Science translational medicine

Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.

Science translational medicine

Palanichamy A, Apeltsin L, Kuo TC, Sirota M, Wang S, Pitts SJ, Sundar PD, Telman D, Zhao LZ, Derstine M, Abounasr A, Hauser SL, von Büdingen HC

Selective targeting of TGF-ß activation to treat fibroinflammatory airway disease.

Science translational medicine

Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL

Disease risk factors identified through shared genetic architecture and electronic medical records.

Science translational medicine

Li L, Ruau DJ, Patel CJ, Weber SC, Chen R, Tatonetti NP, Dudley JT, Butte AJ

Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism.

Science translational medicine

Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM

Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity.

Science translational medicine

Liou AP, Paziuk M, Luevano JM, Machineni S, Turnbaugh PJ, Kaplan LM

Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis.

Science translational medicine

Abreu NA, Nagalingam NA, Song Y, Roediger FC, Pletcher SD, Goldberg AN, Lynch SV

Treating human autoimmunity: current practice and future prospects.

Science translational medicine

Rosenblum MD, Gratz IK, Paw JS, Abbas AK

Unraveling how probiotic yogurt works.

Science translational medicine

Bisanz JE, Reid G

A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury.

Science translational medicine

Heine VM, Griveau A, Chapin C, Ballard PL, Chen JK, Rowitch DH

Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Science translational medicine

Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ

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