mead JV, Meagher K, Mechbal S, Medina A, Meier M, Meighen-Berger S, Micallef J, Mockler D, Montaruli T, Moore RW, Morse R, Moulai M, Naab R, Nagai R, Naumann U, Necker J, Nguy?n LV, Niederhausen H, Nisa MU, Nowicki SC, Obertacke Pollmann A, Oehler M, Oeyen B, Olivas A, O'Sullivan E, Pandya H, Pankova DV, Park N, Parker GK, Paudel EN, Paul L, Pérez de Los Heros C, Peters L, Peterson J, Philippen S, Pieloth D, Pieper S, Pittermann M, Pizzuto A, Plum M, Popovych Y, Porcelli A, Prado Rodriguez M, Price PB, Pries B, Przybylski GT, Raab C, Raissi A, Rameez M, Rawlins K, Rea IC, Rehman A, Reichherzer P, Reimann R, Renzi G, Resconi E, Reusch S, Rhode W, Richman M, Riedel B, Roberts EJ, Robertson S, Roellinghoff G, Rongen M, Rott C, Ruhe T, Ryckbosch D, Rysewyk Cantu D, Safa I, Saffer J, Sanchez Herrera SE, Sandrock A, Sandroos J, Santander M, Sarkar S, Sarkar S, Satalecka K, Scharf M, Schaufel M, Schieler H, Schindler S, Schlunder P, Schmidt T, Schneider A, Schneider J, Schröder FG, Schumacher L, Schwefer G, Sclafani S, Seckel D, Seunarine S, Sharma A, Shefali S, Silva M, Skrzypek B, Smithers B, Snihur R, Soedingrekso J, Soldin D, Spannfellner C, Spiczak GM, Spiering C, Stachurska J, Stamatikos M, Stanev T, Stein R, Stettner J, Steuer A, Stezelberger T, Stürwald T, Stuttard T, Sullivan GW, Taboada I, Tenholt F, Ter-Antonyan S, Tilav S, Tischbein F, Tollefson K, Tomankova L, Tönnis C, Toscano S, Tosi D, Trettin A, Tselengidou M, Tung CF, Turcati A, Turcotte R, Turley CF, Twagirayezu JP, Ty B, Unland Elorrieta MA, Valtonen-Mattila N, Vandenbroucke J, van Eijndhoven N, et al

Spinal cord atrophy predicts progressive disease in relapsing multiple sclerosis.

Annals of neurology

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of California, San Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG

Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19.

bioRxiv : the preprint server for biology

Li J, Zaslavsky M, Su Y, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Aditya Mallajosyula VV, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM

Specific hypomethylation programs underpin B cell activation in early multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Ma Q, Caillier SJ, Muzic S, University of California San Francisco MS-EPIC Team, Wilson MR, Henry RG, Cree BAC, Hauser SL, Didonna A, Oksenberg JR

Author Correction: Pan-viral serology implicates enteroviruses in acute flaccid myelitis.

Nature medicine

Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GM, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR

Safety of Ocrelizumab in Patients With Relapsing and Primary Progressive Multiple Sclerosis.

Neurology

Hauser SL, Kappos L, Montalban X, Craveiro L, Chognot C, Hughes R, Koendgen H, Pasquarelli N, Pradhan A, Prajapati K, Wolinsky JS

Electronic Health Record Technology Designed for the Clinical Encounter: MS NeuroShare.

Neurology. Clinical practice

Bove R, Bruce CA, Lunders CK, Pearce JR, Liu J, Schleimer E, Hauser SL, Stewart WF, Jones JB

A smartphone sensor-based digital outcome assessment of multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Montalban X, Graves J, Midaglia L, Mulero P, Julian L, Baker M, Schadrack J, Gossens C, Ganzetti M, Scotland A, Lipsmeier F, van Beek J, Bernasconi C, Belachew S, Lindemann M, Hauser SL

High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility.

Frontiers in immunology

Osoegawa K, Creary LE, Montero-Martín G, Mallempati KC, Gangavarapu S, Caillier SJ, Santaniello A, Isobe N, Hollenbach JA, Hauser SL, Oksenberg JR, Fernández-Vina MA

Risk of requiring a wheelchair in primary progressive multiple sclerosis: Data from the ORATORIO trial and the MSBase registry.

European journal of neurology

Butzkueven H, Spelman T, Horakova D, Hughes S, Solaro C, Izquierdo G, Kubala Havrdová E, Grand'Maison F, Prat A, Girard M, Hupperts R, Onofrj M, Lugaresi A, Taylor B, MSBase Study Group, Giovannoni G, Kappos L, Hauser SL, Montalban X, Craveiro L, Freitas R, Model F, Overell J, Muros-Le Rouzic E, Sauter A, Wang Q, Wormser D, Wolinsky JS

Risk of requiring a walking aid after 6.5 years of ocrelizumab treatment in patients with relapsing multiple sclerosis: Data from the OPERA I and OPERA II trials.

European journal of neurology

Giovannoni G, Kappos L, de Seze J, Hauser SL, Overell J, Koendgen H, Manfrini M, Wang Q, Wolinsky JS

Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis.

Brain : a journal of neurology

Kim K, Pröbstel AK, Baumann R, Dyckow J, Landefeld J, Kogl E, Madireddy L, Loudermilk R, Eggers EL, Singh S, Caillier SJ, Hauser SL, Cree BAC

Antigen Presentation by B Cells in Multiple Sclerosis.

The New England journal of medicine

Zamvil SS, Hauser SL

Ocrelizumab in relapsing and primary progressive multiple sclerosis: Pharmacokinetic and pharmacodynamic analyses of OPERA I, OPERA II and ORATORIO.

British journal of clinical pharmacology

Gibiansky E, Petry C, Mercier F, Günther A, Herman A, Kappos L, Hauser S, Yamamoto Y, Wang Q, Model F, Kletzl H

An electronic, unsupervised patient-reported Expanded Disability Status Scale for multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Romeo AR, Rowles WM, Schleimer ES, Barba P, Hsu WY, Gomez R, Santaniello A, Zhao C, Pearce JR, Jones JB, Cree BC, Hauser SL, Gelfand JM, Stewart WF, Goodin DS, Bove RM

Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis.

Science immunology

Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE

Retinal INL Thickness in Multiple Sclerosis: A Mere Marker of Neurodegeneration?

Annals of neurology

Cordano C, Yiu HH, Oertel FC, University of California, San Francisco MS-EPIC Team, Gelfand JM, Hauser SL, Cree BAC, Green AJ

Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS.

AJNR. American journal of neuroradiology

Sacco S, Caverzasi E, Papinutto N, Cordano C, Bischof A, Gundel T, Cheng S, Asteggiano C, Kirkish G, Mallot J, Stern WA, Bastianello S, Bove RM, Gelfand JM, Goodin DS, Green AJ, Waubant E, Wilson MR, Zamvil SS, Cree BA, Hauser SL, Henry RG

Role of B Cells in Multiple Sclerosis and Related Disorders.

Annals of neurology

Comi G, Bar-Or A, Lassmann H, Uccelli A, Hartung HP, Montalban X, Sørensen PS, Hohlfeld R, Hauser SL, Expert Panel of the 27th Annual Meeting of the European Charcot Foundation

Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the randomised, placebo-controlled, phase 3 trial.

The Lancet. Neurology

Wolinsky JS, Arnold DL, Brochet B, Hartung HP, Montalban X, Naismith RT, Manfrini M, Overell J, Koendgen H, Sauter A, Bennett I, Hubeaux S, Kappos L, Hauser SL

CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons.

Disease models & mechanisms

Schuster S, Heuten E, Velic A, Admard J, Synofzik M, Ossowski S, Macek B, Hauser S, Schöls L

Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans.

Scientific reports

Nakatsuka N, Patterson N, Patsopoulos NA, Altemose N, Tandon A, Beecham AH, McCauley JL, Isobe N, Hauser S, De Jager PL, Hafler DA, Oksenberg JR, Reich D

eV-Scale Sterile Neutrino Search Using Eight Years of Atmospheric Muon Neutrino Data from the IceCube Neutrino Observatory.

Physical review letters

Aartsen MG, Abbasi R, Ackermann M, Adams J, Aguilar JA, Ahlers M, Ahrens M, Alispach C, Amin NM, Andeen K, Anderson T, Ansseau I, Anton G, Argüelles C, Auffenberg J, Axani S, Bagherpour H, Bai X, Balagopal A, Barbano A, Barwick SW, Bastian B, Basu V, Baum V, Baur S, Bay R, Beatty JJ, Becker KH, Becker Tjus J, BenZvi S, Berley D, Bernardini E, Besson DZ, Binder G, Bindig D, Blaufuss E, Blot S, Bohm C, Böser S, Botner O, Böttcher J, Bourbeau E, Bourbeau J, Bradascio F, Braun J, Bron S, Brostean-Kaiser J, Burgman A, Buscher J, Busse RS, Carver T, Chen C, Cheung E, Chirkin D, Choi S, Clark BA, Clark K, Classen L, Coleman A, Collin GH, Conrad JM, Coppin P, Correa P, Cowen DF, Cross R, Dave P, De Clercq C, DeLaunay JJ, Dembinski H, Deoskar K, De Ridder S, Desai A, Desiati P, de Vries KD, de Wasseige G, de With M, DeYoung T, Dharani S, Diaz A, Díaz-Vélez JC, Dujmovic H, Dunkman M, DuVernois MA, Dvorak E, Ehrhardt T, Eller P, Engel R, Evenson PA, Fahey S, Fazely AR, Fedynitch A, Felde J, Fienberg AT, Filimonov K, Finley C, Fox D, Franckowiak A, Friedman E, Fritz A, Gaisser TK, Gallagher J, Ganster E, Garrappa S, Gerhardt L, Glauch T, Glüsenkamp T, Goldschmidt A, Gonzalez JG, Grant D, Grégoire T, Griffith Z, Griswold S, Günder M, Gündüz M, Haack C, Hallgren A, Halliday R, Halve L, Halzen F, Hanson K, Hardin J, Haungs A, Hauser S, Hebecker D, Heereman D, Heix P, Helbing K, Hellauer R, Henningsen F, Hickford S, Hignight J, Hill GC, Hoffman KD, Hoffmann R, Hoinka T, Hokanson-Fasig B, Hoshina K, Huang F, Huber M, Huber T, Hultqvist K, Hünnefeld M, Hussain R, In S, Iovine N, Ishihara A, Jansson M, Japaridze GS, Jeong M, Jones BJP, Jonske F, Joppe R, Kang D, Kang W, Kappes A, Kappesser D, Karg T, Karl M, Karle A, Katz U, Kauer M, Kellermann M, Kelley JL, Kheirandish A, Kim J, Kintscher T, Kiryluk J, Kittler T, Klein SR, Koirala R, Kolanoski H, Köpke L, Kopper C, Kopper S, Koskinen DJ, Koundal P, Kowalski M, Krings K, Krückl G, Kulacz N, Kurahashi N, Kyriacou A, Lanfranchi JL, Larson MJ, Lauber F, Lazar JP, Leonard K, Leszczynska A, Li Y, Liu QR, Lohfink E, Lozano Mariscal CJ, Lu L, Lucarelli F, Ludwig A, Lünemann J, Luszczak W, Lyu Y, Ma WY, Madsen J, Maggi G, Mahn KBM, Makino Y, Mallik P, Mancina S, Maris IC, Maruyama R, Mase K, Maunu R, McNally F, Meagher K, Medici M, Medina A, Meier M, Meighen-Berger S, Merz J, Meures T, Micallef J, Mockler D, Momenté G, Montaruli T, Moore RW, Morse R, Moulai M, Muth P, Nagai R, Naumann U, Neer G, Nguyen LV, Niederhausen H, Nisa MU, Nowicki SC, Nygren DR, Obertacke Pollmann A, Oehler M, Olivas A, O'Murchadha A, O'Sullivan E, Palczewski T, Pandya H, Pankova DV, Park N, Parker GK, Paudel EN, Peiffer P, Pérez de Los Heros C, Philippen S, Pieloth D, Pieper S, Pinat E, Pizzuto A, Plum M, Popovych Y, Porcelli A, Prado Rodriguez M, Price PB, Przybylski GT, Raab C, Raissi A, Rameez M, Rauch L, Rawlins K, Rea IC, Rehman A, Reimann R, Relethford B, Renschler M, Renzi G, Resconi E, Rhode W, Richman M, Riedel B, Robertson S, Rongen M, Rott C, Ruhe T, Ryckbosch D, Rysewyk Cantu D, Safa I, Sanchez Herrera SE, Sandrock A, Sandroos J, Santander M, Sarkar S, Sarkar S, Satalecka K, Scharf M, Schaufel M, Schieler H, Schlunder P, Schmidt T, Schneider A, Schneider J, Schröder FG, Schumacher L, Sclafani S, Seckel D, Seunarine S, Shefali S, Silva M, Smithers B, Snihur R, Soedingrekso J, Soldin D, Song M, Spiczak GM, Spiering C, Stachurska J, Stamatikos M, Stanev T, Stein R, Stettner J, Steuer A, Stezelberger T, Stokstad RG, Stößl A, Strotjohann NL, Stürwald T, Stuttard T, Sullivan GW, Taboada I, Tenholt F, Ter-Antonyan S, Terliuk A, Tilav S, Tollefson K, Tomankova L, Tönnis C, Toscano S, Tosi D, Trettin A, Tselengidou M, Tung CF, Turcati A, Turcotte R, Turley CF, Ty B, Unger E, Unland Elorrieta MA, Usner M, Vandenbroucke J, Van Driessche W, van Eijk D, van Eijndhoven N, Vannerom D, van Santen J, Verpoest S, Vraeghe M, Walck C, Wallace A, Wallraff M, Watson TB, Weaver C, Weindl A, Weiss MJ, Weldert J, Wendt C, et al

Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.

Proceedings of the National Academy of Sciences of the United States of America

Didonna A, Canto Puig E, Ma Q, Matsunaga A, Ho B, Caillier SJ, Shams H, Lee N, Hauser SL, Tan Q, Zamvil SS, Oksenberg JR

A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D

Ofatumumab versus Teriflunomide in Multiple Sclerosis.

The New England journal of medicine

Hauser SL, Bar-Or A, Cohen JA, Comi G, Correale J, Coyle PK, Cross AH, de Seze J, Leppert D, Montalban X, Selmaj K, Wiendl H, Kerloeguen C, Willi R, Li B, Kakarieka A, Tomic D, Goodyear A, Pingili R, Häring DA, Ramanathan K, Merschhemke M, Kappos L, ASCLEPIOS I and ASCLEPIOS II Trial Groups

High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display.

Brain communications

O'Donovan B, Mandel-Brehm C, Vazquez SE, Liu J, Parent AV, Anderson MS, Kassimatis T, Zekeridou A, Hauser SL, Pittock SJ, Chow E, Wilson MR, DeRisi JL

Imaging correlates of visual function in multiple sclerosis.

PloS one

Caverzasi E, Cordano C, Zhu AH, Zhao C, Bischof A, Kirkish G, Bennett DJ, Devereux M, Baker N, Inman J, Yiu HH, Papinutto N, Gelfand JM, Cree BAC, Hauser SL, Henry RG, Green AJ

Five years of ocrelizumab in relapsing multiple sclerosis: OPERA studies open-label extension.

Neurology

Hauser SL, Kappos L, Arnold DL, Bar-Or A, Brochet B, Naismith RT, Traboulsee A, Wolinsky JS, Belachew S, Koendgen H, Levesque V, Manfrini M, Model F, Hubeaux S, Mehta L, Montalban X

Treatment of Multiple Sclerosis: A Review.

The American journal of medicine

Hauser SL, Cree BAC

A Precision Medicine Tool for Patients With Multiple Sclerosis (the Open MS BioScreen): Human-Centered Design and Development.

Journal of medical Internet research

Schleimer E, Pearce J, Barnecut A, Rowles W, Lizee A, Klein A, Block VJ, Santaniello A, Renschen A, Gomez R, Keshavan A, Gelfand JM, Henry RG, Hauser SL, Bove R

Serum antibodies to phosphatidylcholine in MS.

Neurology(R) neuroimmunology & neuroinflammation

Sádaba MC, Rothhammer V, Muñoz Ú, Sebal C, Escudero E, Kivisäkk P, Garcia Sanchez MI, Izquierdo G, Hauser SL, Baranzini SE, Oksenberg JR, Álvarez-Lafuente R, Bakshi R, Weiner HL, Quintana FJ

Brain MRI Predicts Worsening Multiple Sclerosis Disability over 5 Years in the SUMMIT Study.

Journal of neuroimaging : official journal of the American Society of Neuroimaging

Bakshi R, Healy BC, Dupuy SL, Kirkish G, Khalid F, Gundel T, Asteggiano C, Yousuf F, Alexander A, Hauser SL, Weiner HL, Henry RG, SUMMIT consortium

Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Sabatino JJ, Wilson MR, Calabresi PA, Hauser SL, Schneck JP, Zamvil SS

Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years.

JAMA neurology

Cantó E, Barro C, Zhao C, Caillier SJ, Michalak Z, Bove R, Tomic D, Santaniello A, Häring DA, Hollenbach J, Henry RG, Cree BAC, Kappos L, Leppert D, Hauser SL, Benkert P, Oksenberg JR, Kuhle J

Pan-viral serology implicates enteroviruses in acute flaccid myelitis.

Nature medicine

Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GA, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR

Correction: Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

Journal of medical Internet research

Midaglia L, Mulero P, Montalban X, Graves J, Hauser SL, Julian L, Baker M, Schadrack J, Gossens C, Scotland A, Lipsmeier F, van Beek J, Bernasconi C, Belachew S, Lindemann M

Telomere Length Is Associated with Disability Progression in Multiple Sclerosis.

Annals of neurology

Krysko KM, Henry RG, Cree BAC, Lin J, University of California, San Francisco MS-EPIC Team, Caillier S, Santaniello A, Zhao C, Gomez R, Bevan C, Smith DL, Stern W, Kirkish G, Hauser SL, Oksenberg JR, Graves JS

Intersubject Variability and Normalization Strategies for Spinal Cord Total Cross-Sectional and Gray Matter Areas.

Journal of neuroimaging : official journal of the American Society of Neuroimaging

Papinutto N, Asteggiano C, Bischof A, Gundel TJ, Caverzasi E, Stern WA, Bastianello S, Hauser SL, Henry RG

Contribution of normal aging to brain atrophy in MS.

Neurology(R) neuroimmunology & neuroinflammation

Azevedo CJ, Cen SY, Jaberzadeh A, Zheng L, Hauser SL, Pelletier D

Onset of clinical and MRI efficacy of ocrelizumab in relapsing multiple sclerosis.

Neurology

Barkhof F, Kappos L, Wolinsky JS, Li DKB, Bar-Or A, Hartung HP, Belachew S, Han J, Julian L, Sauter A, Napieralski J, Koendgen H, Hauser SL

Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis.

Brain : a journal of neurology

Elliott C, Belachew S, Wolinsky JS, Hauser SL, Kappos L, Barkhof F, Bernasconi C, Fecker J, Model F, Wei W, Arnold DL

Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

Journal of medical Internet research

Midaglia L, Mulero P, Montalban X, Graves J, Hauser SL, Julian L, Baker M, Schadrack J, Gossens C, Scotland A, Lipsmeier F, van Beek J, Bernasconi C, Belachew S, Lindemann M

Opposing T cell responses in experimental autoimmune encephalomyelitis.

Nature

Saligrama N, Zhao F, Sikora MJ, Serratelli WS, Fernandes RA, Louis DM, Yao W, Ji X, Idoyaga J, Mahajan VB, Steinmetz LM, Chien YH, Hauser SL, Oksenberg JR, Garcia KC, Davis MM

Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.

Journal of autoimmunity

Didonna A, Cantó E, Shams H, Isobe N, Zhao C, Caillier SJ, Condello C, Yamate-Morgan H, Tiwari-Woodruff SK, Mofrad MRK, Hauser SL, Oksenberg JR

Nucleic Acid-Based Therapeutics Relevant to Neuroimmune Conditions.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Greenfield AL, Hauser SL

Silent progression in disease activity-free relapsing multiple sclerosis.

Annals of neurology

Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS, Gelfand JM, Graves J, Green AJ, Wilson MR, Zamvil SS, Zhao C, Gomez R, Ragan NR, Rush GQ, Barba P, Santaniello A, Baranzini SE, Oksenberg JR, Henry RG, Hauser SL

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease.

Proceedings of the National Academy of Sciences of the United States of America

Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, Hauser SL, Fernandez-Viña M, Oksenberg JR

Longitudinally persistent cerebrospinal fluid B cells can resist treatment in multiple sclerosis.

JCI insight

Greenfield AL, Dandekar R, Ramesh A, Eggers EL, Wu H, Laurent S, Harkin W, Pierson NS, Weber MS, Henry RG, Bischof A, Cree BA, Hauser SL, Wilson MR, von Büdingen HC

Ocrelizumab efficacy in subgroups of patients with relapsing multiple sclerosis.

Journal of neurology

Turner B, Cree BAC, Kappos L, Montalban X, Papeix C, Wolinsky JS, Buffels R, Fiore D, Garren H, Han J, Hauser SL

B-Cell Therapies in Multiple Sclerosis.

Cold Spring Harbor perspectives in medicine

Sabatino JJ, Zamvil SS, Hauser SL

Ocrelizumab infusion experience in patients with relapsing and primary progressive multiple sclerosis: Results from the phase 3 randomized OPERA I, OPERA II, and ORATORIO studies.

Multiple sclerosis and related disorders

Mayer L, Kappos L, Racke MK, Rammohan K, Traboulsee A, Hauser SL, Julian L, Köndgen H, Li C, Napieralski J, Zheng H, Wolinsky JS

pRNFL as a marker of disability worsening in the medium/long term in patients with MS.

Neurology(R) neuroimmunology & neuroinflammation

Cordano C, Nourbakhsh B, Devereux M, Damotte V, Bennett D, Hauser SL, Cree BAC, Gelfand JM, Green AJ

Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions.

Multiple sclerosis (Houndmills, Basingstoke, England)

Elliott C, Wolinsky JS, Hauser SL, Kappos L, Barkhof F, Bernasconi C, Wei W, Belachew S, Arnold DL

Body mass index, but not vitamin D status, is associated with brain volume change in MS.

Neurology

Mowry EM, Azevedo CJ, McCulloch CE, Okuda DT, Lincoln RR, Waubant E, Hauser SL, Pelletier D

Evaluation of no evidence of progression or active disease (NEPAD) in patients with primary progressive multiple sclerosis in the ORATORIO trial.

