1. Programmatic implementation of population-based colorectal cancer screening and follow-up of abnormal screening results. We embrace big data and technology to design, develop, and deliver economic and effective services for patients and health systems.

2. Use of human gut samples to study HIV, Covid-19, barrier function, systemic inflammation, inflammatory bowel disease, and microbiome. Approaches employed: organoid models, isolation of epithelial cells and lymphocytes, single cell, spatial transcriptomic analysis, microbial profiling, and blood-based profiling.

The Spitzer Lab is working to develop our understanding of how the immune system coordinates its responses across the organism with an emphasis on tumor immunology. We combine methods in experimental immunology and cancer biology with computation to understand the modes in which the immune system can respond to tumors and to rationally initiate curative immune responses against cancer.

Dr. Jonathan P. Terdiman is a Professor of Clinical Medicine and Surgery and the Chief of the Gastroenterology Division at UCSF Health. He earned his undergraduate degree from Princeton University in 1985 and his medical degree from the Columbia University College of Physicians and Surgeons in 1989. Dr. Terdiman then completed his residency in internal medicine and fellowships in critical care medicine and gastroenterology at UCSF before joining the faculty in 1996.