PLoS computational biology

Integrative approach to pain genetics identifies pain sensitivity loci across diseases.

PLoS computational biology

Ruau D, Dudley JT, Chen R, Phillips NG, Swan GE, Lazzeroni LC, Clark JD, Butte AJ, Angst MS

Ten years of pathway analysis: current approaches and outstanding challenges.

PLoS computational biology

Khatri P, Sirota M, Butte AJ

PhylOTU: a high-throughput procedure quantifies microbial community diversity and resolves novel taxa from metagenomic data.

PLoS computational biology

Sharpton TJ, Riesenfeld SJ, Kembel SW, Ladau J, O'Dwyer JP, Green JL, Eisen JA, Pollard KS

Identifying a high fraction of the human genome to be under selective constraint using GERP++.

PLoS computational biology

Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, Batzoglou S

Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions.

PLoS computational biology

Chen R, Sigdel TK, Li L, Kambham N, Dudley JT, Hsieh SC, Klassen RB, Chen A, Caohuu T, Morgan AA, Valantine HA, Khush KK, Sarwal MM, Butte AJ

Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets.

PLoS computational biology

Suthram S, Dudley JT, Chiang AP, Chen R, Hastie TJ, Butte AJ

Functional maps of protein complexes from quantitative genetic interaction data.

PLoS computational biology

Bandyopadhyay S, Kelley R, Krogan NJ, Ideker T

Module-based analysis of robustness tradeoffs in the heat shock response system.

PLoS computational biology

Kurata H, El-Samad H, Iwasaki R, Ohtake H, Doyle JC, Grigorova I, Gross CA, Khammash M

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