Annals of neurology

Wolinsky JS, Montalban X, Hauser SL, Giovannoni G, Vermersch P, Bernasconi C, Deol-Bhullar G, Garren H, Chin P, Belachew S, Kappos L

Toward a low-cost, in-home, telemedicine-enabled assessment of disability in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Bove R, Bevan C, Crabtree E, Zhao C, Gomez R, Garcha P, Morrissey J, Dierkhising J, Green AJ, Hauser SL, Cree BA, Wallin MT, Gelfand JM

Identification of MS-specific serum miRNAs in an international multicenter study.

Neurology(R) neuroimmunology & neuroinflammation

Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R

Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis.

Annals of neurology

Jia X, Madireddy L, Caillier S, Santaniello A, Esposito F, Comi G, Stuve O, Zhou Y, Taylor B, Kilpatrick T, Martinelli-Boneschi F, Cree BAC, Oksenberg JR, Hauser SL, Baranzini SE

Multiple Sclerosis: B Cells Take Center Stage.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Pröbstel AK, Hauser SL

Rituximab before and during pregnancy: A systematic review, and a case series in MS and NMOSD.

Neurology(R) neuroimmunology & neuroinflammation

Das G, Damotte V, Gelfand JM, Bevan C, Cree BAC, Do L, Green AJ, Hauser SL, Bove R

No evidence of disease activity (NEDA) analysis by epochs in patients with relapsing multiple sclerosis treated with ocrelizumab vs interferon beta-1a.

Multiple sclerosis journal - experimental, translational and clinical

Havrdová E, Arnold DL, Bar-Or A, Comi G, Hartung HP, Kappos L, Lublin F, Selmaj K, Traboulsee A, Belachew S, Bennett I, Buffels R, Garren H, Han J, Julian L, Napieralski J, Hauser SL, Giovannoni G

Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients.

Journal of neuroinflammation

Canto E, Isobe N, Didonna A, MS-EPIC Study Group, Hauser SL, Oksenberg JR

Thalamic atrophy in multiple sclerosis: A magnetic resonance imaging marker of neurodegeneration throughout disease.

Annals of neurology

Azevedo CJ, Cen SY, Khadka S, Liu S, Kornak J, Shi Y, Zheng L, Hauser SL, Pelletier D

Harnessing electronic medical records to advance research on multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA

B-cell Therapy for Multiple Sclerosis: Entering an era.

Annals of neurology

Greenfield AL, Hauser SL

Ovarian aging is associated with gray matter volume and disability in women with MS.

Neurology

Graves JS, Henry RG, Cree BAC, Lambert-Messerlian G, Greenblatt RM, Waubant E, Cedars MI, Zhu A, Bacchetti P, Hauser SL, Oksenberg JR

Diagnosing multiple sclerosis: art and science.

The Lancet. Neurology

Bove RM, Hauser SL

Advances in Imaging Multiple Sclerosis.

Seminars in neurology

Bischof A, Caverzasi E, Cordano C, Hauser SL, Henry RG

Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients.

JCI insight

Eggers EL, Michel BA, Wu H, Wang SZ, Bevan CJ, Abounasr A, Pierson NS, Bischof A, Kazer M, Leitner E, Greenfield AL, Demuth S, Wilson MR, Henry RG, Cree BA, Hauser SL, von Büdingen HC

Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series.

Neurology

Gelfand JM, Bradshaw MJ, Stern BJ, Clifford DB, Wang Y, Cho TA, Koth LL, Hauser SL, Dierkhising J, Vu N, Sriram S, Moses H, Bagnato F, Kaufmann JA, Ammah DJ, Yohannes TH, Hamblin MJ, Venna N, Green AJ, Pawate S

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial.

Lancet (London, England)

Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR

Ocrelizumab and Other CD20+ B-Cell-Depleting Therapies in Multiple Sclerosis.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Gelfand JM, Cree BAC, Hauser SL

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models.

Proceedings of the National Academy of Sciences of the United States of America

Cekanaviciute E, Yoo BB, Runia TF, Debelius JW, Singh S, Nelson CA, Kanner R, Bencosme Y, Lee YK, Hauser SL, Crabtree-Hartman E, Sand IK, Gacias M, Zhu Y, Casaccia P, Cree BAC, Knight R, Mazmanian SK, Baranzini SE

SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts.

Multiple sclerosis (Houndmills, Basingstoke, England)

Bove R, Chitnis T, Cree BA, Tintoré M, Naegelin Y, Uitdehaag BM, Kappos L, Khoury SJ, Montalban X, Hauser SL, Weiner HL, SUMMIT Consortium

Population Modeling Integrating Pharmacokinetics, Pharmacodynamics, Pharmacogenetics, and Clinical Outcome in Patients With Sunitinib-Treated Cancer.

CPT: pharmacometrics & systems pharmacology

Diekstra MH, Fritsch A, Kanefendt F, Swen JJ, Moes D, Sörgel F, Kinzig M, Stelzer C, Schindele D, Gauler T, Hauser S, Houtsma D, Roessler M, Moritz B, Mross K, Bergmann L, Oosterwijk E, Kiemeney LA, Guchelaar HJ, Jaehde U

STAT [editorial]

3 ways the VA can usher in the future of health care and research.

Hauser SL, VanLeeuwen J-E.

Ocrelizumab in Primary Progressive and Relapsing Multiple Sclerosis.

The New England journal of medicine

Hauser SL, Belachew S, Kappos L

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.

The New England journal of medicine

Hauser SL, Bar-Or A, Comi G, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Montalban X, Rammohan KW, Selmaj K, Traboulsee A, Wolinsky JS, Arnold DL, Klingelschmitt G, Masterman D, Fontoura P, Belachew S, Chin P, Mairon N, Garren H, Kappos L, OPERA I and OPERA II Clinical Investigators

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.

The New England journal of medicine

Montalban X, Hauser SL, Kappos L, Arnold DL, Bar-Or A, Comi G, de Seze J, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Rammohan KW, Selmaj K, Traboulsee A, Sauter A, Masterman D, Fontoura P, Belachew S, Garren H, Mairon N, Chin P, Wolinsky JS, ORATORIO Clinical Investigators

Onset of secondary progressive MS after long-term rituximab therapy - a case report.

Annals of clinical and translational neurology

von Büdingen HC, Bischof A, Eggers EL, Wang S, Bevan CJ, Cree BA, Henry RG, Hauser SL

Long-term evolution of multiple sclerosis disability in the treatment era.

Annals of neurology

Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies.

Neurology. Genetics

George MF, Briggs FB, Shao X, Gianfrancesco MA, Kockum I, Harbo HF, Celius EG, Bos SD, Hedström A, Shen L, Bernstein A, Alfredsson L, Hillert J, Olsson T, Patsopoulos NA, De Jager PL, Oturai AB, Søndergaard HB, Sellebjerg F, Sorensen PS, Gomez R, Caillier SJ, Cree BA, Oksenberg JR, Hauser SL, D'Alfonso S, Leone MA, Martinelli Boneschi F, Sorosina M, van der Mei I, Taylor BV, Zhou Y, Schaefer C, Barcellos LF

Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis.

JAMA neurology

Isobe N, Keshavan A, Gourraud PA, Zhu AH, Datta E, Schlaeger R, Caillier SJ, Santaniello A, Lizée A, Himmelstein DS, Baranzini SE, Hollenbach J, Cree BA, Hauser SL, Oksenberg JR, Henry RG

An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma.

Oncogene

Iltzsche F, Simon K, Stopp S, Pattschull G, Francke S, Wolter P, Hauser S, Murphy DJ, Garcia P, Rosenwald A, Gaubatz S

Power estimation for non-standardized multisite studies.

NeuroImage

Keshavan A, Paul F, Beyer MK, Zhu AH, Papinutto N, Shinohara RT, Stern W, Amann M, Bakshi R, Bischof A, Carriero A, Comabella M, Crane JC, D'Alfonso S, Demaerel P, Dubois B, Filippi M, Fleischer V, Fontaine B, Gaetano L, Goris A, Graetz C, Gröger A, Groppa S, Hafler DA, Harbo HF, Hemmer B, Jordan K, Kappos L, Kirkish G, Llufriu S, Magon S, Martinelli-Boneschi F, McCauley JL, Montalban X, Mühlau M, Pelletier D, Pattany PM, Pericak-Vance M, Cournu-Rebeix I, Rocca MA, Rovira A, Schlaeger R, Saiz A, Sprenger T, Stecco A, Uitdehaag BMJ, Villoslada P, Wattjes MP, Weiner H, Wuerfel J, Zimmer C, Zipp F, International Multiple Sclerosis Genetics Consortium. Electronic address: [email protected], Hauser SL, Oksenberg JR, Henry RG

Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis.

International journal of epidemiology

Khankhanian P, Cozen W, Himmelstein DS, Madireddy L, Din L, van den Berg A, Matsushita T, Glaser SL, Moré JM, Smedby KE, Baranzini SE, Mack TM, Lizée A, de Sanjosé S, Gourraud PA, Nieters A, Hauser SL, Cocco P, Maynadié M, Foretová L, Staines A, Delahaye-Sourdeix M, Li D, Bhatia S, Melbye M, Onel K, Jarrett R, McKay JD, Oksenberg JR, Hjalgrim H

A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome.

Human molecular genetics

Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, Oksenberg JR

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Nature genetics

Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J, Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CCA, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G

Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis.

JAMA neurology

Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG

Genetic contribution to multiple sclerosis risk among Ashkenazi Jews.

BMC medical genetics

Khankhanian P, Matsushita T, Madireddy L, Lizée A, Din L, Moré JM, Gourraud PA, Hauser SL, Baranzini SE, Oksenberg JR

Mitochondrial DNA sequence variation in multiple sclerosis.

Neurology

Tranah GJ, Santaniello A, Caillier SJ, D'Alfonso S, Martinelli Boneschi F, Hauser SL, Oksenberg JR

Advancing ethical neuroscience.

Annals of neurology

Hauser SL

Percutaneous CT-Guided Radiofrequency Ablation of Solitary Small Renal Masses: A Single Center Experience.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

Pieper CC, Fischer S, Strunk H, Meyer C, Thomas D, Willinek WA, Hauser S, Nadal J, Schild H, Wilhelm K

An ImmunoChip study of multiple sclerosis risk in African Americans.

Brain : a journal of neurology

Isobe N, Madireddy L, Khankhanian P, Matsushita T, Caillier SJ, Moré JM, Gourraud PA, McCauley JL, Beecham AH, International Multiple Sclerosis Genetics Consortium, Piccio L, Herbert J, Khan O, Cohen J, Stone L, Santaniello A, Cree BA, Onengut-Gumuscu S, Rich SS, Hauser SL, Sawcer S, Oksenberg JR

Genetic associations with brain cortical thickness in multiple sclerosis.

Genes, brain, and behavior

Matsushita T, Madireddy L, Sprenger T, Khankhanian P, Magon S, Naegelin Y, Caverzasi E, Lindberg RL, Kappos L, Hauser SL, Oksenberg JR, Henry R, Pelletier D, Baranzini SE

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.

Nature genetics

Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S, International Inflammatory Bowel Disease Genetics Consortium, Australia and New Zealand IBDGC, Belgium IBD Genetics Consortium, Italian Group for IBD Genetic Consortium, NIDDK Inflammatory Bowel Disease Genetics Consortium, United Kingdom IBDGC, Wellcome Trust Case Control Consortium, Quebec IBD Genetics Consortium, Daly MJ, Van Steen K, Duerr RH, Barrett JC, McGovern DP, Schumm LP, Traherne JA, Carrington MN, Kosmoliaptsis V, Karlsen TH, Franke A, Rioux JD

2D phase-sensitive inversion recovery imaging to measure in vivo spinal cord gray and white matter areas in clinically feasible acquisition times.

Journal of magnetic resonance imaging : JMRI

Papinutto N, Schlaeger R, Panara V, Caverzasi E, Ahn S, Johnson KJ, Zhu AH, Stern WA, Laub G, Hauser SL, Henry RG

The Charcot Lecture | beating MS: a story of B cells, with twists and turns.

Multiple sclerosis (Houndmills, Basingstoke, England)

Hauser SL

Precision medicine in chronic disease management: The multiple sclerosis BioScreen.

Annals of neurology

Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL

Spinal cord gray matter atrophy correlates with multiple sclerosis disability.

Annals of neurology

Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG

Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.

Science translational medicine

Palanichamy A, Apeltsin L, Kuo TC, Sirota M, Wang S, Pitts SJ, Sundar PD, Telman D, Zhao LZ, Derstine M, Abounasr A, Hauser SL, von Büdingen HC

In vivo evidence of glutamate toxicity in multiple sclerosis.

Annals of neurology

Azevedo CJ, Kornak J, Chu P, Sampat M, Okuda DT, Cree BA, Nelson SJ, Hauser SL, Pelletier D

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

Nature medicine

Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJM, Green A, Hauser SL, Chan JR

HLA diversity in the 1000 genomes dataset.

PloS one

Gourraud PA, Khankhanian P, Cereb N, Yang SY, Feolo M, Maiers M, Rioux JD, Hauser S, Oksenberg J

Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis.

JAMA neurology

Llufriu S, Kornak J, Ratiney H, Oh J, Brenneman D, Cree BA, Sampat M, Hauser SL, Nelson SJ, Pelletier D

Rituximab efficiently depletes increased CD20-expressing T cells in multiple sclerosis patients.

Journal of immunology (Baltimore, Md. : 1950)

Palanichamy A, Jahn S, Nickles D, Derstine M, Abounasr A, Hauser SL, Baranzini SE, Leppert D, von Büdingen HC

MHC associations with clinical and autoantibody manifestations in European SLE.

Genes and immunity

Morris DL, Fernando MM, Taylor KE, Chung SA, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, Langefeld CD, Noble JA, Rioux JD, Seldin MF, Systemic Lupus Erythematosus Genetics Consortium, Vyse TJ, Criswell LA

In multiple sclerosis, oligoclonal bands connect to peripheral B-cell responses.

Annals of neurology

Bankoti J, Apeltsin L, Hauser SL, Allen S, Albertolle ME, Witkowska HE, von Büdingen HC

Quo vadis? Peering into the future.

Annals of neurology

Hauser SL, Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg JR

Have the Annals editors added value?

Annals of neurology

Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg J, Stewart A, Hauser SL

Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Harbo HF, Isobe N, Berg-Hansen P, Bos SD, Caillier SJ, Gustavsen MW, Mero IL, Celius EG, Hauser SL, Oksenberg JR, Gourraud PA

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Nature genetics

Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF, Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R, Søndergaard HB, Baker A, Band G, Baranzini SE, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TM, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BA, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud PA, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelcic I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppä V, Liberatore G, Lie BA, Lill CM, Lindén M, Link J, Luessi F, Lycke J, Macciardi F, Männistö S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero IL, Mescheriakova J, Moutsianas L, Myhr KM, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL

Blockbusters for cheap? The difficulties surrounding generic biologics.

Annals of neurology

Josephson SA, Johnston SC, Hauser SL

Multiple sclerosis: Prospects and promise.

Annals of neurology

Hauser SL, Chan JR, Oksenberg JR

Genetic burden in multiple sclerosis families.

Genes and immunity

Isobe N, Damotte V, Re VL, Ban M, Pappas D, Guillot-Noel L, Rebeix I, Compston A, Mack T, Cozen W, Fontaine B, Hauser SL, Oksenberg JR, Sawcer S, Gourraud PA

Neurology: violence at home.

Annals of neurology

Hauser SL, Johnston SC

Living in the time of sequestration.

Annals of neurology

Hauser SL, Johnston SC

Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity.

The Journal of experimental medicine

Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Pekarek K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini SE

Genetic risk variants in African Americans with multiple sclerosis.

Neurology

Isobe N, Gourraud PA, Harbo HF, Caillier SJ, Santaniello A, Khankhanian P, Maiers M, Spellman S, Cereb N, Yang S, Pando MJ, Piccio L, Cross AH, De Jager PL, Cree BA, Hauser SL, Oksenberg JR

Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls.

Human molecular genetics

Nickles D, Chen HP, Li MM, Khankhanian P, Madireddy L, Caillier SJ, Santaniello A, Cree BA, Pelletier D, Hauser SL, Oksenberg JR, Baranzini SE

The neurologic revolving door: time to pay attention to readmissions.

Annals of neurology

Josephson SA, Johnston SC, Hauser SL

Big neuroscience.

Annals of neurology

Hauser SL, Johnston SC

Multiple sclerosis: monotherapy rules.

Annals of neurology

Hauser SL, Josephson SA, Johnston SC

No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis.

Annals of neurology

Ban M, Caillier S, Mero IL, Myhr KM, Celius EG, Aarseth J, Torkildsen Ø, Harbo HF, Oksenberg J, Hauser SL, Sawcer S, Compston A

A genome-wide association study of brain lesion distribution in multiple sclerosis.

Brain : a journal of neurology

Gourraud PA, Sdika M, Khankhanian P, Henry RG, Beheshtian A, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D, Baranzini SE

Are relative value units hurting healthcare?

Annals of neurology

Johnston SC, Josephson SA, Hauser SL

DSM-V: psychodrama on the public stage.

Annals of neurology

Hauser SL, Johnston SC

Reply to Dr Sethi.

Annals of neurology

Hauser SL

Copy number variation in pediatric multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

McElroy JP, Krupp LB, Johnson BA, McCauley JL, Qi Z, Caillier SJ, Gourraud PA, Yu J, Nathanson L, Belman AL, Hauser SL, Waubant E, Hedges DJ, Oksenberg JR

Electronic medical records and the academic neurologist: when carrots turn into sticks.

Annals of neurology

Josephson SA, Johnston SC, Hauser SL

B cell exchange across the blood-brain barrier in multiple sclerosis.

The Journal of clinical investigation

von Büdingen HC, Kuo TC, Sirota M, van Belle CJ, Apeltsin L, Glanville J, Cree BA, Gourraud PA, Schwartzburg A, Huerta G, Telman D, Sundar PD, Casey T, Cox DR, Hauser SL

Deciphering the signature injury.

Annals of neurology

Hauser SL, Josephson SA, Johnston SC

Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.

American journal of human genetics

Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, International MHC and Autoimmunity Genetics Network, Langefeld CD, Noble JA, Rioux JD, Seldin MF, Systemic Lupus Erythematosus Genetics Consortium, Criswell LA, Vyse TJ

Healthcare costs: Eden's apple?

Annals of neurology

Johnston SC, Hauser SL

In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing.

BMC genomics

Nickles D, Madireddy L, Yang S, Khankhanian P, Lincoln S, Hauser SL, Oksenberg JR, Baranzini SE

Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis.

Annals of neurology

Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D

The genetics of multiple sclerosis: an up-to-date review.

Immunological reviews

Gourraud PA, Harbo HF, Hauser SL, Baranzini SE

Florbetapir: knowing one's future.

Annals of neurology

Hauser SL, Josephson SA, Johnston SC

Multiple sclerosis drugs: sticker shock.

Annals of neurology

Hauser SL, Johnston SC

Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci.

Molecular autism

Hedges DJ, Hamilton-Nelson KL, Sacharow SJ, Nations L, Beecham GW, Kozhekbaeva ZM, Butler BL, Cukier HN, Whitehead PL, Ma D, Jaworski JM, Nathanson L, Lee JM, Hauser SL, Oksenberg JR, Cuccaro ML, Haines JL, Gilbert JR, Pericak-Vance MA

The neurological exam: striking a nerve.

Annals of neurology

Johnston SC, Hauser SL

Modern care for neurological problems must address waste.

Annals of neurology

Johnston SC, Hauser SL

Color vision is strongly associated with retinal thinning in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Villoslada P, Cuneo A, Gelfand J, Hauser SL, Green A

Fighting decision fatigue.

Annals of neurology

Stewart AF, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg JR, Johnston SC, Hauser SL

Decoding multiple sclerosis.

Annals of neurology

Oksenberg JR, Hauser SL

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

Annals of neurology

Patsopoulos NA, Bayer Pharma MS Genetics Working Group, Steering Committees of Studies Evaluating IFNß-1b and a CCR1-Antagonist, ANZgene Consortium, GeneMSA, International Multiple Sclerosis Genetics Consortium, Esposito F, Reischl J, Lehr S, Bauer D, Heubach J, Sandbrink R, Pohl C, Edan G, Kappos L, Miller D, Montalbán J, Polman CH, Freedman MS, Hartung HP, Arnason BG, Comi G, Cook S, Filippi M, Goodin DS, Jeffery D, O'Connor P, Ebers GC, Langdon D, Reder AT, Traboulsee A, Zipp F, Schimrigk S, Hillert J, Bahlo M, Booth DR, Broadley S, Brown MA, Browning BL, Browning SR, Butzkueven H, Carroll WM, Chapman C, Foote SJ, Griffiths L, Kermode AG, Kilpatrick TJ, Lechner-Scott J, Marriott M, Mason D, Moscato P, Heard RN, Pender MP, Perreau VM, Perera D, Rubio JP, Scott RJ, Slee M, Stankovich J, Stewart GJ, Taylor BV, Tubridy N, Willoughby E, Wiley J, Matthews P, Boneschi FM, Compston A, Haines J, Hauser SL, McCauley J, Ivinson A, Oksenberg JR, Pericak-Vance M, Sawcer SJ, De Jager PL, Hafler DA, de Bakker PI

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation.

Proceedings of the National Academy of Sciences of the United States of America

Glanville J, Kuo TC, von Büdingen HC, Guey L, Berka J, Sundar PD, Huerta G, Mehta GR, Oksenberg JR, Hauser SL, Cox DR, Rajpal A, Pons J

Benefits of medical research: Hollywood weighs in.

Annals of neurology

Hauser SL, Johnston SC

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial.

Lancet (London, England)

Kappos L, Li D, Calabresi PA, O'Connor P, Bar-Or A, Barkhof F, Yin M, Leppert D, Glanzman R, Tinbergen J, Hauser SL

Global clinical trials: challenges ahead.

Annals of neurology

Hauser SL, Johnston SC

Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410.

Journal of the National Cancer Institute

Curran WJ, Paulus R, Langer CJ, Komaki R, Lee JS, Hauser S, Movsas B, Wasserman T, Rosenthal SA, Gore E, Machtay M, Sause W, Cox JD

Waking up to narcolepsy.

Annals of neurology

Hauser SL, Johnston SC

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Nature

Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Martinelli Boneschi F, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BA, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PI, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SF, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung HP, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppä V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero IL, Mihalova T, Montalban X, Mottershead J, Myhr KM, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux JD, Rodegher M, Roesner S, Rubio JP, Rückert IM, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PM, Smestad C, Sørensen PS, Søndergaard HB, Stankovich J, Strange RC, Sulonen AM, Sundqvist E, Syvänen AC, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CN, Wichmann HE, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A

Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring.

The Lancet. Neurology

Kappos L, Bates D, Edan G, Eraksoy M, Garcia-Merino A, Grigoriadis N, Hartung HP, Havrdová E, Hillert J, Hohlfeld R, Kremenchutzky M, Lyon-Caen O, Miller A, Pozzilli C, Ravnborg M, Saida T, Sindic C, Vass K, Clifford DB, Hauser S, Major EO, O'Connor PW, Weiner HL, Clanet M, Gold R, Hirsch HH, Radü EW, Sørensen PS, King J

SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients.

Genes and immunity

McElroy JP, Isobe N, Gourraud PA, Caillier SJ, Matsushita T, Kohriyama T, Miyamoto K, Nakatsuji Y, Miki T, Hauser SL, Oksenberg JR, Kira J

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex.

Human molecular genetics

Zuvich RL, Bush WS, McCauley JL, Beecham AH, De Jager PL, International Multiple Sclerosis Genetics Consortium, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Sawcer SJ, Pericak-Vance MA, Barcellos LF, Mortlock DP, Haines JL

Vitamin D in African Americans with multiple sclerosis.

Neurology

Gelfand JM, Cree BA, McElroy J, Oksenberg J, Green R, Mowry EM, Miller JW, Hauser SL, Green AJ

Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability.

Multiple sclerosis (Houndmills, Basingstoke, England)

Roosendaal SD, Bendfeldt K, Vrenken H, Polman CH, Borgwardt S, Radue EW, Kappos L, Pelletier D, Hauser SL, Matthews PM, Barkhof F, Geurts JJ

The NIH shuffle, NCATS, and neurology.

Annals of neurology

Johnston SC, Hauser SL

Enhancing ties between academia and industry to improve health.

Nature medicine

Johnston SC, Hauser SL, Desmond-Hellmann S

Extraordinary claims require extraordinary evidence.

Annals of neurology

Hauser SL, Johnston SC

Scientific literacy and the media.

Annals of neurology

Hauser SL, Johnston SC

A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility.

Genes and immunity

Bush WS, McCauley JL, DeJager PL, Dudek SM, Hafler DA, Gibson RA, Matthews PM, Kappos L, Naegelin Y, Polman CH, Hauser SL, Oksenberg J, Haines JL, Ritchie MD, International Multiple Sclerosis Genetics Consortium

Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.

Genome medicine

Wang JH, Pappas D, De Jager PL, Pelletier D, de Bakker PI, Kappos L, Polman CH, Chibnik LB, Hafler DA, Matthews PM, Hauser SL, Baranzini SE, Oksenberg JR

Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.

Annals of neurology

Gourraud PA, McElroy JP, Caillier SJ, Johnson BA, Santaniello A, Hauser SL, Oksenberg JR

Neurologic education 2011: new challenges and opportunities.

Annals of neurology

Josephson SA, Hauser SL

Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset.

BMC genomics

Khankhanian P, Gourraud PA, Caillier SJ, Santaniello A, Hauser SL, Baranzini SE, Oksenberg JR

Malignant middle cerebral artery stroke: Where ischemia meets the scalpel.

Annals of neurology

Josephson SA, Hauser SL, Johnston SC

Fred Plum (1924-2010) and the founding of the Annals of Neurology.

Annals of neurology

Hauser SL, Johnston SC

Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.

Brain : a journal of neurology

Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D

Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals.

Human molecular genetics

Briggs FB, Bartlett SE, Goldstein BA, Wang J, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, International Multiple Sclerosis Genetics Consortium, Barcellos LF

The challenge of publishing newsworthy epidemiology.

Annals of neurology

Johnston SC, Hauser SL

4-aminopyridine: new life for an old drug.

Annals of neurology

Hauser SL, Johnston SC

A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.

PloS one

Cree BA, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, Sawcer SJ, Oksenberg JR, Hauser SL, IMAGEN, IMSGC

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis.

Genes and immunity

Ban M, McCauley JL, Zuvich R, Baker A, Bergamaschi L, Cox M, Kemppinen A, D'Alfonso S, Guerini FR, Lechner-Scott J, Dudbridge F, Wason J, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, Sexton D, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines J, Compston A, Sawcer S

Variation within DNA repair pathway genes and risk of multiple sclerosis.

American journal of epidemiology

Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium

Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis.

Nature genetics

International Multiple Sclerosis Genetics Consortium (IMSGC), Booth DR, Heard RN, Stewart GJ, Cox M, Scott RJ, Lechner-Scott J, Goris A, Dobosi R, Dubois B, Saarela J, Leppä V, Peltonen L, Pirttila T, Cournu-Rebeix I, Fontaine B, Bergamaschi L, D'Alfonso S, Leone M, Lorentzen AR, Harbo HF, Celius EG, Spurkland A, Link J, Kockum I, Olsson T, Hillert J, Ban M, Baker A, Kemppinen A, Sawcer S, Compston A, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, McCauley JL, Pericak-Vance MA, Oksenberg JR, Hauser SL, Sexton D, Haines J

Mapping the human genome with newfound precision.

Annals of neurology

Oksenberg JR, Hauser SL

[Urethral reconstructive surgery].

Der Urologe. Ausg. A

Hauser S, Fechner G, Ellinger J, Müller SC

Refining the association of MHC with multiple sclerosis in African Americans.

Human molecular genetics

McElroy JP, Cree BA, Caillier SJ, Gregersen PK, Herbert J, Khan OA, Freudenberg J, Lee A, Bridges SL, Hauser SL, Oksenberg JR, Gourraud PA

Supply does not satisfy demand in child neurology.

Annals of neurology

Ferriero DM, Hauser SL

Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.

Nature

Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF

Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration.

Brain : a journal of neurology

Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

Annals of neurology

Bar-Or A, Fawaz L, Fan B, Darlington PJ, Rieger A, Ghorayeb C, Calabresi PA, Waubant E, Hauser SL, Zhang J, Smith CH

Neuroreconciliation and the health care debate.

Annals of neurology

Hauser SL, Johnston SC, Stewart AF

CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis.

Human molecular genetics

Bronson PG, Caillier S, Ramsay PP, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Sawcer SJ, Pericak-Vance MA, Haines JL, International Multiple Sclerosis Genetics Consortium, Hauser SL, Oksenberg JR, Barcellos LF

Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.

American journal of human genetics

Jakkula E, Leppä V, Sulonen AM, Varilo T, Kallio S, Kemppinen A, Purcell S, Koivisto K, Tienari P, Sumelahti ML, Elovaara I, Pirttilä T, Reunanen M, Aromaa A, Oturai AB, Søndergaard HB, Harbo HF, Mero IL, Gabriel SB, Mirel DB, Hauser SL, Kappos L, Polman C, De Jager PL, Hafler DA, Daly MJ, Palotie A, Saarela J, Peltonen L

Getting youth in the game: can we accelerate training for clinician-scientists?

Annals of neurology

Hauser SL, Lowenstein DH, Johnston SC

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility.

Human genetics

Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL, International Multiple Sclerosis Genetics Consortium, Aubin C, Cross AH, Piccio L, Aggarwal NT, Evans D, Hafler DA, Compston A, Hauser SL, Pericak-Vance MA, Haines JL

Ureterocystoplasty: an ideal method for vesical augmentation in children.

Aktuelle Urologie

Fisang C, Hauser S, Müller SC

Status report: the Annals in 2010.

Annals of neurology

Hauser SL, Johnston SC, Ferriero DM, Lowenstein DH, Josephson SA, Messing RO, Oksenberg JR, Stewart AF

Genome-wide patterns of population structure and admixture in West Africans and African Americans.

Proceedings of the National Academy of Sciences of the United States of America

Bryc K, Auton A, Nelson MR, Oksenberg JR, Hauser SL, Williams S, Froment A, Bodo JM, Wambebe C, Tishkoff SA, Bustamante CD

Modified spectrometry (O2C device) of intraoperative microperfusion predicts organ function after kidney transplantation: a pilot study.

Transplantation proceedings

Fechner G, von Pezold J, Luzar O, Hauser S, Tolba RH, Müller SC

Multiple sclerosis susceptibility alleles in African Americans.

Genes and immunity

Johnson BA, Wang J, Taylor EM, Caillier SJ, Herbert J, Khan OA, Cross AH, De Jager PL, Gourraud PA, Cree BC, Hauser SL, Oksenberg JR

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.

Proceedings of the National Academy of Sciences of the United States of America

International MHC and Autoimmunity Genetics Network, Rioux JD, Goyette P, Vyse TJ, Hammarström L, Fernando MM, Green T, De Jager PL, Foisy S, Wang J, de Bakker PI, Leslie S, McVean G, Padyukov L, Alfredsson L, Annese V, Hafler DA, Pan-Hammarström Q, Matell R, Sawcer SJ, Compston AD, Cree BA, Mirel DB, Daly MJ, Behrens TW, Klareskog L, Gregersen PK, Oksenberg JR, Hauser SL

Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.

Annals of neurology

Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH

Balancing risk and reward: the question of natalizumab.

Annals of neurology

Hauser SL, Johnston SC

Disparities in care: guilty until proven innocent.

Annals of neurology

Johnston SC, Hauser SL

Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.

Genes and immunity

McCauley JL, Zuvich RL, Bradford Y, Kenealy SJ, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Mortlock DP, Pericak-Vance MA, Haines JL

Journeys in complex genetics: music and mental illness.

Annals of neurology

Hauser SL, Johnston SC

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.

Nature genetics

De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR

Crowdsourcing scientific innovation.

Annals of neurology

Johnston SC, Hauser SL

Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures.

Neurology

Mowry EM, Beheshtian A, Waubant E, Goodin DS, Cree BA, Qualley P, Lincoln R, George MF, Gomez R, Hauser SL, Okuda DT, Pelletier D

Message from the editor: on humility.

Annals of neurology

Hauser SL, Stewart AF, Johnston SC

Economic over-stimulation?

Annals of neurology

Johnston SC, Hauser SL

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.

European journal of human genetics : EJHG

Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S, Wellcome Trust Case-Control Consortium (WTCCC), Compston A

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis.

Human molecular genetics

Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM, Kappos L, Polman CH, Matthews PM, Hauser SL, Gibson RA, Oksenberg JR, Barnes MR

Personalized genetic scans: with gifts like these...

Annals of neurology

Hauser SL, Johnston SC

The role of the CD58 locus in multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, Hu X, Ashley CW, Choy E, Rioux JD, Pericak-Vance MA, Ivinson A, Booth DR, Stewart GJ, Palotie A, Peltonen L, Dubois B, Haines JL, Weiner HL, Compston A, Hauser SL, Daly MJ, Reich D, Oksenberg JR, Hafler DA

Comparative effectiveness research in the neurosciences.

Annals of neurology

Johnston SC, Hauser SL

Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA.

Archives of neurology

Cree BA, Reich DE, Khan O, De Jager PL, Nakashima I, Takahashi T, Bar-Or A, Tong C, Hauser SL, Oksenberg JR

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

PLoS genetics

Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S, International Multiple Sclerosis Genetics Consortium, De Jager PL, Wicker LS, Todd JA, Hafler DA

Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome.

Neurology

Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL, Pelletier D

Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures.

Brain : a journal of neurology

Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini SE, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

Human molecular genetics

Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR

Peer review at National Institutes of Health: small steps forward.

Annals of neurology

Johnston SC, Hauser SL

Multiple lessons for multiple sclerosis.

The New England journal of medicine

Hauser SL

Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis.

Journal of immunology (Baltimore, Md. : 1950)

Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W, Hauser SL, Barcellos LF, Oksenberg JR

Scripts for science: a new wrinkle on academic ties with industry.

Annals of neurology

Hauser SL, Johnston SC

Investigator balkanization.

Annals of neurology

Johnston SC, Hauser SL

The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research.

American journal of human genetics

Nelson MR, Bryc K, King KS, Indap A, Boyko AR, Novembre J, Briley LP, Maruyama Y, Waterworth DM, Waeber G, Vollenweider P, Oksenberg JR, Hauser SL, Stirnadel HA, Kooner JS, Chambers JC, Jones B, Mooser V, Bustamante CD, Roses AD, Burns DK, Ehm MG, Lai EH

Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event.

Proceedings of the National Academy of Sciences of the United States of America

Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini SE

An election season prescription for healthcare.

Annals of neurology

Hauser SL, Johnston SC

Neurological disease on the global agenda.

Annals of neurology

Johnston SC, Hauser SL

Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis.

Genes and immunity

Barcellos LF, Ramsay PP, Caillier SJ, Sawcer S, Haines J, Schmidt S, Pericak-Vance M, Compston DA, Gabatto P, Hauser SL, Oksenberg JR

The genetics of multiple sclerosis: SNPs to pathways to pathogenesis.

Nature reviews. Genetics

Oksenberg JR, Baranzini SE, Sawcer S, Hauser SL

That vexing problem of compensation.

Annals of neurology

Hauser SL, Johnston SC

Transformative research.

Annals of neurology

Johnston SC, Hauser SL

Cognitive and neurobiological alterations in electromagnetic hypersensitive patients: results of a case-control study.

Psychological medicine

Landgrebe M, Frick U, Hauser S, Langguth B, Rosner R, Hajak G, Eichhammer P

T2 clinical research: judgment day.

Annals of neurology

Claiborne Johnston S, Hauser SL

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis.

The New England journal of medicine

Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH

Neurogenetics in the Annals: dealing with complexity.

Annals of neurology

Oksenberg JR, Hauser SL

Clinical trials: rising costs limit innovation.

Annals of neurology

Johnston SC, Hauser SL

[Ureterocystoplasty in the treatment of "low-compliance" bladder in children].

Der Urologe. Ausg. A

Hauser S, Fisang C, Fechner F, Ellinger J, Haferkamp A, Müller SC

The autoimmune disease-associated IL12B and IL23R polymorphisms in multiple sclerosis.

Human immunology

Begovich AB, Chang M, Caillier SJ, Lew D, Catanese JJ, Wang J, Hauser SL, Oksenberg JR

The upcoming meeting of the ANA.

Annals of neurology

Hauser SL, Johnston SC

SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach.

BMC genomics

McCauley JL, Kenealy SJ, Margulies EH, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Pericak-Vance MA, Haines JL, Mortlock DP

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis.

Nature genetics

Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL, Multiple Sclerosis Genetics Group

Risk alleles for multiple sclerosis identified by a genomewide study.

The New England journal of medicine

International Multiple Sclerosis Genetics Consortium, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, Hauser SL

Matriculating the next generation of clinician-scientists.

Annals of neurology

Hauser SL, Johnston SC

Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring.

The Lancet. Neurology

Kappos L, Bates D, Hartung HP, Havrdova E, Miller D, Polman CH, Ravnborg M, Hauser SL, Rudick RA, Weiner HL, O'Connor PW, King J, Radue EW, Yousry T, Major EO, Clifford DB

Early editorial manuscript screening versus obligate peer review: a randomized trial.

Annals of neurology

Johnston SC, Lowenstein DH, Ferriero DM, Messing RO, Oksenberg JR, Hauser SL

A second major histocompatibility complex susceptibility locus for multiple sclerosis.

Annals of neurology

Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J, Caillier SJ, Ivinson AJ, Green T, Pobywajlo S, Lander ES, Pericak-Vance MA, Haines JL, Daly MJ, Oksenberg JR, Hauser SL, Compston A, Hafler DA, Rioux JD, Sawcer S

Of ghosts and sirens: the subtlest lures of industry.

Annals of neurology

Hauser SL, Johnston SC

Marketing and drug costs: who is laughing and crying?

Annals of neurology

Johnston SC, Hauser SL

Familial effects on the clinical course of multiple sclerosis.

Neurology

Hensiek AE, Seaman SR, Barcellos LF, Oturai A, Eraksoi M, Cocco E, Vecsei L, Stewart G, Dubois B, Bellman-Strobl J, Leone M, Andersen O, Bencsik K, Booth D, Celius EG, Harbo HF, Hauser SL, Heard R, Hillert J, Myhr KM, Marrosu MG, Oksenberg JR, Rajda C, Sawcer SJ, Sørensen PS, Zipp F, Compston DA

A status report on neuroscience research, without grade inflation.

Annals of neurology

Johnston SC, Hauser SL

Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study.

The Lancet. Neurology

Barcellos LF, Kamdar BB, Ramsay PP, DeLoa C, Lincoln RR, Caillier S, Schmidt S, Haines JL, Pericak-Vance MA, Oksenberg JR, Hauser SL

Neurology and medical devices.

Annals of neurology

Johnston SC, Hauser SL

Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes.

Neurogenetics

Motsinger AA, Brassat D, Caillier SJ, Erlich HA, Walker K, Steiner LL, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD

Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis.

Human molecular genetics

Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR

Interleukin-2/interferon-alpha2a/13-retinoic acid-based chemoimmunotherapy in advanced renal cell carcinoma: results of a prospectively randomised trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN).

British journal of cancer

Atzpodien J, Kirchner H, Rebmann U, Soder M, Gertenbach U, Siebels M, Roigas J, Raschke R, Salm S, Schwindl B, Müller SC, Hauser S, Leiber C, Huland E, Heinzer H, Siemer S, Metzner B, Heynemann H, Fornara P, Reitz M

Men transmit MS more often to their children vs women: the Carter effect.

Neurology

Kantarci OH, Barcellos LF, Atkinson EJ, Ramsay PP, Lincoln R, Achenbach SJ, De Andrade M, Hauser SL, Weinshenker BG

Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis.

Genes and immunity

Schmidt S, Pericak-Vance MA, Sawcer S, Barcellos LF, Hart J, Sims J, Prokop AM, van der Walt J, DeLoa C, Lincoln RR, Oksenberg JR, Compston A, Hauser SL, Haines JL, Gregory SG, Multiple Sclerosis Genetics Group

Sleepiness in the elderly.

Annals of neurology

Hauser SL

[Primitive neuroectodermal tumor of the kidney].

Der Urologe. Ausg. A

Ellinger J, Bastian P, Hauser S, Biermann K, Müller S

APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers.

Neurology

Burwick RM, Ramsay PP, Haines JL, Hauser SL, Oksenberg JR, Pericak-Vance MA, Schmidt S, Compston A, Sawcer S, Cittadella R, Savettieri G, Quattrone A, Polman CH, Uitdehaag BM, Zwemmer JN, Hawkins CP, Ollier WE, Weatherby S, Enzinger C, Fazekas F, Schmidt H, Schmidt R, Hillert J, Masterman T, Hogh P, Niino M, Kikuchi S, Maciel P, Santos M, Rio ME, Kwiecinski H, Zakrzewska-Pniewska B, Evangelou N, Palace J, Barcellos LF

Natalizumab: immune effects and implications for therapy.

Annals of neurology

Hauser SL, Weiner HL

Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans.

Genes and immunity

Brassat D, Motsinger AA, Caillier SJ, Erlich HA, Walker K, Steiner LL, Cree BA, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD

Multiple sclerosis: tip of the iceberg?

Annals of neurology

Hauser SL

Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44.

Genes and immunity

Kenealy SJ, Herrel LA, Bradford Y, Schnetz-Boutaud N, Oksenberg JR, Hauser SL, Barcellos LF, Schmidt S, Gregory SG, Pericak-Vance MA, Haines JL

Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.

Human molecular genetics

Traherne JA, Barcellos LF, Sawcer SJ, Compston A, Ramsay PP, Hauser SL, Oksenberg JR, Trowsdale J

Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis.

Journal of neuroimmunology

Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE

Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectations.

Archives of neurology

Frohman EM, Stüve O, Havrdova E, Corboy J, Achiron A, Zivadinov R, Sorensen PS, Phillips JT, Weinshenker B, Hawker K, Hartung HP, Steinman L, Zamvil S, Cree BA, Hauser S, Weiner H, Racke MK, Filippi M

A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility.

Nature genetics

Reich D, Patterson N, De Jager PL, McDonald GJ, Waliszewska A, Tandon A, Lincoln RR, DeLoa C, Fruhan SA, Cabre P, Bera O, Semana G, Kelly MA, Francis DA, Ardlie K, Khan O, Cree BA, Hauser SL, Oksenberg JR, Hafler DA

Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions.

Archives of neurology

Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, Lucchinetti C, Wilken J, Karandikar N, Hemmer B, Monson N, De Keyser J, Hartung H, Steinman L, Oksenberg JR, Cree BA, Hauser S, Racke MK

Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis.

The Journal of allergy and clinical immunology

Menge T, Lalive PH, von Büdingen HC, Cree B, Hauser SL, Genain CP

A high-density screen for linkage in multiple sclerosis.

American journal of human genetics

Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, Schmidt S, Pericak-Vance MA, Akesson E, Hillert J, Datta P, Oturai A, Ryder LP, Harbo HF, Spurkland A, Myhr KM, Laaksonen M, Booth D, Heard R, Stewart G, Lincoln R, Barcellos LF, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL, International Multiple Sclerosis Genetics Consortium

Genetics of multiple sclerosis.

Neurologic clinics

Oksenberg JR, Hauser SL

The HLA locus and multiple sclerosis in Sicily.

Neurology

Brassat D, Salemi G, Barcellos LF, McNeill G, Proia P, Hauser SL, Oksenberg JR, Savettieri G

The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis.

American journal of human genetics

Begovich AB, Caillier SJ, Alexander HC, Penko JM, Hauser SL, Barcellos LF, Oksenberg JR

Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis.

Neurology

Cree BA, Khan O, Bourdette D, Goodin DS, Cohen JA, Marrie RA, Glidden D, Weinstock-Guttman B, Reich D, Patterson N, Haines JL, Pericak-Vance M, DeLoa C, Oksenberg JR, Hauser SL

An update on multiple sclerosis.

Journal of the neurological sciences

Hauser SL

A second-generation genomic screen for multiple sclerosis.

American journal of human genetics

Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, Schmidt S, Pericak-Vance MA, Barcellos LF, Lincoln RR, Oksenberg JR, Hauser SL, Clanet M, Brassat D, Edan G, Yaouanq J, Semana G, Cournu-Rebeix I, Lyon-Caen O, Fontaine B, American-French Multiple Sclerosis Genetics Group

The shape of things to come.

Neurology

Hauser SL

Re: GAMES issue.

Journal of neuroimmunology

Oksenberg JR, Hauser SL

Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping.

Human molecular genetics

Sawcer SJ, Maranian M, Singlehurst S, Yeo T, Compston A, Daly MJ, De Jager PL, Gabriel S, Hafler DA, Ivinson AJ, Lander ES, Rioux JD, Walsh E, Gregory SG, Schmidt S, Pericak-Vance MA, Barcellos L, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL

Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis.

Annals of neurology

Barcellos LF, Begovich AB, Reynolds RL, Caillier SJ, Brassat D, Schmidt S, Grams SE, Walker K, Steiner LL, Cree BA, Stillman A, Lincoln RR, Pericak-Vance MA, Haines JL, Erlich HA, Hauser SL, Oksenberg JR

Methods for high-density admixture mapping of disease genes.

American journal of human genetics

Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D, Daly MJ, Reich D

Analysis of IL4R haplotypes in predisposition to multiple sclerosis.

Genes and immunity

Mirel DB, Barcellos LF, Wang J, Hauser SL, Oksenberg JR, Erlich HA

Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans.

American journal of human genetics

Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, Pericak-Vance MA, Haines JL, Hauser SL

Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study.

Neurogenetics

Pericak-Vance MA, Rimmler JB, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL, Cournu-Rebeix I, Azoulay-Cayla A, Lyon-Caen O, Fontaine B, Duhamel E, Coppin H, Brassat D, Roth MP, Clanet M, Alizadeh M, Yaouanq J, Quelvennec E, Semana G, Edan G, Babron MC, Genin E, Clerget-Darpoux F

Osteopontin polymorphisms and disease course in multiple sclerosis.

Genes and immunity

Caillier S, Barcellos LF, Baranzini SE, Swerdlin A, Lincoln RR, Steinman L, Martin E, Haines JL, Pericak-Vance M, Hauser SL, Oksenberg JR

Interferons in relapsing remitting multiple sclerosis.

Lancet (London, England)

Rudick RA, Cookfair DL, Griffin J, Hauser S, Piantadosi S

Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis.

Genes and immunity

Sriram U, Barcellos LF, Villoslada P, Rio J, Baranzini SE, Caillier S, Stillman A, Hauser SL, Montalban X, Oksenberg JR

HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course.

American journal of human genetics

Barcellos LF, Oksenberg JR, Begovich AB, Martin ER, Schmidt S, Vittinghoff E, Goodin DS, Pelletier D, Lincoln RR, Bucher P, Swerdlin A, Pericak-Vance MA, Haines JL, Hauser SL, Multiple Sclerosis Genetics Group

Multiple susceptibility loci for multiple sclerosis.

Human molecular genetics

Haines JL, Bradford Y, Garcia ME, Reed AD, Neumeister E, Pericak-Vance MA, Rimmler JB, Menold MM, Martin ER, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL, Multiple Sclerosis Genetics Group

Approved and future pharmacotherapy for multiple sclerosis.

The neurologist

Stüve O, Cree BC, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS

The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta.

Journal of neuroimmunology

Villoslada P, Barcellos LF, Rio J, Begovich AB, Tintore M, Sastre-Garriga J, Baranzini SE, Casquero P, Hauser SL, Montalban X, Oksenberg JR

Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination.

Proceedings of the National Academy of Sciences of the United States of America

von Büdingen HC, Hauser SL, Fuhrmann A, Nabavi CB, Lee JI, Genain CP

Neuromyelitis optica.

Seminars in neurology

Cree BA, Goodin DS, Hauser SL

The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study.

Journal of immunology (Baltimore, Md. : 1950)

Koehler NK, Genain CP, Giesser B, Hauser SL

Biological properties and molecular characterization of beet chlorosis virus (BChV).

Archives of virology

Hauser S, Stevens M, Beuve M, Lemaire O

New insights into the genetics of multiple sclerosis.

Journal of rehabilitation research and development

Baranzini SE, Oksenberg JR, Hauser SL

Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis.

American journal of human genetics

Schmidt S, Barcellos LF, DeSombre K, Rimmler JB, Lincoln RR, Bucher P, Saunders AM, Lai E, Martin ER, Vance JM, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines JL, Multiple Sclerosis Genetics Group

Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA).

Genes and immunity

Patarroyo JC, Stuve O, Piskurich JF, Hauser SL, Oksenberg JR, Zamvil SS

Genetic basis for clinical expression in multiple sclerosis.

Brain : a journal of neurology

Barcellos LF, Oksenberg JR, Green AJ, Bucher P, Rimmler JB, Schmidt S, Garcia ME, Lincoln RR, Pericak-Vance MA, Haines JL, Hauser SL, Multiple Sclerosis Genetics Group

Frequency, heterogeneity and encephalitogenicity of T cells specific for myelin oligodendrocyte glycoprotein in naive outbred primates.

European journal of immunology

Villoslada P, Abel K, Heald N, Goertsches R, Hauser SL, Genain CP

Linkage and association analysis of chromosome 19q13 in multiple sclerosis.

Neurogenetics

Pericak-Vance MA, Rimmler JB, Martin ER, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Goodkin DE, Hauser SL

PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.

Nature genetics

Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR

Multiple sclerosis and oligodendroglioma.

Multiple sclerosis (Houndmills, Basingstoke, England)

Green AJ, Bollen AW, Berger MS, Oksenberg JR, Hauser SL

Immune responses against the myelin/oligodendrocyte glycoprotein in experimental autoimmune demyelination.

Journal of clinical immunology

von Büdingen HC, Tanuma N, Villoslada P, Ouallet JC, Hauser SL, Genain CP

Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility.

Journal of neuroimmunology

Green AJ, Barcellos LF, Rimmler JB, Garcia ME, Caillier S, Lincoln RR, Bucher P, Pericak-Vance MA, Haines JL, Hauser SL, Oksenberg JR, Multiple Sclerosis Genetics Group

Multiple sclerosis: genomic rewards.

Journal of neuroimmunology

Oksenberg JR, Baranzini SE, Barcellos LF, Hauser SL

Characterization of the response to myelin basic protein in a non human primate model for multiple sclerosis.

European journal of immunology

Uccelli A, Giunti D, Mancardi G, Caroli F, Fiorone M, Seri M, Hauser SL, Genain CP

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation.

The Journal of biological chemistry

Hauser S, Adelmant G, Sarraf P, Wright HM, Mueller E, Spiegelman BM

Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system.

The Journal of experimental medicine

Villoslada P, Hauser SL, Bartke I, Unger J, Heald N, Rosenberg D, Cheung SW, Mobley WC, Fisher S, Genain CP

Interaction between HLA-DR2 and abnormal brain MRI in optic neuritis and early MS. Optic Neuritis Study Group.

Neurology

Hauser SL, Oksenberg JR, Lincoln R, Garovoy J, Beck RW, Cole SR, Moke PS, Kip KE, Gal RL, Long DT

CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group.

Immunogenetics

Barcellos LF, Schito AM, Rimmler JB, Vittinghoff E, Shih A, Lincoln R, Callier S, Elkins MK, Goodkin DE, Haines JL, Pericak-Vance MA, Hauser SL, Oksenberg JR

A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation.

The Journal of biological chemistry

Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Hiramatsu R, Serhan CN, Spiegelman BM

Chromosome 17q22-q24 and multiple sclerosis genetic susceptibility. American-French Multiple Sclerosis Genetic Group.

Genes and immunity

Fontaine B, Cournu I, Arnaud I, Babron MC, Eichenbaum-Voline S, Oksenberg JR, Pericak-Vance MA, Haines JL, Semama G, Liblau R, Lyon-Caen O, Clerget-Darpoux F, Clanet M, Hauser SL

Autoreactivity to myelin antigens: myelin/oligodendrocyte glycoprotein is a prevalent autoantigen.

Journal of neuroimmunology

Diaz-Villoslada P, Shih A, Shao L, Genain CP, Hauser SL

Linkage analysis of candidate myelin genes in familial multiple sclerosis.

Neurogenetics

Seboun E, Oksenberg JR, Rombos A, Usuku K, Goodkin DE, Lincoln RR, Wong M, Pham-Dinh D, Boesplug-Tanguy O, Carsique R, Fitoussi R, Gartioux C, Reyes C, Ribierre F, Faure S, Fizames C, Gyapay G, Weissenbach J, Dautigny A, Rimmler JB, Garcia ME, Pericak-Vance MA, Haines JL, Hauser SL

An adipogenic cofactor bound by the differentiation domain of PPARgamma.

The EMBO journal

Castillo G, Brun RP, Rosenfield JK, Hauser S, Park CW, Troy AE, Wright ME, Spiegelman BM

Identification of autoantibodies associated with myelin damage in multiple sclerosis.

Nature medicine

Genain CP, Cannella B, Hauser SL, Raine CS

Genetic aspects of multiple sclerosis.

Seminars in neurology

Oksenberg JR, Barcellos LF, Hauser SL

Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis.

Brain : a journal of neurology

Leppert D, Ford J, Stabler G, Grygar C, Lienert C, Huber S, Miller KM, Hauser SL, Kappos L

Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group.

Human molecular genetics

Haines JL, Terwedow HA, Burgess K, Pericak-Vance MA, Rimmler JB, Martin ER, Oksenberg JR, Lincoln R, Zhang DY, Banatao DR, Gatto N, Goodkin DE, Hauser SL

Systemic lupus erythematosus (SLE) and neonatal morbidity and mortality.

Australian and New Zealand journal of medicine

Hauser S

Multiple sclerosis: basic immunology.

The journal of spinal cord medicine

Hauser SL

Characterization of the AD7C-NTP cDNA expression in Alzheimer's disease and measurement of a 41-kD protein in cerebrospinal fluid.

The Journal of clinical investigation

Monte SM, Ghanbari K, Frey WH, Beheshti I, Averback P, Hauser SL, Ghanbari HA, Wands JR

Inhibition of allergic encephalomyelitis in marmosets by vaccination with recombinant vaccinia virus encoding for myelin basic protein.

Journal of neuroimmunology

Genain CP, Gritz L, Joshi N, Panicali D, Davis RL, Whitaker JN, Letvin NL, Hauser SL

Autoimmune (idiopathic) thrombocytopenic purpura.

Lancet (London, England)

Hauser S

Rapid identification of Smith-Lemli-Opitz syndrome homozygotes and heterozygotes (carriers) by measurement of deficient 7-dehydrocholesterol-delta 7-reductase activity in fibroblasts.

Metabolism: clinical and experimental

Shefer S, Salen G, Honda A, Batta A, Hauser S, Tint GS, Honda M, Chen T, Holick MF, Nguyen LB

New insights into the immunogenetics of multiple sclerosis.

Current opinion in neurology

Oksenberg JR, Hauser SL

Creation of a model for multiple sclerosis in Callithrix jacchus marmosets.

Journal of molecular medicine (Berlin, Germany)

Genain CP, Hauser SL

Characterization of the TCRB chain repertoire in the New World monkey Callithrix jacchus.

Journal of immunology (Baltimore, Md. : 1950)

Uccelli A, Oksenberg JR, Jeong MC, Genain CP, Rombos T, Jaeger EE, Giunti D, Lanchbury JS, Hauser SL

Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen.

Journal of immunology (Baltimore, Md. : 1950)

Li Y, Uccelli A, Laxer KD, Jeong MC, Vinters HV, Tourtellotte WW, Hauser SL, Oksenberg JR

Late complications of immune deviation therapy in a nonhuman primate.

Science (New York, N.Y.)

Genain CP, Abel K, Belmar N, Villinger F, Rosenberg DP, Linington C, Raine CS, Hauser SL

Biased expression of T cell receptor genes characterizes activated T cells in multiple sclerosis cerebrospinal fluid.

Journal of neuroscience research

Usuku K, Joshi N, Hatem CJ, Wong MA, Stein MC, Hauser SL

Tumor necrosis factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion.

Human immunology

Garcia-Merino A, Alper CA, Usuku K, Marcus-Bagley D, Lincoln R, Awdeh Z, Yunis EJ, Eisenbarth GS, Brink SJ, Hauser SL

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group.

Nature genetics

Haines JL, Ter-Minassian M, Bazyk A, Gusella JF, Kim DJ, Terwedow H, Pericak-Vance MA, Rimmler JB, Haynes CS, Roses AD, Lee A, Shaner B, Menold M, Seboun E, Fitoussi RP, Gartioux C, Reyes C, Ribierre F, Gyapay G, Weissenbach J, Hauser SL, Goodkin DE, Lincoln R, Usuku K, Oksenberg JR

Genetics of demyelinating diseases.

Brain pathology (Zurich, Switzerland)

Oksenberg JR, Seboun E, Hauser SL

Side effect profile of interferon beta-1b in MS: results of an open label trial.

Neurology

Neilley LK, Goodin DS, Goodkin DE, Hauser SL

Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane.

Journal of immunology (Baltimore, Md. : 1950)

Xia M, Leppert D, Hauser SL, Sreedharan SP, Nelson PJ, Krensky AM, Goetzl EJ

What to tell patients with their first attack of multiple sclerosis.

European neurology

Caplan LR, Achiron A, Hauser SL

Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate.

The Journal of clinical investigation

Genain CP, Nguyen MH, Letvin NL, Pearl R, Davis RL, Adelman M, Lees MB, Linington C, Hauser SL

Stimulation of matrix metalloproteinase-dependent migration of T cells by eicosanoids.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Leppert D, Hauser SL, Kishiyama JL, An S, Zeng L, Goetzl EJ

T cell gelatinases mediate basement membrane transmigration in vitro.

Journal of immunology (Baltimore, Md. : 1950)

Leppert D, Waubant E, Galardy R, Bunnett NW, Hauser SL

Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.

Proceedings of the National Academy of Sciences of the United States of America

Genain CP, Roberts T, Davis RL, Nguyen MH, Uccelli A, Faulds D, Li Y, Hedgpeth J, Hauser SL

Active and passively induced experimental autoimmune encephalomyelitis in common marmosets: a new model for multiple sclerosis.

Annals of neurology

Massacesi L, Genain CP, Lee-Parritz D, Letvin NL, Canfield D, Hauser SL

Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients.

Annals of neurology

Rozniecki JJ, Hauser SL, Stein M, Lincoln R, Theoharides TC

Expression and selective inhibition of constitutive and inducible forms of cyclooxygenase.

Advances in prostaglandin, thromboxane, and leukotriene research

Seibert K, Masferrer J, Zhang Y, Leahy K, Hauser S, Gierse J, Koboldt C, Anderson G, Bremer M, Gregory S

Mediation of inflammation by cyclooxygenase-2.

Agents and actions. Supplements

Seibert K, Masferrer J, Zhang Y, Gregory S, Olson G, Hauser S, Leahy K, Perkins W, Isakson P

Cytokine regulation of eicosanoid generation.

Annals of the New York Academy of Sciences

Isakson P, Hauser S, Zhang Y, Leahy K, Masferrer J, Seibert K

Reexpression of the major histocompatibility complex (MHC) class-I antigen h-2k(b) by m1 (b16-f10) murine melanoma-cells.

International journal of oncology

Calorini L, Simile M, Hauser S, Gattonicelli S

Future role of neurologists.

The Western journal of medicine

Engstrom JW, Hauser SL

In healthy primates, circulating autoreactive T cells mediate autoimmune disease.

The Journal of clinical investigation

Genain CP, Lee-Parritz D, Nguyen MH, Massacesi L, Joshi N, Ferrante R, Hoffman K, Moseley M, Letvin NL, Hauser SL

Prevention strategies for multiple sclerosis.

Annals of neurology

Hauser SL

Unusual organization of the human T-cell receptor beta-chain gene complex is linked to recombination hotspots.

Proceedings of the National Academy of Sciences of the United States of America

Seboun E, Houghton L, Hatem CJ, Lincoln R, Hauser SL

Intermittent cyclophosphamide pulse therapy in progressive multiple sclerosis: final report of the Northeast Cooperative Multiple Sclerosis Treatment Group.

Neurology

Weiner HL, Mackin GA, Orav EJ, Hafler DA, Dawson DM, LaPierre Y, Herndon R, Lehrich JR, Hauser SL, Turel A

Segregation of immunoglobulin heavy chain constant region genes in multiple sclerosis sibling pairs.

Journal of neuroimmunology

Yu JS, Pandey JP, Massacesi L, Lincoln R, Usuku K, Seboun E, Hauser SL

The human T-cell receptor beta-chain repertoire: longitudinal fluctuations and assessment in MHC matched populations.

Immunogenetics

Usuku K, Joshi N, Hatem CJ, Alper CA, Schoenfeld DA, Hauser SL

An antispasticity effect of threonine in multiple sclerosis.

Archives of neurology

Hauser SL, Doolittle TH, Lopez-Bresnahan M, Shahani B, Schoenfeld D, Shih VE, Growdon J, Lehrich JR

Experimental allergic encephalomyelitis in cynomolgus monkeys. Quantitation of T cell responses in peripheral blood.

The Journal of clinical investigation

Massacesi L, Joshi N, Lee-Parritz D, Rombos A, Letvin NL, Hauser SL

T-cell receptors: germline polymorphism and patterns of usage in demyelinating diseases.

Critical reviews in immunology

Usuku K, Joshi N, Hauser SL

Fos RNA accumulation in multiple sclerosis white matter tissue.

Journal of the neurological sciences

Yu JS, Hayashi T, Seboun E, Sklar RM, Doolittle TH, Hauser SL

Multiple sclerosis sibling pairs: clustered onset and familial predisposition.

Neurology

Doolittle TH, Myers RH, Lehrich JR, Birnbaum G, Sheremata W, Franklin GM, Nelson LM, Hauser SL

Insertion/deletion-related polymorphisms in the human T cell receptor beta gene complex.

The Journal of experimental medicine

Seboun E, Robinson MA, Kindt TJ, Hauser SL

Suppression of antibody responses to the acetylcholine receptor by natural antibodies.

European journal of immunology

Sundblad A, Hauser S, Holmberg D, Cazenave PA, Coutinho A

A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complex.

Cell

Seboun E, Robinson MA, Doolittle TH, Ciulla TA, Kindt TJ, Hauser SL

Extended major histocompatibility complex haplotypes in patients with multiple sclerosis.

Neurology

Hauser SL, Fleischnick E, Weiner HL, Marcus D, Awdeh Z, Yunis EJ, Alper CA

A simple method for DNA purification from peripheral blood.

Analytical biochemistry

Ciulla TA, Sklar RM, Hauser SL

Molecular genotypes of the T-cell receptor beta chain in families with multiple sclerosis.

Annals of the New York Academy of Sciences

Ciulla TA, Robinson MA, Seboun E, Doolittle TH, Hayashi T, Kindt TJ, Hauser SL

Extracts of muscle biopsies from patients with spinal muscular atrophies inhibit neurite outgrowth from spinal neurons.

Neurology

Henderson CE, Hauser SL, Huchet M, Dessi F, Hentati F, Taguchi T, Changeux JP, Fardeau M

Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases.

Neurology

Hauser SL, Cazenave PA, Lyon-Caen O, Taguchi T, Huchet M, Nuret H, Changeux JP, Henderson CE

Cognitive function in recent-onset demyelinating diseases.

Archives of neurology

Lyon-Caen O, Jouvent R, Hauser S, Chaunu MP, Benoit N, Widlöcher D, Lhermitte F

Analysis of human T-lymphotrophic virus sequences in multiple sclerosis tissue.

Nature

Hauser SL, Aubert C, Burks JS, Kerr C, Lyon-Caen O, de The G, Brahic M

Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions.

Annals of neurology

Hauser SL, Bhan AK, Gilles F, Kemp M, Kerr C, Weiner HL

Increased IgG secretion by unstimulated mononuclear cells in active multiple sclerosis and functional assessment of the T8 subset.

Clinical immunology and immunopathology

Hauser SL, Ault KA, Johnson D, Hoban C, Weiner HL

Comparative effects of cholestanol and cholesterol on hepatic sterol and bile acid metabolism in the rat.

The Journal of clinical investigation

Shefer S, Hauser S, Salen G, Zaki FG, Bullock J, Salgado E, Shevitz J

Lyt-1 cells mediate acute murine experimental allergic encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)

Hauser SL, Weiner HL, Bhan AK, Shapiro ME, Che M, Aldrich WR, Letvin NL

Altered blood T-cell subsets in patients with multiple sclerosis.

Journal of neuroimmunology

Weiner HL, Hafler DA, Fallis RJ, Johnson D, Ault KA, Hauser SL

Prevention of experimental allergic encephalomyelitis (EAE) in the SJL/J mouse by whole body ultraviolet irradiation.

Journal of immunology (Baltimore, Md. : 1950)

Hauser SL, Weiner HL, Che M, Shapiro ME, Gilles F, Letvin NL

T cell subsets in patients with multiple sclerosis. An overview.

Annals of the New York Academy of Sciences

Weiner HL, Hafler DA, Fallis RJ, Johnson D, Ault KA, Hauser SL

The use of cyclophosphamide in the treatment of multiple sclerosis.

Annals of the New York Academy of Sciences

Weiner HL, Hauser SL, Hafler DA, Fallis RJ, Lehrich JR, Dawson DM

Immunosuppression and plasmapheresis in chronic progressive multiple sclerosis. Design of a clinical trial.

Archives of neurology

Hauser SL, Dawson DM, Lehrich JR, Beal MF, Kevy SV, Weiner HL

Immunohistochemical staining of human brain with monoclonal antibodies that identify lymphocytes, monocytes, and the Ia antigen.

Journal of neuroimmunology

Hauser SL, Bhan AK, Gilles FH, Hoban CJ, Reinherz EL, Schlossman SF, Weiner HL

Epinephrine-induced changes in the distribution of lymphocyte subsets in peripheral blood of humans.

Journal of immunology (Baltimore, Md. : 1950)

Crary B, Hauser SL, Borysenko M, Kutz I, Hoban C, Ault KA, Weiner HL, Benson H

Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH.

The New England journal of medicine

Hauser SL, Dawson DM, Lehrich JR, Beal MF, Kevy SV, Propper RD, Mills JA, Weiner HL

Immunoregulation in multiple sclerosis.

Progress in brain research

Weiner HL, Hauser SL

T-cell subsets in human autoimmune diseases.

Neurology

Hauser SL, Ropper AH, Perlo VP, Reinherz EL, Schlossman SF, Weiner HL

Neuroimmunology I: Immunoregulation in neurological disease.

Annals of neurology

Weiner HL, Hauser SL

Plasmapheresis, lymphocytapheresis, and immunosuppressive drug therapy in multiple sclerosis.

Progress in clinical and biological research

Hauser SL, Fosburg M, Kevy S, Weiner HL

Natural killer cell activity in multiple sclerosis.

Journal of immunology (Baltimore, Md. : 1950)

Hauser SL, Ault KA, Levin MJ, Garovoy MR, Weiner HL

Autism and mental retardation: neuropathologic studies performed in four retarded persons with autistic behavior.

Archives of neurology

Williams RS, Hauser SL, Purpura DP, DeLong GR, Swisher CN

Loss of suppressor T cells in active multiple sclerosis. Analysis with monoclonal antibodies.

The New England journal of medicine

Reinherz EL, Weiner HL, Hauser SL, Cohen JA, Distaso JA, Schlossman SF

Lymphocyte capping in muscular dystrophy.

Neurology

Hauser SL, Weiner HL, Bresnan MJ, Ault KA

A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat.

The Journal of clinical investigation

Shefer S, Cheng FW, Dayal B, Hauser S, Tint GS, Salen G, Mosbach EH

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